CAS 151213-15-9

Ácido 1-ciclopropil-6,8-difluoro-1,4-diidro-7-[(4aS,7aS)-octahidro-6H-pirrolo[3,4-b]piridin-6-il]-4-oxo-3-quinolinecarboxílico

Descrição:

Ácido 1-ciclopropil-6,8-difluoro-1,4-diidro-7-[(4aS,7aS)-octahidro-6H-pirrolo[3,4-b]piridin-6-il]-4-oxo-3-quinolinecarboxílico, com número CAS 151213-15-9, é um composto orgânico sintético caracterizado por sua complexa estrutura bicíclica, que inclui um núcleo de quinolina e um moiety de pirrolopiridina. Este composto apresenta múltiplos grupos funcionais, incluindo um ácido carboxílico e substituintes de flúor, que podem influenciar sua reatividade química e atividade biológica. A presença do grupo ciclopropilo pode contribuir para suas propriedades estéricas e eletrônicas únicas. Sua complexidade estrutural sugere aplicações potenciais em química medicinal, particularmente no desenvolvimento de fármacos direcionados a vias biológicas específicas. A difluoração pode aumentar a lipofilicidade e a estabilidade metabólica, enquanto a arquitetura molecular geral pode ser projetada para interagir com receptores ou enzimas específicos. Assim como muitos compostos dessa natureza, entender sua solubilidade, estabilidade e interação com sistemas biológicos seria crucial para avaliar seus potenciais usos terapêuticos.

Fórmula: C₂₀H₂₁F₂N₃O₃

InChI: InChI=1/C20H21F2N3O3/c21-14-6-12-17(25(11-3-4-11)8-13(19(12)26)20(27)28)16(22)18(14)24-7-10-2-1-5-23-15(10)9-24/h6,8,10-11,15,23H,1-5,7,9H2,(H,27,28)/t10-,15+/m0/s1

Chave InChI: InChIKey=WEXQOLCYKFJAJZ-ZUZCIYMTSA-N

SMILES: FC1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N3C[C@]4([C@@](C3)(NCCC4)[H])[H])C5CC5

Sinónimos:

• 1-Cyclopropyl-6,8-difluoro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid
• 3-quinolinecarboxylic acid, 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-
• 6H-Pyrrolo[3,4-b]pyridine, 3-quinolinecarboxylic acid deriv.
• 3-Quinolinecarboxylic acid, 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-, (4aS-cis)-
• Moxifloxacin Imp. A RS IP
• Moxifloxacin hydrochloride impurity A
• Moxifloxacin Related CoMpound A
• Moxifloxacin impurity 1/Moxifloxacin EP Impurity A/Moxifloxacin Difluoro Analog/8-Desmethoxy-8-Fluoro Moxifloxacin/1-cyclopropyl-6,8-difluoro-7-((4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• Moxifloxacin Related Matter 1
• Moxifloxacin impurity A
• 1-cyclopropyl-6-fluoro-7-amino-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 1-cyclopropyl-7-amino-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 7-amino-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylic acid
• 3-Quinolinecarboxylic acid, 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-, (4aS-cis)- USP/EP/BP
• Moxifloxacin EP Impurity A : Moxifloxacin Impurity A
• 1-cyclopropyl-6,8-difluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
• Moxifloxacin EP IMpurity A
• Moxifloxacin Related Compound A (25 mg) (1-cyclopropyl-6,8-difluoro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid)
• 8-Desmethoxy-8-fluoro Moxifloxacin
• 1-Cyclopropyl-6,8-difluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo-[3,4-b]pyridin-6(2H)-yl)-4-oxo-1
• Moxifloxacin Hydrochloride IMpurity-A(EP)(USPRC A)
• Moxifloxacin IMp. A (EP,BP)
• 8-Ddesmethoxy-8-fluoroMoxifloxacin
• 1-Cyclopropyl-6,8-difluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• Moxifloxacin EP Impurity A HCl USP/EP/BP
• Moxifloxacin EP Impurity A/ Moxifloxacin Related Compound A (Moxifloxacin Difluoro Analog)
• 1-Cyclopropyl-6,8-difluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo-[3,4-b]pyridin-6(2H)-yl)-4-oxo-1,4-d
• Moxifloxacin Related Compound A (25 mg) (1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid)
• Moxifloxacin related substance A
• USP Moxifloxacin Related Compound A
• Moxifloxacin impurity 2/Moxifloxacin EP Impurity A HCl/Moxifloxacin Difluoro Analog HCl/8-Desmethoxy-8-fluoro Moxifloxacin HCl/1-cyclopropyl-6,8-difluoro-7-((4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Hydrochloride
• Moxifloxacin Related Matter A
• Mosisasin ImpurityA

Moxifloxacin Related Compound A (1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid)

CAS: 151213-15-9

Compounds containing a quinoline or isoquinoline ring-system, whether or not hydrogenated, not further fused, excluding drugs and pesticides

Fórmula: C₂₀H₂₁F₂N₃O₃

Cor e Forma: White Off-White Powder

Peso molecular: 389.1551

Ref: 45-1448617

3-Quinolinecarboxylic acid, 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-

CAS: 151213-15-9

Fórmula: C₂₀H₂₁F₂N₃O₃

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 389.3958

Ref: IN-DA001N5P

Moxifloxacin EP Impurity A HCl (Moxifloxacin USP Related Compound A HCl)

CAS: 151213-15-9

Fórmula: C₂₀H₂₁F₂N₃O₃·HCl

Cor e Forma: Pale Yellow Solid

Peso molecular: 389.40 36.46

Ref: 4Z-M-2714

1-Cyclopropyl-6,8-difluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

CAS: 151213-15-9

1-Cyclopropyl-6,8-difluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Pureza: 95%

Peso molecular: 389.4g/mol

Ref: 54-PC1007442

1-Cyclopropyl-6,8-difluoro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid

CAS: 151213-15-9

Cor e Forma: Neat

Ref: 86-MM0885.04

Moxifloxacin EP Impurity A

CAS: 151213-15-9

Fórmula: C₂₀H₂₁F₂N₃O₃

Peso molecular: 389.40

Ref: ST-EA-CP-M26001

8-Desmethoxy-8-fluoro Moxifloxacin

CAS: 151213-15-9

Impurity Moxifloaxacin EP Impurity A
Stability Hygroscopic
Applications 8-Desmethoxy-8-fluoro Moxifloxacin (Moxifloaxacin EP Impurity A) is an impurity of Moxifloxacin (M745000).
References Martel, A., et al.: Drugs Fut., 22, 109 (1997), Tobin, C., et al.: J. Antimicrob. Chemother., 42, 278 (1998),

Fórmula: C₂₀H₂₁F₂N₃O₃

Cor e Forma: Neat

Peso molecular: 389.4

Ref: TR-D445850

1-Cyclopropyl-6,8-difluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

CAS: 151213-15-9

Fórmula: C₂₀H₂₁F₂N₃O₃

Pureza: 95%

Peso molecular: 389.403

Ref: 10-F230378

8-Desmethoxy-8-fluoro moxifloxacin

CAS: 151213-15-9

8-Desmethoxy-8-fluoro moxifloxacin is a photolytic drug that is used to treat bacterial infections. It has a high degree of antibacterial activity against methicillin-resistant staphylococcus aureus, including methicillin resistant strains of Staphylococcus epidermidis. 8-Desmethoxy-8-fluoro moxifloxacin hydrochloride is produced by the addition of hydrochloric acid to moxifloxacin, which is then purified by ion chromatography. The compound has been shown to have good stability in human plasma and urine. It also shows excellent recoveries in acetonitrile and quantification results in flow rates.

Fórmula: C₂₀H₂₁F₂N₃O₃

Pureza: Min. 95%

Peso molecular: 389.4 g/mol

Ref: 3D-FD21225