CAS 145435-72-9

Gamithromicina

Descrição:

Gamithromicina é um antibiótico macrolídeo utilizado principalmente na medicina veterinária, particularmente para o tratamento de infecções respiratórias em gado. É caracterizado por sua atividade antibacteriana de amplo espectro, que ataca uma variedade de bactérias Gram-positivas e algumas Gram-negativas. Gamithromicina atua inibindo a síntese de proteínas bacterianas ao se ligar à subunidade ribossomal 50S, interrompendo efetivamente o crescimento e a reprodução das bactérias. O composto é conhecido por sua longa meia-vida, permitindo uma dosagem menos frequente em comparação com outros antibióticos. É tipicamente administrado por injeção e é preferido por sua eficácia contra patógenos como as espécies de Mycoplasma e Pasteurella. Além disso, Gamithromicina tem um perfil de segurança favorável quando usado conforme as diretrizes em animais, embora seu uso em animais produtores de alimentos seja regulamentado para prevenir resíduos de antibióticos em produtos de carne. Assim como com todos os antibióticos, o uso responsável é crucial para mitigar o risco de desenvolvimento de bactérias resistentes a antibióticos.

Fórmula: C₄₀H₇₆N₂O₁₂

InChI: InChI=1S/C40H76N2O12/c1-15-17-42-21-22(3)33(44)40(11,48)29(16-2)52-36(46)26(7)32(53-30-20-39(10,49-14)34(45)27(8)51-30)25(6)35(38(9,47)19-23(42)4)54-37-31(43)28(41(12)13)18-24(5)50-37/h22-35,37,43-45,47-48H,15-21H2,1-14H3/t22-,23+,24+,25-,26+,27-,28-,29+,30-,31+,32-,33+,34-,35+,37-,38+,39+,40+/m0/s1

Chave InChI: InChIKey=VWAMTBXLZPEDQO-UZSBJOJWSA-N

SMILES: O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)CN(CCC)[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3

Sinónimos:

• (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one
• (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-Cmethyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one
• 1-Oxa-7-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-
• 1-Oxa-7-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5S*,8R*,10R*,11R*,12S*,13S*,14R*)]-
• Gamithormycin
• Gamithromycin
• Ml 1709460
• Zactran
• (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one
• 1-Oxa-7-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-
• 1-Oxa-7-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5S*,8R*,10R*,11R*,12S*,13S*,14R*)]-

1-Oxa-7-azacyclopentadecan-15-one,13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-,[2R-(2R*,3S*,4R*,5S*,8R*,10R*,11R*,12S*,13S*,14R*)]-

CAS: 145435-72-9

Fórmula: C₄₀H₇₆N₂O₁₂

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 777.0376

Ref: IN-DA00HXF7

Gamithromycin

CAS: 145435-72-9

Fórmula: C₄₀H₇₆N₂O₁₂

Pureza: 95.0 - 103.0 % (dried basis)

Cor e Forma: Light-yellow to off-white powder or solid

Peso molecular: 777.04

Ref: 7W-GC5312

(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-Hydroxy-6-Methyltetrahydro-2H-Pyran-2-Yl)Oxy)-2-Ethyl-3,4,10-Trihydroxy-13-(((2R,4R,5S,6S)-5-Hydroxy-4-Methoxy-4,6-Dimethylt

CAS: 145435-72-9

(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-Hydroxy-6-Methyltetrahydro-2H-Pyran-2-Yl)Oxy)-2-Ethyl-3,4,10-Trihydroxy-13-(((2R,4R,5S,6S)-5-Hydroxy-4-Methoxy-4,6-Dimethylt

Pureza: 95%

Peso molecular: 777.04g/mol

Ref: 54-OR1025800

Gamithromycin

CAS: 145435-72-9

Gamithromycin

Pureza: ≥98%

Peso molecular: 777.04g/mol

Ref: 54-BUP14548

Gamithromycin 100 µg/mL in Methanol

Produto Controlado

CAS: 145435-72-9

Fórmula: C₄₀H₇₆N₂O₁₂

Cor e Forma: Single Solution

Peso molecular: 777.04

Ref: 04-A13998500ME-100

Gamithromycin

Produto Controlado

CAS: 145435-72-9

Fórmula: C₄₀H₇₆N₂O₁₂

Cor e Forma: Neat

Peso molecular: 777.04

Ref: 04-C13998500

Gamithromycin

CAS: 145435-72-9

Fórmula: C₄₀H₇₆N₂O₁₂

Peso molecular: 777.05

Ref: 4Z-G-057003

Gamithromycin

CAS: 145435-72-9

Gamithromycin (ML-1709460) is a macrolide compound with antibacterial activity.

Fórmula: C₄₀H₇₆N₂O₁₂

Pureza: 99.38%

Cor e Forma: Solid

Peso molecular: 777.04

Ref: TM-T3629

Gamithromycin

Produto Controlado

CAS: 145435-72-9

Stability Hygroscopic
Applications A macrolide compound which is known to have antibacterial activity, and is useful in the therapy of bacterial infections in mammals. Antibiotic.
References Broto, P., et al.: Eur. J. Med. Chem., 19, 71 (1984), Farrar, V., et al.: J. Med. Chem., 36, 3517 (1993), Clark, D., et al.: J. Pharm. Sci., 88, 807 (1999),

Fórmula: C₄₀H₇₆N₂O₁₂

Cor e Forma: White To Light Yellow

Peso molecular: 777.04

Ref: TR-G195000

Gamithromycin

CAS: 145435-72-9

Gamithromycin is a macrolide antibiotic with action on bacterial protein synthesis and is used for treating respiratory infections in cattle, pigs, and sheep.

Fórmula: C₄₀H₇₆N₂O₁₂

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 777.04 g/mol

Ref: 3D-AG16733