CAS 14875-96-8

heme

Descrição:

heme é uma molécula orgânica complexa que desempenha um papel crucial em vários processos biológicos, principalmente como um grupo prostético em hemoproteínas como a hemoglobina e a mioglobina. Consiste em um íon de ferro contido dentro de um anel de porfirina, que é uma estrutura cíclica composta por quatro subunidades de pirrol ligadas por pontes de metina. O ferro em heme pode existir em diferentes estados de oxidação, permitindo que participe de reações redox e se ligue ao oxigênio, monóxido de carbono e outras pequenas moléculas. heme é essencial para o transporte e armazenamento de oxigênio em organismos vivos, bem como para a transferência de elétrons na respiração celular. Sua estrutura permite a ligação reversível do oxigênio, tornando-o vital para o metabolismo aeróbico. Além disso, heme está envolvido em várias reações enzimáticas, incluindo aquelas catalisadas por citocromos, que são importantes para o metabolismo de medicamentos e processos de desintoxicação. O número CAS 14875-96-8 identifica especificamente heme, destacando sua importância na bioquímica e na medicina.

Fórmula: C₃₄H₃₀FeN₄O₄·2H

InChI: InChI=1S/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+2/p-2/b25-13-,26-13?,27-14?,28-15?,29-14-,30-15-,31-16-,32-16?;

Chave InChI: InChIKey=KABFMIBPWCXCRK-ADOXYXQCSA-L

SMILES: C(CC([O-])=O)C=1C=2[N-]3[Fe+2]45[N]6=C(C2)C(CCC([O-])=O)=C(C)C6=CC=7[N-]4C(C=C8[N]5=C(C=C3C1C)C(C=C)=C8C)=C(C=C)C7C.[H+]

Sinónimos:

• 1,3,5,8-Tetramethyl-2,4-divinylporphine-6,7-dipropionic acid ferrous complex
• 21H,23H-Porphine, ferrate(2-) deriv.
• 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-, iron complex
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N21,N22,N23,N24]-, dihydrogen, (SP-4-2)-
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N²¹,N²²,N²³,N²⁴]-, dihydrogen, (SP-4-2)-
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN21,κN22,κN23,κN24]-, hydrogen (1:2), (SP-4-2)-
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN²¹,κN²²,κN²³,κN²⁴]-, dihydrogen, (SP-4-2)-
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN²¹,κN²²,κN²³,κN²⁴]-, hydrogen (1:2), (SP-4-2)-
• Ferroheme
• Ferroprotoporphyrin IX
• Hem Fe
• Heme
• Heme b
• Hydrogen [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN²¹,κN²²,κN²³,κN²⁴]ferrate (heme)
• Iron protoporphyrin
• Iron protoporphyrin IX
• Iron(II) protoporphyrin IX
• Nsc 267100
• Protoheme
• Protoheme IX
• Protoporphyrin IX, iron deriv.
• Protoporphyrin, iron complex
• Reduced hematin
• [3,8,13,17-Tetramethyl-7,12-divinyl-21H,23H-porphine-2,8-dipropanoato(4-)-N21,N22,N23,N24]ferrate(2-) de dihydrogene (SP-4-2)
• [Dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-)]iron

Heme

CAS: 14875-96-8

Fórmula: C₃₄H₃₀FeN₄O₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 616.4873

Ref: IN-DA00AOIN

Ferroheme

CAS: 14875-96-8

Ferroheme

Pureza: ≥95%

Peso molecular: 616.49g/mol

Ref: 54-BUP08076

Hematin (Fe(II) Protoporphyrin IX)

CAS: 14875-96-8

Fórmula: C₃₄H₃₂FeN₄O₄

Peso molecular: 616.50

Ref: 4Z-H-042001

Ferroheme

CAS: 14875-96-8

Ferroheme: iron-containing porphyrin in hemoglobin and other hemeproteins; colors tissues.

Fórmula: C₃₄H₃₂FeN₄O₄

Pureza: 97.63%

Cor e Forma: Solid

Peso molecular: 616.49

Ref: TM-T8948

Ferroprotoporphyrin IX

CAS: 14875-96-8

Stability Light Sensitive
Applications Ferroprotoporphyrin IX is a metabolite formed during biosynthesis and is used to evaluate iron nutrition and metabolism. It is also an iron containing cofactor that is involved with a wide range of cellular functions including oxygen transport.
References Labbe, R.F., et. al.: Clin. Chem., 45, 146 (1999); Yuan, X., et al.: Proc. Natl. Acad. Sci. USA 113, E5144 (2016);

Fórmula: C₃₄H₃₂FeN₄O₄₂

Cor e Forma: Neat

Peso molecular: 616.49

Ref: TR-F307610

HEME

CAS: 14875-96-8

Heme is an iron-containing, non-protein molecule that is essential for life. Heme has a variety of biochemical properties and is important in the regulation of vital biological processes such as oxygen transport and metabolism of nitrogenous compounds. Heme can be found in two forms: heme A and heme B. The former consists of the protein globin combined with ferrous ion, while the latter is formed by the combination of protoporphyrin IX with ferrous ion. The synthesis of heme occurs through a series of reactions that involve oxidation and reduction reactions. The protoheme synthesis pathway results in the production of erythrocruorin, which is then converted to hemes A or B depending on its position in the globin protein chain. In addition to being an important cofactor for enzymes such as cytochrome c oxidase (complex IV), heme also functions as a substrate for heme oxygenase, which removes it from circulation to produce biliver

Fórmula: C₃₄H₃₂FeN₄O₄

Pureza: Min. 95%

Peso molecular: 616.5 g/mol

Ref: 3D-PAA87596