CAS 148296-46-2

GDP-​α-D-​mannose disodium

CAS: 148296-46-2

Fórmula: C₁₆H₂₃N₅Na₂O₁₆P₂

Pureza: 98%

Peso molecular: 649.3048

Ref: IN-DA01MVU4

((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)diphosphate Sodium Salt

CAS: 148296-46-2

((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)diphosphate Sodium Salt

Pureza: 98%

Peso molecular: 649.31g/mol

Ref: 54-OR1063622

Guanosine 5′-diphospho-α-D-mannose disodium salt

CAS: 148296-46-2

Ref: 7W-GN9995

GDP-​α-D-​mannose disodium

CAS: 148296-46-2

GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM

Fórmula: C₁₆H₂₅N₅NaO₁₆P₂

Cor e Forma: Solid

Peso molecular: 628.332

Ref: TM-T11382

GDP-D-mannose disodium salt

CAS: 148296-46-2

GDP-D-mannose is a natural mannosyl donor and substrate for mannosyltransferases that catalyses mannosylation, for instance during the synthesis of the trimannoside core of complex, high-mannose or hybrid N-glycans. GDP-D-mannose is widely used in (chemo)enzymatic synthesis of oligosaccharides and its biosynthesis occurs from glucose-6-phosphate over several steps. GDP-D-mannose consists of a D-mannose unit, α-glycosydically linked to the nucleotide guanosine diphosphate (GDP). Examples of this important reaction would be the transfer of mannosyl moieties onto the dolichol-P-P-GlcNAc2 precursor of N-glycans in the endoplasmatic reticulum, with release of GDP, or the mannosylation reactions during GPI-anchor (bio)synthesis. GDP-D-mannose has also been used for the in vitro synthesis of b-mannan oligosaccharides.

Fórmula: C₁₆H₂₃N₅O₁₆P₂Na₂

Pureza: Min. 90 Area-%

Cor e Forma: White Powder

Peso molecular: 649.3 g/mol

Ref: 3D-MG05610

GDP-D-mannose disodium salt

CAS: 148296-46-2

GDP-D-mannose is a natural mannosyl donor and substrate for mannosyltransferases that catalyses mannosylation, for instance during the synthesis of the trimannoside core of complex, high-mannose or hybrid N-glycans. GDP-D-mannose is widely used in (chemo)enzymatic synthesis of oligosaccharides and its biosynthesis occurs from glucose-6-phosphate over several steps. GDP-D-mannose consists of a D-mannose unit, α-glycosydically linked to the nucleotide guanosine diphosphate (GDP). Examples of this important reaction would be the transfer of mannosyl moieties onto the dolichol-P-P-GlcNAc2 precursor of N-glycans in the endoplasmatic reticulum, with release of GDP, or the mannosylation reactions during GPI-anchor (bio)synthesis. GDP-D-mannose has also been used for the in vitro synthesis of b-mannan oligosaccharides.

Fórmula: C₁₆H₂₃N₅O₁₆P₂Na₂

Pureza: Min. 95 Area-%

Peso molecular: 649.3 g/mol

Ref: 3D-G-8650