CAS 149809-43-8

2,5-Anidro-1,3,4-trideoxi-2-C-(2,4-difluorofenil)-4-[[[(4-metilfenil)sulfonil]oxi]metil]-1-(1H-1,2,4-triazol-1-il)-D-treo-pentitol

Descrição:

2,5-Anidro-1,3,4-trideoxi-2-C-(2,4-difluorofenil)-4-[[[(4-metilfenil)sulfonil]oxi]metil]-1-(1H-1,2,4-triazol-1-il)-D-treo-pentitol, com número CAS 149809-43-8, é um composto orgânico complexo caracterizado por suas características estruturais únicas. Contém uma espinha dorsal de pentitol, que é um derivado do álcool de açúcar, e é modificado com vários grupos funcionais, incluindo um anel de triazol e um grupo sulfonila. A presença do grupo difluorofenila sugere aplicações potenciais em química medicinal, particularmente no desenvolvimento de produtos farmacêuticos. Este composto pode exibir atividades biológicas específicas devido aos seus componentes estruturais, tornando-o de interesse no design e síntese de fármacos. Suas características anidro e deóxido indicam que pode participar de reações químicas específicas, como glicosilação ou outras transformações relevantes na síntese orgânica. No geral, a estrutura intrincada e a funcionalização do composto sugerem que ele pode ter implicações significativas tanto na pesquisa química quanto em aplicações práticas na indústria farmacêutica.

Fórmula: C₂₁H₂₁F₂N₃O₄S

InChI: InChI=1S/C21H21F2N3O4S/c1-15-2-5-18(6-3-15)31(27,28)30-11-16-9-21(29-10-16,12-26-14-24-13-25-26)19-7-4-17(22)8-20(19)23/h2-8,13-14,16H,9-12H2,1H3/t16-,21-/m0/s1

Chave InChI: InChIKey=DFWVLCJRFGIRAK-KKSFZXQISA-N

SMILES: C([C@@]1(C[C@H](COS(=O)(=O)C2=CC=C(C)C=C2)CO1)C3=C(F)C=C(F)C=C3)N4C=NC=N4

Sinónimos:

• ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)-tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate
• ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl p-tosylate
• ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl4-methylbenzenesulfonate
• (5R-cis)-toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-yl methyl ester
• (5R-cis)-toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4�Ctriazol-1-yl)methyltetrahydrofuran-3-yl methyl ester
• 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-<span class="text-smallcaps">D</span>-threo-pentitol
• 2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-4-({[(4-methylphenyl)sulfonyl]oxy}methyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol
• <span class="text-smallcaps">D</span>-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-
• D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-
• 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol
• (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl) methyltetrahydrofuran-3-ylmethyl ester

(3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate

CAS: 149809-43-8

Fórmula: C₂₁H₂₁F₂N₃O₄S

Pureza: >98.0%(HPLC)

Cor e Forma: White to Orange to Green powder to crystal

Peso molecular: 449.47

Ref: 3B-D4537

((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate

CAS: 149809-43-8

Fórmula: C₂₁H₂₁F₂N₃O₄S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 449.4709

Ref: IN-DA001M15

((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate

CAS: 149809-43-8

((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate

Pureza: ≥98%

Peso molecular: 449.47g/mol

Ref: 54-BUP13893

Posaconazole Diastereoisomer Related Compound 8

CAS: 149809-43-8

Fórmula: C₂₁H₂₁F₂N₃O₄S

Peso molecular: 449.47

Ref: 4Z-P-3888

((3S,5R)-5-((1H-1,2,4-Triazol-1-Yl)Methyl)-5-(2,4-Difluorophenyl)Tetrahydrofuran-3-Yl)Methyl 4-Methylbenzenesulfonate

CAS: 149809-43-8

((3S,5R)-5-((1H-1,2,4-Triazol-1-Yl)Methyl)-5-(2,4-Difluorophenyl)Tetrahydrofuran-3-Yl)Methyl 4-Methylbenzenesulfonate

Pureza: 99%

Peso molecular: 449.47g/mol

Ref: 54-PC104915

((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate

CAS: 149809-43-8

(3S,5R)-5-(1H-1,2,4-Triazole-1-yl)methyl-3-furan antifungal intermediate for posaconazole synthesis with cancer-fighting properties.

Fórmula: C₂₁H₂₁F₂N₃O₄S

Pureza: 99.76%

Cor e Forma: Solid

Peso molecular: 449.47

Ref: TM-T64789

(5R-cis)-Toluene-4-sulfonic Acid 5-(2,4-Difluorophenyl)-5-[1,2,4]triazol-1-ylmethyltetrahydrofuran-3-ylmethyl Ester

Produto Controlado

CAS: 149809-43-8

Applications Posaconazole intermediate. Antifungal agent.
References Ator, M., et al.: J. Med. Chem., 35, 100 (1992), Andriole, V., et al.: J. Antimicrob. Chemother., 44, 151 (1999), Beuchet, P., et al.: Bioorg. Med. Chem., 9, 1599 (1999),

Fórmula: C₂₁H₂₁F₂N₃O₄S

Cor e Forma: Neat

Peso molecular: 449.47

Ref: TR-T535900

((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate

CAS: 149809-43-8

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 449.4700012207031

Ref: 10-F789956

Posaconazole Impurity 29

CAS: 149809-43-8

Fórmula: C₂₁H₂₁F₂N₃O₄S

Peso molecular: 449.47

Ref: ST-EA-CP-P24047