CAS 147118-36-3

N-[4-(4-Fluorofenil)-5-(hidroximetil)-6-(1-metiletil)-2-pirimidinil]-N-metilmetanossulfonamida

Descrição:

N-[4-(4-Fluorofenil)-5-(hidroximetil)-6-(1-metiletil)-2-pirimidinil]-N-metilmetanossulfonamida, com número CAS 147118-36-3, é um composto químico que pertence à classe das sulfonamidas. Esta substância apresenta um anel de pirimidina substituído por vários grupos funcionais, incluindo um grupo fluorofenila e um grupo hidroximetila, que contribuem para sua atividade biológica. A presença do grupo metanosulfonamida indica aplicações potenciais em química medicinal, particularmente no desenvolvimento de produtos farmacêuticos. A estrutura do composto sugere que ele pode exibir propriedades como inibição de enzimas ou modulação de vias biológicas, tornando-o de interesse na descoberta de medicamentos. Além disso, o átomo de flúor pode aumentar a lipofilicidade e a estabilidade metabólica, que são características desejáveis no design de medicamentos. No geral, as características estruturais únicas e os grupos funcionais deste composto o posicionam como um candidato para investigação adicional em aplicações terapêuticas, particularmente em áreas relacionadas à oncologia ou doenças infecciosas.

Fórmula: C₁₆H₂₀FN₃O₃S

InChI: InChI=1S/C16H20FN3O3S/c1-10(2)14-13(9-21)15(11-5-7-12(17)8-6-11)19-16(18-14)20(3)24(4,22)23/h5-8,10,21H,9H2,1-4H3

Chave InChI: InChIKey=MSDYDUNHTAYBHV-UHFFFAOYSA-N

SMILES: C(O)C=1C(=NC(N(S(C)(=O)=O)C)=NC1C(C)C)C2=CC=C(F)C=C2

Sinónimos:

• (Methanol) 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulfonylamino)Pyrimidine-5-yl-Methanol
• 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Mehyl-N-Mehylsulfonylamino)Pyrimidine-5-yl-Methanol
• 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methanesulfonylamino) Pyrimidin-5-Methanol
• 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulfonylamino)Pyrimidine-5-Me
• 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulfonylamino)Pyrimidine-5-Methanol
• 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidin-5-Yl-Methanol
• 4-(4-Fluorophenyl)-6-isopropyl-2- [(N-methyl-N- methylsulfony)amino]pyrimidine-5-yl-methanol
• 4-(4-Fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methonol
• 4-(4-Fluorophenyl)-6-isopropyl-2-[N(N-methylsuophonyl)amino]pyrimidine-5-yl-methanol
• 5-(Hydroxymethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine
• 6-(E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-methylsulfonyl-methyl pyrimidine-5-yl)vinyl)(4R,6S)-2,2-dimethyl)(1,3)-dioxane
• Methanesulfonamide, N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-
• Methyl 4-(4-Fluorophenyl)6-Isopropyl-2-(N-Methyl-N-Methylsulfonyl)Amino] Pyrimidine-5-Carbixylate
• N-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methylmethanesulfonamide
• N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide
• N-[4-(4-Fluorophenyl)-6-isopropyl-5-(hydroxymethyl)pyrimidin-2-yl]-N-methylmethanesulfonamide
• N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide
• Rosuvastatin calcium intermediate R-1-2
• Z-7
• Z7
• Zd-2
• Methyl 4-(4-Fluorophenyl)6-Isopropyl-2-(N-Methyl-N-Methylsulfonyl)Amino] Pyrimidine-5-Carbixylate(Z-7)
• 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n- methylsulfonyl)amino]pyrimidine-5-yl-methanol
• 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino] pyrimidine-5-yl-methanol

Methanesulfonamide, N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-

CAS: 147118-36-3

Fórmula: C₁₆H₂₀FN₃O₃S

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 353.4117

Ref: IN-DA001EN2

4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-n-Methylsulfonyl)Amino]Pyrimidine-5-yl-Methanol

CAS: 147118-36-3

4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-n-Methylsulfonyl)Amino]Pyrimidine-5-yl-Methanol

Pureza: 98%

Peso molecular: 353.41g/mol

Ref: 54-PC105229

Rosuvastatin Impurity 40

CAS: 147118-36-3

Fórmula: C₁₆H₂₀FN₃O₃S

Cor e Forma: White To Off-White Solid

Peso molecular: 353.41

Ref: 4Z-R-0944

4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine-5-methanol

Produto Controlado

CAS: 147118-36-3

Fórmula: C₁₆H₂₀FN₃O₃S

Cor e Forma: Neat

Peso molecular: 353.41

Ref: 86-MM0936.02

N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide

Produto Controlado

CAS: 147118-36-3

Applications A Rosuvastatin (R700500) intermediate as HMG-CoA reductase inhibitor.
References Beck, et al.: J. Med. Chem., 33, 52 (1999),

Fórmula: C₁₆H₂₀FN₃O₃S

Cor e Forma: Neat

Peso molecular: 353.41

Ref: TR-F595380

4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsufonyl)amino]pyrimidine-5-yl-methanol

CAS: 147118-36-3

Fórmula: C₁₆H₂₀FN₃O₃S

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 353.41

Ref: 10-F093168

N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide-d6

Produto Controlado

CAS: 147118-36-3

Applications N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide-d6 is an isotope labelled Rosuvastatin (R700500) intermediate as HMG-CoA reductase inhibitor.
References Beck, et al.: J. Med. Chem., 33, 52 (1999),

Fórmula: C₁₆H₁₄D₆FN₃O₃S

Cor e Forma: Neat

Peso molecular: 359.45

Ref: TR-F595382

N-(4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropylpyrimidin-2-yl)-Nmethylmethanesulfonamide

CAS: 147118-36-3

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Fórmula: C₁₆H₂₀FN₃O₃S

Pureza: Min. 95%

Peso molecular: 353.41 g/mol

Ref: 3D-FF57578

Rosuvastatin Hydroxymethyl Impurity

CAS: 147118-36-3

Fórmula: C₁₆H₂₀FN₃O₃S

Peso molecular: 353.41

Ref: ST-EA-CP-R1054