CAS 150238-87-2

H-ALA-ARG-LEU-ASP-VAL-ALA-SER-GLU-PHE-ARG-LYS-LYS-TRP-ASN-LYS-TRP-ALA-LEU-SER-ARG-NH2

Descrição:

A substância química com o nome "H-ALA-ARG-LEU-ASP-VAL-ALA-SER-GLU-PHE-ARG-LYS-LYS-TRP-ASN-LYS-TRP-ALA-LEU-SER-ARG-NH2" é um peptídeo composto por uma sequência de aminoácidos, projetado especificamente para várias aplicações bioquímicas. Sua estrutura inclui uma combinação de cadeias laterais hidrofóbicas, polares e carregadas, que contribuem para suas propriedades gerais, como solubilidade e estabilidade em ambientes aquosos. A presença de múltiplos resíduos de lisina sugere potencial para interações fortes com moléculas carregadas negativamente, enquanto os aminoácidos aromáticos como a fenilalanina e o triptofano podem fornecer características de absorção UV. Este peptídeo pode exibir atividade biológica, potencialmente influenciando processos celulares ou servindo como modelo para estudar interações proteicas. O número CAS 150238-87-2 identifica exclusivamente este composto em bancos de dados químicos, facilitando a pesquisa e aplicação em campos como bioquímica, farmacologia e biologia molecular. Sua síntese e caracterização normalmente envolveriam técnicas como cromatografia líquida de alta eficiência (HPLC) e espectrometria de massas para confirmar pureza e integridade estrutural.

Fórmula: C₁₁₂H₁₇₈N₃₆O₂₇

Sinónimos:

• H-Ala-Arg-Leu-Asp-Val-Ala-Ala-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-Nh2
• Arldvaaefrkkwnkwalsr-Nh2
• Arldvasefrkkwnkwalsr-Nh2
• Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-Nh2
• Pamp
• Pamp (1-20) Human
• Pamp Fragment 1-20 Human

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

Proadrenomedullin, the precursor of adrenomedullin, contains a unique 20-residue sequence termed proadrenomedullin NH₂-terminal 20 peptide (PAMP). The i.v. administration of PAMP produces a rapid and strong hypotensive effect in anesthetized rats. It has been suggested, that PAMP functions as an inhibitory modulator of renal noradrenergic neurotransmission and plays an important role in regulating renal functions. Furthermore, it has been suggested that PAMP can act as an inhibitory regulator of adrenal catecholamine release in vivo and has a potent hyperglycemic effect after intra-third cerebroventricular administration in fasted mice.

Fórmula: C₁₁₂H₁₇₈N₃₆O₂₇

Pureza: 97.2%

Cor e Forma: Whitish

Peso molecular: 2460.87

Ref: 01-4034490

Proadrenomedullin (1-20), human

CAS: 150238-87-2

Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.

Fórmula: C₁₁₂H₁₇₈N₃₆O₂₇

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 2460.84

Ref: TM-TP1490

PAMP (Human)

CAS: 150238-87-2

PAMP (human) is a peptide that binds to the G-protein coupled receptor, M3. It activates the ion channel and induces an influx of calcium ions into cells. This can lead to cell proliferation and differentiation, as well as increased blood flow in the brain. PAMP has been shown to inhibit ligand-induced activation of M3 receptors by competing with the natural ligands for binding sites on these receptors. It has also been shown to have high purity (>95%), and is currently under research for its use in various medical applications such as cancer therapy, pain management, and treatment of respiratory diseases.

Fórmula: C₁₁₂H₁₇₈N₃₆O₂₇

Pureza: Min. 95%

Peso molecular: 2,460.8 g/mol

Ref: 3D-PAM-4291-V

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Fórmula: C₁₁₂H₁₇₈N₃₆O₂₇

Peso molecular: 2,460.87 g/mol

Ref: 3D-PP51060

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

H-ARLDVASEFRKKWNKWALSR-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-ARLDVASEFRKKWNKWALSR-NH2 is provided at greater that >95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-ARLDVASEFRKKWNKWALSR-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-ARLDVASEFRKKWNKWALSR-NH2 at the technical inquiry form on this page

Fórmula: C₁₁₂H₁₇₈N₃₆O₂₇

Pureza: Min. 95%

Peso molecular: 2,460.87 g/mol

Ref: 3D-VAB-07852

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

Custom research peptide; min purity 95%.

Fórmula: C₁₁₂H₁₇₈N₃₆O₂₇

Pureza: Min. 95%

Peso molecular: 2,460.87 g/mol

Ref: 3D-PP17083

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

Proadrenomedullin (1-20) is a polypeptide that is found in human plasma. It is a member of the vasoactive intestinal peptide family and has been shown to be involved in the regulation of vascular tone, blood pressure, and blood vessel permeability. Proadrenomedullin (1-20) also inhibits the production of proinflammatory cytokines such as tumor necrosis factor-alpha, interleukin-6, and interleukin-8. This compound has been shown to have antiviral activity against HIV and herpes simplex virus type 1. Proadrenomedullin (1-20) also functions as a growth factor for tumor cells.

Fórmula: C₁₁₂H₁₇₈N₃₆O₂₇

Pureza: Min. 95%

Peso molecular: 2,460.84 g/mol

Ref: 3D-FP109402