CAS 146-68-9

Cloreto de 2-(4-iodofenil)-3-(4-nitrofenil)-5-feniltetrazólio hidratado

Descrição:

Cloreto de 2-(4-iodofenil)-3-(4-nitrofenil)-5-feniltetrazólio hidratado, com o número CAS 146-68-9, é um composto químico que pertence à classe de sais de tetrazólio. É caracterizado por sua estrutura complexa, que inclui um anel de tetrazólio e vários substituintes aromáticos, especificamente um grupo 4-iodofenila e um grupo 4-nitrofenila. Este composto é tipicamente encontrado como um hidrato, indicando a presença de moléculas de água em sua forma cristalina. É conhecido por sua aplicação em ensaios bioquímicos, particularmente em estudos de viabilidade celular e proliferação, onde serve como um indicador colorimétrico. A presença dos substituintes nitro e iodo contribui para suas propriedades eletrônicas únicas, influenciando sua reatividade e solubilidade. Além disso, o composto pode exibir características espectrais específicas, tornando-o útil em química analítica. Precauções de segurança devem ser tomadas ao manusear esta substância, pois pode representar riscos à saúde devido à sua natureza química.

Fórmula: C₁₉H₁₃ClIN₅O₂

InChI: InChI=1/C19H14IN5O2.ClH/c20-15-6-8-16(9-7-15)23-21-19(14-4-2-1-3-5-14)22-24(23)17-10-12-18(13-11-17)25(26)27;/h1-13H,(H,21,22);1H

Chave InChI: InChIKey=JORABGDXCIBAFL-UHFFFAOYSA-M

SMILES: N(=O)(=O)C1=CC=C([N+]=2N(N=C(N2)C3=CC=CC=C3)C4=CC=C(I)C=C4)C=C1.[Cl-]

Sinónimos:

• 1-iodo-1-nitro-1H-tetrazol-1-ium chloride
• 2-(4-Iodophenyl)-3-(4-Nitrophenyl)-5-Phenyltetrazolium Chloride
• 2-(4-Iodophenyl)-3-(4-Nitrophrnyl)-5-Phenyl-2H-Tetrazoliu Chloride
• 2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride
• 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2,3-dihydro-1H-tetrazole hydrochloride (1:1)
• 2-(p-Iodophenyl)-3-(p-nitrophenyl)-5-phenyltetrazolium chloride
• 2H-Tetrazolium, 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-, chloride
• 2H-Tetrazolium, 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-, chloride (1:1)
• 2H-Tetrazolium, 2-(p-iodophenyl)-3-(p-nitrophenyl)-5-phenyl-, chloride
• 3-(4-iodophenyl)-2-(4-nitrophenyl)-5-phenyl-2H-tetrazol-3-ium
• 3-(4-iodophenyl)-2-(4-nitrophenyl)-5-phenyl-2H-tetrazol-3-ium chloride
• 3-(P-Iodophenyl)-2-(P-Nitrophenyl)-5-Phenyl Tetrazolium Chloride
• 3-(p-Nitrophenyl)-2-(p-iodophenyl)-5-phenyltetrazolium chloride
• 4-Iodonitrotetrazolium Violet
• INT
• Int Chloride
• Iodonitro tetrazolium
• Iodonitrotetrazolium
• Iodonitrotetrazolium Chloride
• Iodonitrotetrazolium purple
• Iodonitrotetrazolium violet
• NSC 27620
• [2-(p-Iodophenyl)-3-(p-nitrophenyl)-5-phenyl-2H-tetrazolium chloride]
• p-Iodonitrotetrazolium violet
• INT, Iodonitrotetrazolium violet
• INT~2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride hydrate
• 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2h-tetrazoliuchloride
• IntA.R.
• 2(4-IODOPHENYL)-3(4-NITROPHENYL)-5-PHENYL-2H-Tetrazolium Chloride (INT)extrapure AR

2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium Chloride [for Biochemical Research]

CAS: 146-68-9

Fórmula: C₁₉H₁₃ClIN₅O₂

Pureza: >98.0%(HPLC)

Cor e Forma: White to Yellow to Orange powder to crystal

Peso molecular: 505.70

Ref: 3B-I0781

2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium Chloride

CAS: 146-68-9

Fórmula: C₁₉H₁₃ClIN₅O₂

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Yellow to Orange powder to crystal

Peso molecular: 505.70

Ref: 3B-I0067

Iodonitrotetrazolium violet, 95%

CAS: 146-68-9

Used for dehydrogenase determination This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part

Fórmula: C₁₉H₁₃ClIN₅O₂

Pureza: 95%

Cor e Forma: Powder, Cream to yellow

Peso molecular: 505.70

Ref: 02-B22301

Iodonitrotetrazolium chloride

CAS: 146-68-9

Fórmula: C₁₉H₁₃ClIN₅O₂

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 505.6963

Ref: IN-DA003R0U

2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride

CAS: 146-68-9

Fórmula: C₁₉H₁₃ClIN₅O₂

Pureza: ≥ 98.0%

Cor e Forma: Light-yellow to yellow powder

Peso molecular: 505.70

Ref: 7W-GC3113

Iodonitrotetrazolium chloride

CAS: 146-68-9

Iodonitrotetrazolium chloride

Fórmula: C₁₉H₁₃IN₅O₂·Cl

Pureza: By hplc: 99.6% by area (Typical Value in Batch COA)

Cor e Forma: almost white powder

Peso molecular: 505.69629g/mol

Ref: 54-BII7020

INT

CAS: 146-68-9

INT

Pureza: ≥98%

Peso molecular: 505.7g/mol

Ref: 54-BUP18178

INT

CAS: 146-68-9

Iodonitrotetrazolium chloride (INT), serves as the electron acceptor in a range of dehydrogenase colorimetric analyses.

Fórmula: C₁₉H₁₃ClIN₅O₂

Pureza: 98.46% - 99.43%

Cor e Forma: Slightly Yellow Powder

Peso molecular: 505.7

Ref: TM-T19374

Iodonitrotetrazolium Chloride (Technical Grade)

CAS: 146-68-9

Fórmula: C₁₉H₁₃IN₅O₂•(Cl)

Cor e Forma: Neat

Ref: TR-I715613

Iodonitrotetrazolium chloride

CAS: 146-68-9

The monotetrazolium salt  Iodonitrotetrazolium chloride (INT), first described by Atkinson et al. (1950), is an iodinated derivative of TTC (2,3,5-Triphenyltetrazolium chloride) with an absorption λmax of 248 nm. The color produced by reduction of this iodonitro compound is a red to purple or brownish formazan with an absorption maximum at 485 to 492 nm (depending on the solvent). INT is often used to visualize dehydrogenase activity histochemically as well as in Western blot staining and as a staining agent for agar colony formation assays.  NAD or NADP-dependent dehydrogenases activity assays: NAD+- or NADP+-dependent dehydrogenase transfers electrons from a substrate (the electron donor, e.g. succinate) to NAD+ or NADP+, forming NADH and NADPH, respectively. Then, the final transfer of hydrogen to the tetrazolium salt is catalyzed by NADH or NADPH dehydrogenases (e.g. succinate dehydrogenase), leading to the reduction of INT and formation of the water-insoluble INT-formazan. 1 mol of formazan is produced for each mole of succinate utilized in the presence of INT. It is important to mention for applications in histology, that INT-formazan precipitates at the site of this latter dehydrogenase but not at the site of the original NAD+- or NADP+-dependent dehydrogenase activity.

Fórmula: C₁₉H₁₃ClIN₅O₂

Peso molecular: 505.7 g/mol

Ref: 3D-I-7630

2(4-Iodophenyl)-3 (4-Nitrophenyl)-5-Phenyl-2H-Tetrazolium Chloride (INT) extrapure AR, 98%

CAS: 146-68-9

Fórmula: C₁₉H₁₃N₅O₂lCI

Pureza: min. 98%

Cor e Forma: White to Dark Yellow to Dark Orange, Crystalline powder

Peso molecular: 505.70

Ref: SR-40686