CAS 150322-43-3

Prasugrel

Descrição:

Prasugrel é um medicamento antiplaquetário usado principalmente para reduzir o risco de eventos cardiovasculares em pacientes com síndrome coronariano agudo submetidos a intervenção coronária percutânea. É um derivado da tienopiridina que funciona inibindo irreversivelmente o receptor P2Y12 nas plaquetas, prevenindo assim a agregação plaquetária. Prasugrel é caracterizado por sua rápida absorção e conversão em um metabolito ativo, o que aumenta sua eficácia em comparação com outros agentes antiplaquetários. A fórmula química de Prasugrel é C20H20FNO3S, e tem um peso molecular de aproximadamente 343,44 g/mol. A substância é tipicamente administrada na forma de pró-fármaco, exigindo ativação metabólica para exercer seus efeitos terapêuticos. Prasugrel é conhecido por sua farmacocinética e farmacodinâmica relativamente previsíveis, tornando-se uma escolha preferida em certos contextos clínicos. No entanto, está associado a um aumento do risco de sangramento, exigindo cuidadosa seleção e monitoramento dos pacientes. Seu perfil de segurança e eficácia foi estabelecido por meio de vários ensaios clínicos, contribuindo para sua aceitação na prática clínica para o manejo de eventos cardiovasculares trombóticos.

Fórmula: C₂₀H₂₀FNO₃S

InChI: InChI=1S/C20H20FNO3S/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21/h2-5,10,13,19H,6-9,11H2,1H3

Chave InChI: InChIKey=DTGLZDAWLRGWQN-UHFFFAOYSA-N

SMILES: C(C(=O)C1CC1)(N2CC3=C(CC2)SC(OC(C)=O)=C3)C4=C(F)C=CC=C4

Sinónimos:

• 2-Acetoxy-5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno-[3,2-c]pyridine
• 2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone
• 5-[2-Cyclopropyl-1-(2-Fluorophenyl)-2-Oxoethyl]-4,5,6,7-
• Acetic acid 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl ester
• Cs 747
• Effient free base
• Ethanone, 2-(2-(acetyloxy)-6,7-dihydrothieno(3,2-c)pyridin-5(4H)-yl)-1-cyclopropyl-2-(2-fluorophenyl)-
• Ly 640315
• Prasugrel Base
• Prasugrel [INN]
• Tetrahydrothieno[3,2-C]Pyridin-2-Yl Acetate
• Thieno[3,2-c]pyridine, ethanone deriv.
• [5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
• [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxo-ethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• Prasugrel
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-

Prasugrel

CAS: 150322-43-3

Fórmula: C₂₀H₂₀FNO₃S

Pureza: >98.0%(T)(HPLC)

Cor e Forma: Light yellow to Yellow to Orange powder to crystal

Peso molecular: 373.44

Ref: 3B-P2040

2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone

CAS: 150322-43-3

Fórmula: C₂₀H₂₀FNO₃S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 373.4411

Ref: IN-DA001MIM

Prasugrel

CAS: 150322-43-3

Prasugrel (CS-747) is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME;

Fórmula: C₂₀H₂₀FNO₃S

Pureza: 99.62% - 99.82%

Cor e Forma: White Solid

Peso molecular: 373.44

Ref: TM-T0230

Prasugrel

CAS: 150322-43-3

Fórmula: C₂₀H₂₀FNO₃S

Cor e Forma: Off-White Solid

Peso molecular: 373.44

Ref: 4Z-P-391

Prasugrel

CAS: 150322-43-3

Prasugrel

Pureza: 99%

Peso molecular: 373.44g/mol

Ref: 54-PC109116

Prasugrel

CAS: 150322-43-3

Prasugrel

Pureza: ≥98%

Peso molecular: 373.44g/mol

Ref: 54-BUP15051

Prasugrel

CAS: 150322-43-3

Fórmula: C₂₀H₂₀FNO₃S

Peso molecular: 373.44

Ref: 7W-GP4257

(±)-Prasugrel-d3 (acetate-d3)

CAS: 1127253-02-4, 150322-43-3

Pureza: 99 atom % D

Cor e Forma: Off White Solid

Peso molecular: 376.46

Ref: 3U-D7536

Prasugrel

CAS: 150322-43-3

Pureza: 95.0%

Cor e Forma: Solid

Peso molecular: 373.44000244140625

Ref: 10-F390330

Prasugrel - Bio-X ™

CAS: 150322-43-3

Prasugrel is a thienopyridine prodrug that inhibits the enzyme ADP-dependent P2Y purinergic receptor. Prasugrel inhibits platelet aggregation and the formation of blood clots by blocking the conversion of ADP to ATP on the surface of platelets, thus preventing the release of serotonin from platelets. The reaction products formed by prasugrel are similar to those formed by clopidogrel and include hydrogen sulfate ions and a thiol-containing metabolite. It has also been shown to have potent cytotoxic activity against melanoma cells and anti-inflammatory properties. 
Prasugrel is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₂₀H₂₀FNO₃S

Pureza: (%) Min. 95%

Peso molecular: 373.44 g/mol

Ref: 3D-BP164290

Prasugrel

CAS: 150322-43-3

Prasugrel is a thienopyridine prodrug that inhibits the enzyme ADP-dependent P2Y purinergic receptor. Prasugrel inhibits platelet aggregation and the formation of blood clots by blocking the conversion of ADP to ATP on the surface of platelets, thus preventing the release of serotonin from platelets. The reaction products formed by prasugrel are similar to those formed by clopidogrel and include hydrogen sulfate ions and a thiol-containing metabolite. It has also been shown to have potent cytotoxic activity against melanoma cells and anti-inflammatory properties.

Fórmula: C₂₀H₂₀FNO₃S

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 373.44 g/mol

Ref: 3D-FP10815

Prasugrel

CAS: 150322-43-3

Applications Prasugrel is a platelet inhibitor that reduces aggregation of platelets by being a P2Y12(ADP receptor) inhibitor.

Fórmula: C₂₀H₂₀FNO₃S

Cor e Forma: Neat

Peso molecular: 373.44

Ref: TR-P701188