CAS 151-73-5

Fosfato de sódio de betametasona

Descrição:

Fosfato de sódio de betametasona é um corticosteroide sintético com propriedades anti-inflamatórias e imunossupressoras. É um pó cristalino branco a off-white que é solúvel em água, tornando-o adequado para administração parenteral. Este composto é o sal de sódio do fosfato de betametasona, que melhora sua solubilidade e biodisponibilidade. Fosfato de sódio de betametasona é comumente usado no tratamento de várias condições inflamatórias e alérgicas, incluindo distúrbios de pele, problemas respiratórios e certas doenças autoimunes. Seu mecanismo de ação envolve a modulação da expressão gênica, levando à redução da produção de mediadores inflamatórios. A substância é tipicamente administrada por injeção ou como parte de formulações tópicas. Devido aos seus efeitos potentes, é essencial usar este medicamento sob supervisão médica para evitar potenciais efeitos colaterais, como supressão adrenal ou aumento da suscetibilidade a infecções. No geral, Fosfato de sódio de betametasona é um agente terapêutico valioso no manejo de uma variedade de condições que requerem intervenção com corticosteroides.

Fórmula: C₂₂H₃₀FO₈P·2Na

InChI: InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/t12-,15-,16-,17-,19-,20-,21-,22-;;/m0../s1

Chave InChI: InChIKey=ODEOTKLZVXBMJD-LWCNAHDDSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](F)([C@]4(C)C(CC3)=CC(=O)C=C4)[C@@H](O)C1)[H])(C[C@H](C)[C@@]2(C(COP(=O)(O)O)=O)O)[H].[Na]

Sinónimos:

• 1,4-Pregnadien-9-Alpha-Fluoro-16-Beta-Methyl-11-Beta, 17,21-Triol-3,20-Dione 21-Phosphate, Disodium Salt
• 20-Dione,9-Fluoro-11-Beta,17,21-Trihydroxy-16-Beta-Methyl-Pregna-4-Diene-3
• 21-(Dihydrogenphosphate),Disodiumsalt
• 9A-Fluoro-16B-Methylprednisolone-21-(Disodium Phosphate)
• Bentelan
• Beta Methasone Sodium Phosphate
• Betamethasone 21-(Disodium Phosphate)
• Betamethasone 21-Phosphate Disodium
• Betamethasone 21-Phosphate Disodium Salt
• Betamethasone 21-Phosphate Sodium Salt
• Betamethasone Sodium Phosphate
• Betamethasone disodium phosphate
• Betamethasonedisodiumphosphate
• Betmethasone Disodium Phosphate
• Betnesol
• Celestan
• Celestan solubile
• Disodium (11Beta,16Beta)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Phosphate
• Disodium betamethasone 21-phosphate
• Durabetason
• Nsc 90616
• Pregna-1,4-Diene-3,20-Dione,9-Fluoro-11,17-Dihydroxy-16-Methyl-21-(Phosphonooxy)-,DisodiumSalt,(11Beta,16Beta)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11beta,16beta)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11β,16β)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, sodium salt (1:2), (11β,16β)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 21-(dihydrogen phosphate), disodium salt
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 21-(dihydrogen phosphate), disodium salt (7CI, 8CI)
• Steronema

Betamethasone 21-Phosphate Disodium Salt

CAS: 151-73-5, 360-63-4

Fórmula: C₂₂H₂₈FNa₂O₈P

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 516.41

Ref: 3B-B4110

BETAMETHASONE SODIUM PHOSPHATE RS

CAS: 151-73-5

BETAMETHASONE SODIUM PHOSPHATE RS

Fórmula: C₂₂H₂₈FNa₂O₈P

Peso molecular: 516.4046

Ref: 41-ICRS0229

BETAMETHASONE SODIUM PHOSPHATE CRS

CAS: 151-73-5

BETAMETHASONE SODIUM PHOSPHATE CRS

Fórmula: C₂₂H₂₈FNa₂O₈P

Cor e Forma: White. Whitish. Powder.

Peso molecular: 516.4046

Ref: 41-B1045000

Betamethasone sodium phosphate

CAS: 151-73-5

Betamethasone sodium phosphate

Cor e Forma: Off White Solid

Ref: 47-41

Betamethasone Sodium Phosphate

CAS: 151-73-5

Halogenated derivatives of adrenal cortical hormones

Fórmula: C₂₂H₂₈FNa₂O₈P

Cor e Forma: White Off-White Powder Crystalline Solid

Peso molecular: 516.13012

Ref: 45-1068004

Betamethasone 21-disodium phosphate

CAS: 151-73-5

Fórmula: C₂₂H₂₈FNa₂O₈P

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 516.4046

Ref: IN-DA003O6B

Betamethasone 21-phosphate disodium, Ph. Eur. grade

CAS: 151-73-5

Fórmula: C₂₂H₂₈FNa₂O₈P

Peso molecular: 516.40

Ref: 7W-GK0692

Vista-Methasone

CAS: 151-73-5

Vista-Methasone

Pureza: 97%

Peso molecular: 516.41g/mol

Ref: 54-PC109224

Betamethasone disodium phosphate

CAS: 151-73-5

Betamethasone disodium phosphate

Pureza: ≥98%

Peso molecular: 516.41g/mol

Ref: 54-BUP17318

Betamethasone Sodium Phosphate

Produto Controlado

CAS: 151-73-5

Fórmula: C₂₂H₂₈FO₈PNa

Cor e Forma: White To Off-White

Peso molecular: 516.40

Ref: 86-MM0303.00

Betamethasone 21-phosphate disodium

CAS: 151-73-5

Fórmula: C₂₂H₂₈FNa₂O₈P

Pureza: 98.0 - 102.0 % (anhydrous)

Cor e Forma: White to off-white powder

Peso molecular: 516.40

Ref: 7W-GK8107

Betamethasone-4,6,6,20,20-d5 21-PhosphateDisodium Salt

CAS: 151-73-5

Fórmula: C₂₂H₂₃D₅FNa₂O₈P₂

Peso molecular: 475.46 2 22.99

Ref: 4Z-B-065035

Betamethasone 21-Phosphate Disodium Salt

CAS: 151-73-5

Fórmula: C₂₂H₂₈FNa₂O₈P

Peso molecular: 470.43 2 22.99

Ref: 4Z-B-065046

Betamethasone Sodium Phosphate RS

CAS: 151-73-5

Cor e Forma: White To Almost White Solid Crystal To Powder

Ref: 2K-1148000021

Dexamethasone Sodium phosphate EP Impurity B

CAS: 151-73-5

Fórmula: C₂₂H₂₈FO₈PNa

Peso molecular: 470.43 : 2(23.0)

Ref: ST-EA-CP-D105002

Betamethasone disodium phosphate

CAS: 151-73-5

Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) has anti-inflammatory activity and may be used in the study of rheumatoid arthritis.

Fórmula: C₂₂H₂₈FNa₂O₈P

Pureza: 99.37%

Cor e Forma: White Powder

Peso molecular: 516.41

Ref: TM-T20763

Betamethasone 21-Phosphate Disodium Salt

Produto Controlado

CAS: 151-73-5

Impurity Dexamethasone Sodium Phosphate EP Impurity B
Stability Hygroscopic
Applications Betamethasone 21-Phosphate Disodium Salt (Dexamethasone Sodium Phosphate EP Impurity B) is a Betamethasone derivative. It is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.
References Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003), Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007),

Fórmula: C₂₂H₂₈FO₈P·2Na

Cor e Forma: White To Off-White

Peso molecular: 516.40

Ref: TR-B327030

Betamethasone 21-phosphate disodium

CAS: 151-73-5

Betamethasone 21-phosphate disodium is a synthetic glucocorticoid, which is a man-made analog of naturally occurring steroid hormones produced in the adrenal cortex. Its molecular structure allows for enhanced potency and solubility, making it highly effective for use in various clinical settings. As a glucocorticoid, Betamethasone 21-phosphate disodium functions by binding to glucocorticoid receptors, regulating the expression of anti-inflammatory proteins, and inhibiting the production of pro-inflammatory cytokines. This mechanism of action reduces inflammation and suppresses the immune response, making it valuable in the treatment of conditions that involve excessive inflammation. It is commonly used in the management of conditions such as allergic reactions, certain types of arthritis, and skin diseases. Its ability to rapidly modulate inflammatory pathways also makes it useful in emergency settings for conditions like acute asthma exacerbations and severe allergic reactions. As a water-soluble ester, it allows for diverse administration routes, including oral, intravenous, and topical applications, depending on the clinical requirement.

Fórmula: C₂₂H₂₈FNa₂O₈P

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 516.4 g/mol

Ref: 3D-FB18567

Betamethasone disodium phosphate

CAS: 151-73-5

Pureza: 97%

Peso molecular: 516.41

Ref: 10-F986710

Betamethasone Sodium Phosphate Impurity 1

CAS: 151-73-5

Fórmula: C₂₂H₂₈FO₈P(Na)

Peso molecular: 470.43 : 2(23.0)

Ref: ST-EA-CP-B92010