CAS 147489-06-3

t-butil (3R,5S)-7-[2-ciclopropil-4-(4-fluorofenil)quinolin-3-il]-3,5-isopropilidenodióxi-6-heptenoato

Descrição:

A substância química conhecida como t-butil (3R,5S)-7-[2-ciclopropil-4-(4-fluorofenil)quinolin-3-il]-3,5-isopropilidenodióxi-6-heptenoato, com o número CAS 147489-06-3, é um composto orgânico complexo caracterizado por suas características estruturais únicas. Contém um núcleo de quinolina, que é um composto aromático bicíclico conhecido por sua atividade biológica, particularmente em química medicinal. A presença de um grupo ciclopropilo e um substituinte fluorofenila sugere interações potenciais com alvos biológicos, tornando-o de interesse na pesquisa farmacêutica. As funcionalidades isopropilidena e heptenoato indicam que o composto pode exibir perfis específicos de reatividade e estabilidade, potencialmente influenciando sua solubilidade e biodisponibilidade. Além disso, a estereoquímica denotada pela configuração (3R,5S) implica que o composto pode exibir propriedades quirais, o que pode afetar significativamente sua farmacodinâmica e farmacocinética. No geral, a estrutura intrincada e os grupos funcionais deste composto sugerem que ele pode ter aplicações potenciais no desenvolvimento de medicamentos, particularmente na orientação de vias biológicas específicas.

Fórmula: C₃₂H₃₆FNO₄

InChI: InChI=1/C32H36FNO4/c1-31(2,3)38-28(35)19-24-18-23(36-32(4,5)37-24)16-17-26-29(20-12-14-22(33)15-13-20)25-8-6-7-9-27(25)34-30(26)21-10-11-21/h6-9,12-17,21,23-24H,10-11,18-19H2,1-5H3/b17-16+/t23-,24-/m1/s1

Sinónimos:

• tert-butyl [(4R,6S)-6-{(E)-2-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]ethenyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate
• (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-2,2-Dimethyl-1,3-dioxane-6-heptenoic acid,1,1-dimethylethyl ester
• (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-2,2-Dimethyl-1,3-dioxane-6-heptenoate
• P-1
• (4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
• t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6- heptenoate
• t-Butyl-(3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate
• t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-hepte
• (3R,5S,E)-tert-butyl7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate
• t-Bytyl(3R,5S)-7-[2-cyclopropyl-4-(4-fluoropenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate
• 1,3-Dioxane-4-acetic acid,6-[(1E)-2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-,1,1-dimethylethyl ester,(4R,6S)-

1,3-Dioxane-4-acetic acid, 6-[(1E)-2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)-

CAS: 147489-06-3

Fórmula: C₃₂H₃₆FNO₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 517.6309

Ref: IN-DA001EX2

Pitavastatin Impurity 21

CAS: 147489-06-3

Fórmula: C₃₂H₃₆FNO₄

Peso molecular: 517.64

Ref: 4Z-P-6445

T-Butyl (3R,5S)-7-[2-Cyclopropyl-4-(4-Fluorophenyl)Quinolin-3-Yl]-3,5-Isopropylidenedioxy-6-Heptenoate

CAS: 147489-06-3

T-Butyl (3R,5S)-7-[2-Cyclopropyl-4-(4-Fluorophenyl)Quinolin-3-Yl]-3,5-Isopropylidenedioxy-6-Heptenoate

Pureza: 98%

Peso molecular: 517.63g/mol

Ref: 54-PC109247

Pitavastatin Acetonide t-Butyl Ester

CAS: 147489-06-3

Fórmula: C₃₂H₃₆FNO₄

Peso molecular: 517.64

Ref: ST-EA-CP-P23016

t-Butyl (3R,5S)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate

Produto Controlado

CAS: 147489-06-3

Applications t-Butyl (3R,5S)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate is an impurity from the synthesis of HMG-CoA reductase inhibitor Pitavastatin [P531040, (Z)-Pitavastatin Calcium Salt].
References Takahashi, K., et al.: Tetrahdron Lett., 34, 8263 (1993); Takahashi, K., et al.: Bull. Chem. Soc. Japan, 68, 2649 (1995); Hiyama, T., et al.: Bull. Chem. Soc. Japan, 68, 364 (1995); Manne, S., et al.: Oriental J. Chem., 23, 559 (2007)

Fórmula: C₃₂H₃₆FNO₄

Cor e Forma: Neat

Peso molecular: 517.631

Ref: TR-B689830

t-Butyl (3R,5S)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate-d5

Produto Controlado

CAS: 147489-06-3

Fórmula: C₃₂D₅H₃₁FNO₄

Cor e Forma: Neat

Peso molecular: 522.662

Ref: TR-B689832

t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate

CAS: 147489-06-3

t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate is a useful organic compound for research related to life sciences. The catalog number is T66069 and the CAS number is 147489-06-3.

Fórmula: C₃₂H₃₆FNO₄

Cor e Forma: Solid

Peso molecular: 517.641

Ref: TM-T66069