CAS 147098-20-2

Rosuvastatina Cálcio

Descrição:

Rosuvastatina Cálcio é um agente sintético redutor de lipídios que pertence à classe das estatinas, utilizado principalmente para gerenciar a hiperlipidemia e reduzir o risco de doenças cardiovasculares. Funciona inibindo a HMG-CoA redutase, uma enzima crucial para a biossíntese de colesterol no fígado, reduzindo assim os níveis de colesterol de lipoproteínas de baixa densidade (LDL) e triglicerídeos, enquanto aumenta o colesterol de lipoproteínas de alta densidade (HDL). A substância aparece como um pó branco a off-white e é solúvel em água, o que facilita sua absorção no trato gastrointestinal. Rosuvastatina Cálcio tem uma meia-vida relativamente longa, permitindo a dosagem uma vez ao dia. Geralmente é bem tolerado, mas os efeitos colaterais potenciais podem incluir dor muscular, elevações das enzimas hepáticas e distúrbios gastrointestinais. O composto é frequentemente prescrito em conjunto com modificações no estilo de vida, como dieta e exercício, para aumentar sua eficácia no manejo do colesterol. Como com qualquer medicamento, é essencial monitorar os efeitos adversos e as interações com outros medicamentos durante o tratamento.

Fórmula: C₄₄H₅₄CaF₂N₆O₁₂S₂

InChI: InChI=1S/C22H28FN3O6S.Ca/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32;/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30);/b10-9+;/t16-,17-;/m1./s1

Chave InChI: InChIKey=AVDMILNVMOXCHF-DHMAKVBVSA-N

SMILES: C(=C/[C@H](C[C@H](CC(O)=O)O)O)\C=1C(=NC(N(S(C)(=O)=O)C)=NC1C(C)C)C2=CC=C(F)C=C2.[Ca]

Sinónimos:

• (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
• (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[N-methyl(n-methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-Heptenoic calcium
• (6E)-7-{4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
• (E)-6-[4-(4-fluorophenyl)-6-isopropyl-2-(methyl-methylsulfonyl-amino)pyrimidin-5-yl]-2,4-dihydroxy-hex-5-enoate
• 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6E)-
• 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, calcium salt (2:1), [S-[R*,S*-(E)]]-
• AZD 4522 calcium
• AZD4522 calcium
• Calcium(-1) Anion
• Crestomed
• Crestor
• Fortius
• Razel-F 10
• Rostar
• Rosuvastatin calcium salt
• Rosuvastatin hemicalcium
• Rozavel
• S 4522
• Suvikan

Rosuvastatin Calcium

CAS: 147098-20-2, 287714-41-4

Fórmula: C₄₄H₅₄CaF₂N₆O₁₂S₂

Pureza: >95.0%(HPLC)(N)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 1,001.14

Ref: 3B-R0180

ROSUVASTATIN FOR SYSTEM SUITABILITY CRS

CAS: 147098-20-2

ROSUVASTATIN FOR SYSTEM SUITABILITY CRS

Fórmula: C₂₂H₂₈FN₃O₆S

Cor e Forma: White. Whitish. Powder., White. Whitish. Powder.

Peso molecular: 481.5376

Ref: 41-Y0001721

ROSUVASTATIN CALCIUM CRS

CAS: 147098-20-2

ROSUVASTATIN CALCIUM CRS

Ref: 41-Y0001719

Rosuvastatin Calcium

CAS: 147098-20-2

Sulfonamides used as drugs

Fórmula: Ca(C₂₂H₂₇FN₃O₆S)₂

Cor e Forma: White Powder

Peso molecular: 1000.28351

Ref: 45-1606015

Rosuvastatin calcium

CAS: 147098-20-2

Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic

Fórmula: (C₂₂H₂₇FN₃O₆S)Ca

Pureza: 98.21% - 99.68%

Cor e Forma: White To Off-White Crystalline Solid

Peso molecular: 1001.14

Ref: TM-T1510

6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6E)-

CAS: 147098-20-2

Fórmula: C₄₄H₅₄CaF₂N₆O₁₂S₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1001.1374

Ref: IN-DA001EL3

Rosuvastatin calcium

CAS: 147098-20-2

Rosuvastatin calcium

Pureza: ≥98%

Peso molecular: 1001.14g/mol

Ref: 54-BUP13993

Rosuvastatin Calcium

CAS: 147098-20-2

Rosuvastatin Calcium

Pureza: 97%

Peso molecular: 1001.14g/mol

Ref: 54-IN11947

Rosuvastatin calcium salt

CAS: 147098-20-2

Fórmula: C₂₂H₂₇FN₃O₆S·5Ca

Pureza: 98.0 - 102.0 % (anhydrous basis)

Cor e Forma: White, off-white beige-yellow powder

Peso molecular: 500.57

Ref: 7W-GP1717

Rosuvastatin Calcium Salt

CAS: 147098-20-2

Fórmula: C₂₂H₂₇FN₃O₆S·5Ca

Cor e Forma: White To Off-White Solid

Peso molecular: 480.53 0.5*40.08

Ref: 4Z-R-094

Rosuvastatin Calcium

Produto Controlado

CAS: 147098-20-2

Fórmula: C₂₂H₂₇FN₃O₆S·Ca

Cor e Forma: Neat

Peso molecular: 1001.14

Ref: 86-MM0936.00

Rosuvastatin Calcium RS

CAS: 147098-20-2

Cor e Forma: White Solid Powder

Ref: 2K-1188600021

Rosuvastatin Calcium Salt

Produto Controlado

CAS: 147098-20-2

Fórmula: C₂₂H₂₇FN₃O₆S·Ca

Cor e Forma: White To Off-White

Peso molecular: 1001.14

Ref: TR-R700500

Rosuvastatin calcium - Bio-X ™

CAS: 147098-20-2

Rosuvastatin is a drug that belongs to the group of statins. It is used for the treatment of high cholesterol and as an adjunct therapy for patients with coronary heart disease. Rosuvastatin reduces serum cholesterol by inhibiting HMG-CoA reductase, which is the rate-limiting enzyme in the production of cholesterol. Furthermore, this drug has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.

Fórmula: C₂₂H₂₇FN₃O₆SCa

Pureza: (%) Min. 95%

Cor e Forma: Powder

Peso molecular: 500.57 g/mol

Ref: 3D-BR164378

Rosuvastatin calcium

CAS: 147098-20-2

HMG-CoA reductase inhibitor

Fórmula: (C₂₂H₂₇FN₃O₆S)₂Ca

Pureza: Min. 95 Area-%

Cor e Forma: White Powder

Peso molecular: 1,001.14 g/mol

Ref: 3D-FR27760