CAS 1463-10-1

5-Metiluridina

Descrição:

5-Metiluridina, também conhecido como ribotimidina, é um nucleosídeo que consiste na base de pirimidina uracila com um grupo metila ligado à posição 5 do anel de uracila. Essa modificação melhora a estabilidade e funcionalidade das moléculas de RNA, particularmente no contexto do tRNA, onde desempenha um papel no correto dobramento e função da molécula. A fórmula química de 5-Metiluridina é C10H13N2O5, e é caracterizada por sua capacidade de participar de ligações de hidrogênio devido à presença de grupos hidroxila e amino. Este composto é solúvel em água e apresenta um ponto de fusão relativamente baixo. 5-Metiluridina é de interesse na pesquisa bioquímica e tem aplicações potenciais nos campos da biologia molecular e farmacologia, particularmente no estudo das modificações do RNA e seus efeitos na expressão gênica e síntese de proteínas. Seu número CAS, 1463-10-1, é usado para identificação em bancos de dados químicos e contextos regulatórios.

Fórmula: C₁₀H₁₄N₂O₆

InChI: InChI=1/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6+,7?,9-/m1/s1

Chave InChI: InChIKey=DWRXFEITVBNRMK-JXOAFFINSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(C)=C2

Sinónimos:

• 1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-dihydropyrimidine-2,4-dione
• 1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• 1-[3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosylthymine
• 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 5-Me-U
• 5-Methyl-Uridine
• 5-methyl-1-(beta-L-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 5-methyl-1-[(2xi)-beta-D-threo-pentofuranosyl]pyrimidine-2,4(1H,3H)-dione
• 5-methyl-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione
• Ribosylthymine
• Ribothymidine
• Thymine riboside
• Uridine, 5-methyl-
• β-<span class="text-smallcaps">D</span>-Ribofuranoside, thymine-1
• 5-Methyluridine
• 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-D-ribofuranosyl-
• 5-methyuridine
• BETA-RIBOFURANOSIDE
• ribosylthymine/5-methyluridine
• 1-(BETA-D-RIBOFURANOSYL)THYMINE
• 1-β-D-Ribofuranosylthymine
• 5-methyluridine/ribothymidine
• 5-METHYL-D-URIDINE
• 5-Methyluridine (Patent )
• 5-METHYL-1-BETA-D-RIBOFURANOSYL URACIL
• 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• Methyluridine
• 5-methyl-uridin
• THYMINERIBOSIDE
• BETA-D-THYMINE RIBOSIDE
• 1-(BETA-D-RIBOFURANOSYL)THYMIDINE

5-Methyluridine

CAS: 1463-10-1

Fórmula: C₁₀H₁₄N₂O₆

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 258.23

Ref: 3B-M1405

5-Methyluridine, 99%

CAS: 1463-10-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₀H₁₄N₂O₆

Pureza: 99%

Peso molecular: 258.23

Ref: 02-H64259

Uridine, 5-methyl-

CAS: 1463-10-1

Fórmula: C₁₀H₁₄N₂O₆

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 258.2280

Ref: IN-DA001DVT

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine

Pureza: ≥98%

Peso molecular: 258.23g/mol

Ref: 54-BUP18363

5-Methyluridine

CAS: 1463-10-1

Fórmula: C₁₀H₁₄N₂O₆

Peso molecular: 258.23

Ref: 7W-GE5148

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine

Fórmula: C₁₀H₁₄N₂O₆

Pureza: 97%

Cor e Forma: white solid

Peso molecular: 258.23g/mol

Ref: 54-OR52639

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine, a methylated nucleoside in human fluids, is higher in tumor patients; targeted by hypomethylating drugs in cancer therapy.

Fórmula: C₁₀H₁₄N₂O₆

Pureza: 99.72%

Cor e Forma: Solid

Peso molecular: 258.23

Ref: TM-T5282

5-Methyluridine

CAS: 1463-10-1

Applications A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.
References Borek, E., et al.: Cancer Res., 37, 3362 (1977), Sander, G., et al.: Clin. Sci.,71, 367 (1986), Sander, G., et al.: Ann. Nutr. Metab., 30, 137 (1986), Rasmuson, T., et al.: Acta Oncol., 34, 61 (1995),

Fórmula: C₁₀H₁₄N₂O₆

Cor e Forma: Neat

Peso molecular: 258.23

Ref: TR-M338190

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine is a nucleoside that is used to inhibit the replication of cells. It is also used for the treatment of cancer, infectious diseases, and other conditions. 5-Methyluridine inhibits cellular replication by binding to ribothymidine and uridine in the nucleus. The inhibition of cellular proliferation is due to a lack of dna synthesis and RNA synthesis. This nucleoside has been shown to have inhibitory properties against mouse tumor cells grown in vitro, as well as the wild-type strain grown in vivo. 5-Methyluridine may be useful for the treatment of cancer tissues because it can suppress the growth of tumors by inhibiting their ability to replicate.

Fórmula: C₁₀H₁₄N₂O₆

Pureza: Min. 98 Area-%

Cor e Forma: White Powder

Peso molecular: 258.23 g/mol

Ref: 3D-NM04922

5-Methyluridine

CAS: 1463-10-1

Fórmula: C₁₀H₁₄N₂O₆

Pureza: 95%

Cor e Forma: Solid, White to almost white crystal powder

Peso molecular: 258.23

Ref: 10-F212233

5-Methyluridine extrapure, 98%

CAS: 1463-10-1

Fórmula: C₁₀H₁₄N₂O₆

Pureza: min. 98%

Cor e Forma: White to off - white, Crystalline powder, Clear, Colourless

Peso molecular: 258.23

Ref: SR-77337

5-Methyluridine

CAS: 1463-10-1

Fórmula: C₁₀H₁₄N₂O₆

Peso molecular: 258.23

Ref: ST-EA-CP-Z6011