CAS 147-94-4
:Citarabina
Descrição:
Citarabina, também conhecido como arabinosídeo de citosina, é um análogo de nucleosídeo usado principalmente como agente antineoplásico no tratamento de certos tipos de leucemia e linfoma. Sua fórmula química é C9H13N3O5, e apresenta um grupo de açúcar (arabinosídeo) ligado a uma base de citosina. Citarabina é caracterizado por sua capacidade de inibir a síntese de DNA, tornando-o eficaz no alvo de células cancerosas que se dividem rapidamente. Geralmente é administrado por injeção, pois é mal absorvido quando tomado por via oral. O composto é conhecido por sua meia-vida relativamente curta, necessitando de infusão contínua ou dosagem frequente em ambientes clínicos. Os efeitos colaterais comuns incluem mielossupressão, que pode levar a uma maior suscetibilidade a infecções e sangramentos, bem como distúrbios gastrointestinais. Devido ao seu mecanismo de ação, Citarabina é frequentemente usado em combinação com outros agentes quimioterápicos para aumentar a eficácia terapêutica. Seu uso é cuidadosamente monitorado, dado o potencial de toxicidade significativa, particularmente em pacientes com condições preexistentes ou aqueles que recebem terapias concomitantes.
Fórmula:C9H13N3O5
InChI:InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
Chave InChI:InChIKey=UHDGCWIWMRVCDJ-CCXZUQQUSA-N
SMILES:O[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(N)C=C2
Sinónimos:- (Arabinofuranosyl)cytosine
- 1-(Arabinofuranosyl)cytosine
- 1-(β-<span class="text-smallcaps">D</span>-Arabinofuranosyl)cytosine
- 1-(β-D-Arabinofuranosyl)cytosine
- 1-b-D-Arabinofuranosylcytosine
- 1-β-<span class="text-smallcaps">D</span>-Arabinosylcytosine
- 1-β-Arabinofuranosylcytosine
- 1-β-D-Arabinosylcytosine
- 2(1H)-Pyrimidinone, 4-amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
- 2(1H)-Pyrimidinone, 4-amino-1-β-D-arabinofuranosyl-
- 4-Amino-1-Beta-D-Arabinofuranosyl-2(1H)-Pyrimidinone
- 4-Amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidine
- 4-Amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-2(1H)-pyrimidinone
- 4-Amino-1-β-D-Arabinofuranosyl-2(1H)-pyrimidinone
- 4-amino-1-(D-arabinofuranosyl)pyrimidin-2(1H)-one
- 4-amino-1-(beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
- 4-amino-1-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
- 4-amino-1-pentofuranosylpyrimidin-2(1H)-one
- Ac 1075
- Alexan
- Ara-C
- Ara-cell
- ArabinoFuranosylcytosine
- Arabinocytidine
- Arabinocytosine
- Arabinoside C
- Arabitin
- Aracytidine
- Aracytin
- Aracytine
- Arafcyt
- Chx 3311
- Citarabina
- Citozar
- Cyclocide
- Cylocide
- Cylocide N
- Cytarabin
- Cytarabine
- Cytarabinoside
- Cytosar
- Cytosar U
- Cytosine Arabinoside
- Cytosine β-<span class="text-smallcaps">D</span>-arabinofuranoside
- Cytosine β-<span class="text-smallcaps">D</span>-arabinoside
- Cytosine β-D-arabinofuranoside
- Cytosine β-D-arabinoside
- Cytosine, 1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
- Cytosine, 1-β-D-arabinofuranosyl-
- Cytosine-1-β-<span class="text-smallcaps">D</span>-arabinofuranoside
- Cytosine-1-β-D-arabinofuranoside
- Cytosine-1-β-arabinofuranoside
- DepoCyt
- DepoCyte
- Erpalfa
- Iretin
- Mk 8242
- N-(2-oxo-2,3-dihydropyrimidin-4-yl)-D-arabinofuranosylamine
- Nsc 287459
- Nsc 63878
- Sch 900242
- Spongocytidine
- Tarabine PFS
- U 19920
- U 19920A
- Udicil
- ara-Cytosine
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Cytarabine
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C9H13N3O5Cor e Forma:White Off-White PowderPeso molecular:243.085524-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
CAS:Fórmula:C9H13N3O5Pureza:95%Cor e Forma:SolidPeso molecular:243.2166Cytarabine
CAS:Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).Fórmula:C9H13N3O5Pureza:99.83% - 99.93%Cor e Forma:Fine Off-White Crystalline PowderPeso molecular:243.22Cytosine-β-D-arabinofuranoside
CAS:Cytosine-β-D-arabinofuranosideFórmula:C9H13N3O5Pureza:98%Cor e Forma: white crystalline powderPeso molecular:243.22g/molCytarabine-13C-15N2
CAS:Fórmula:C813CH13N15N2O5Cor e Forma:White To Off-White SolidPeso molecular:246.20Cytarabine
CAS:Fórmula:C9H13N3O5Pureza:98.0 - 102.0 % (dried basis)Cor e Forma:White crystalline powderPeso molecular:243.22Cytarabine
CAS:Fórmula:C9H13N3O5Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:243.22Cytarabine
CAS:<p>Applications Cytarabine is used as an antineoplastic and antiviral. It is a selective inhibitor of DNA synthesis. Does not inhibit RNA synthesis.Cytarabine, or cytosine arabinoside, is a chemotherapy agent used mainly in the treatment of cancers of white blood cells such as acute myeloid leukemia (AML) and non-Hodgkin lymphoma. It is also known as Ara-C (Arabinofuranosyl Cytidine). It destroys cancer cells by interfering with DNA synthesis.<br>References Donehower, R.C., et al.: Cancer Treat. Rep., 70, 1059 (1986);<br></p>Fórmula:C9H13N3O5Cor e Forma:NeatPeso molecular:243.22Cytarabine-13C3
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled Cytarabine, a compound used as an antineoplastic and antiviral. A selective inhibitor of DNA synthesis. Does not inhibit RNA synthesis.<br>References Donehower, R.C., et al.: Cancer Treat. Rep., 70, 1059 (1986)<br></p>Fórmula:C613C3H13N3O5Cor e Forma:BeigePeso molecular:246.19Cytarabine
CAS:<p>Anti-viral; anti-neoplastic</p>Fórmula:C9H13N3O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:243.22 g/molCytarabine - Bio-X ™
CAS:<p>Cytarabine is also known as cytosine arabinoside (ara-C) and is a chemotherapy drug that works by inhibiting DNA synthesis. It acts as a nucleoside analogue, which is incorporated into the growing DNA chain during replication. Cytarabine combines a cytosine base with an arabinose sugar (1β-arabinofuranosylcytosine) and is an analog for human deoxycytosine. Cytarabine interferes with DNA synthesis as it is rapidly converted to cytosine arabinoside triphosphate, damaging DNA when cells are in the synthesis phase (S phase). Tumor cells which are highly mitotic and growing rapidly are therefore preferably targeted. Cytarabine also inhibits nucleotide reductase enzymes as well as nuclear polymerases, leading to interruption and inhibition of synthesis, strand breaks and cell death.</p>Fórmula:C9H13N3O5Pureza:(%) Min. 98%Cor e Forma:PowderPeso molecular:243.22 g/mol
![4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0034OE.jpg&w=3840&q=75)
