CAS 152-11-4: Cloridrato de verapamil

Descrição: Cloridrato de verapamil é um bloqueador de canais de cálcio usado principalmente no tratamento da hipertensão, angina de peito e certos tipos de arritmias. É um pó cristalino branco a off-white que é solúvel em água e álcool, tornando-o adequado para várias formulações farmacêuticas. O composto atua inibindo a entrada de íons de cálcio nas células musculares cardíacas e lisas, levando ao relaxamento do músculo liso vascular e à diminuição da frequência cardíaca. Esse mecanismo ajuda a reduzir a pressão arterial e a diminuir a carga de trabalho do coração. Cloridrato de verapamil tem uma biodisponibilidade relativamente baixa devido ao extenso metabolismo de primeira passagem, e sua farmacocinética pode ser influenciada por fatores como idade, função hepática e medicamentos concomitantes. Efeitos colaterais comuns podem incluir tontura, dor de cabeça e distúrbios gastrointestinais. Assim como com qualquer medicamento, é essencial usar Cloridrato de verapamil sob supervisão médica para gerenciar efetivamente potenciais interações e contraindicações.

Fórmula: C₂₇H₃₈N₂O₄·ClH

InChI: InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H

Chave InChI: InChIKey=DOQPXTMNIUCOSY-UHFFFAOYSA-N

SMILES: Cl.N#CC(C1=CC=C(OC)C(OC)=C1)(CCCN(C)CCC2=CC=C(OC)C(OC)=C2)C(C)C

Sinónimos:

• (+/-)-5-[N-(3,4-dimethoxyphenylethyl)-METHYLAMINO]-2-(3,4-dimethoxyphenyl)-2-ISOPROPYLVALERONITRILE HYDROCHLORIDE
• 2-(3,4-Dimethoxyphenyl)-5-[[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino]-2-(propan-2-yl)pentanenitrile hydrochloride
• 2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-Dimethoxyphenyl)Ethyl](Methyl)Amino}-2-(Propan-2-Yl)Pentanenitrile Hydrochloride (1:1)
• 5-[(3,4-DIMETHOXYPHENETHYL)METHYLAMINO]-2-(3,4-dimethoxyphenyl)-2-ISOPROPYL-VALERONITRILE HYDROCHLORIDE
• Akilen
• Alpha-(3-((2-(3,4-Dimethoxyphenyl)Ethyl)Methylamino)Propyl)-3,4-Dimethoxy-Alpha-(1-Methylethyl)-
• Alpha-(3-((2-(3,4-Dimethoxyphenyl)Ethyl)Methylamino)Propyl)-3,4-Dimethoxy-Alpha-(1-Methylethyl)-Benzeneacetonitrile Hydrochloride
• Anpec
• Apo-Verap
• Apoacor
• Arapamyl
• Azupamil
• Benzeneacetonitrile Hydrochloride
• Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, hydrochloride (1:1)
• Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, monohydrochloride
• Berkatens
• Calan
• Calan SR
• Calaptin
• Calaptin 240SR
• Calaptin 80
• Cardiabeltin
• Cardiagutt
• Cardibeltin
• Caveril
• Civicor
• Civicor Retard
• Coraver
• Cordilox
• Cordilox SR
• Corpamil
• Covera HS
• Dignover
• Dilacoran
• Dilacoran HTA
• Drosteakard
• Finoptin
• Flamon
• Geangin
• Hexasoptin
• Hexasoptin Retard
• Ikacor
• Ikapress
• Iproveratril
• Iproveratril hydrochloride
• Iproveratrilhydrochloride
• Iso-Card SR
• Isoptin
• Isoptin Retard
• Isoptin SR
• Isoptin, hydrochloride
• Isoptine
• Isoptino
• Izoptin hydrochloride
• Izoptinhydrochloride
• Lekoptin Retard
• Lu 20175
• Manidon
• Manidon Retard
• NSC 272366
• NSC 657799
• Novo-Veramil
• Quasar
• Ravamil SR
• Securon
• Univer
• Valeronitrile, 5-[(3,4-dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropyl-, hydrochloride
• Valeronitrile, 5-[(3,4-dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropyl-, monohydrochloride
• Vasolan
• Vasomil
• Vasopten
• Veracaps SR
• Veracim
• Veracor
• Verahexal
• Veraloc
• Veramex
• Veramil
• Verapamil HCl
• Verapin
• Verapress 240SR
• Veraptin
• Verdilac
• Verelan
• Verelan SR
• Verexamil
• Verogalid ER
• Verpal
• Vetrimil
• dl-Verapamil hydrochloride
• (+/-)-Verapamil hydrochloride
• (+/-)-Verapamil Hydrochloride

(+/-)-Verapamil hydrochloride, 99+%

CAS: 152-11-4

±)-Verapamil hydrochloride is a calcium channel modulator, adrenoceptor antagonist, anti-arrhythmic, cardiac depressant, and coronary vasodilator. …

• Fórmula: C₂₇H₃₉ClN₂O₄
• Pureza: 99+%
• Peso molecular: 491.07

Verapamil hydrochloride

CAS: 152-11-4

• Fórmula: C₂₇H₃₈N₂O₄HCl
• Pureza: 99.7%
• Cor e Forma: White To Off-White
• Peso molecular: 490.25984

Verapamil hydrochloride RS

CAS: 152-11-4

• Fórmula: C₂₇H₃₉ClN₂O₄
• Peso molecular: 491.0626

Verapamil hydrochloride CRS

CAS: 152-11-4

Verapamil Hydrochloride

CAS: 152-11-4

Nitrile function compounds, not elsewhere specified or included

• Fórmula: C₂₇H₃₈N₂O₄·HCl
• Cor e Forma: White Off-White Solid Crystalline Powder
• Peso molecular: 490.25984

5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxy phenyl)-2-isopropylvaleronitrile hydrochloride

CAS: 152-11-4

• Fórmula: C₂₇H₃₉ClN₂O₄
• Pureza: 99%
• Cor e Forma: Solid
• Peso molecular: 491.0626

Verapamil hydrochloride

CAS: 152-11-4

Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia …

• Fórmula: C₂₇H₃₉ClN₂O₄
• Pureza: 98.7% - 99.98%
• Cor e Forma: White To Off-White Powder
• Peso molecular: 491.06

Verapamil hydrochloride

CAS: 152-11-4

• Fórmula: C₂₇H₃₈N₂O₄·HCl
• Pureza: ≥ 98.0%
• Cor e Forma: White to almost white powder
• Peso molecular: 491.07

(±)-Verapamil-d3 HCl(N-methyl-d3)

CAS: 152-11-42714485-49-9

• Pureza: 99 atom % D
• Cor e Forma: White To Off-White Solid
• Peso molecular: 494.09

Verapamil Hydrochloride

CAS: 152-11-4

• Fórmula: C₂₇H₃₈N₂O₄·ClH
• Cor e Forma: Neat
• Peso molecular: 491.06

(±)-Verapamil hydrochloride, 99+%

CAS: 152-11-4

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Fórmula: C₂₇H₃₉ClN₂O₄
• Pureza: 99+%
• Cor e Forma: White to off-white, Powder
• Peso molecular: 491.07

Verapamil Hydrochloride

CAS: 152-11-452-53-9

• Fórmula: C₂₇H₃₈N₂O₄·HCl
• Pureza: >98.0%(T)(HPLC)
• Cor e Forma: White to Almost white powder to crystal
• Peso molecular: 491.07

Verapamil hydrochloride

CAS: 152-11-4

• Fórmula: C₂₇H₃₈N₂O₄·ClH
• Cor e Forma: Neat
• Peso molecular: 491.06

Verapamil hydrochloride

CAS: 152-11-4

• Pureza: 98.0%
• Cor e Forma: Solid
• Peso molecular: 490.259835408

Verapamil HCl

CAS: 152-11-4

• Fórmula: C₂₇H₃₈N₂O₄
• Cor e Forma: White To Off-White Solid
• Peso molecular: 454.61

Verapamil hydrochloride

CAS: 152-11-4

• Fórmula: C₂₇H₃₈N₂O₄·ClH
• Pureza: Tech
• Cor e Forma: white solid
• Peso molecular: 491.06g/mol

Verapamil Hydrochloride

CAS: 152-11-4

Applications A calcium channel blocker. Antihypertensive; antianginal; antiarrhythmic (class IV). Not a dangerous good if …

• Fórmula: C₂₇H₃₈N₂O₄·ClH
• Cor e Forma: Neat
• Peso molecular: 491.06

Verapamil-d3 Hydrochloride

CAS: 152-11-4

Applications Verapamil-d3 Hydrochloride is the labeled analogue of Verapamil Hydrochloride (V125000), which is a calcium …

• Fórmula: C₂₇D₃H₃₅N₂O₄·ClH
• Cor e Forma: Neat
• Peso molecular: 457.633646

Verapamil hydrochloride

CAS: 152-11-4

L-type calcium channel blocker

• Fórmula: C₂₇H₃₉ClN₂O₄
• Pureza: Min. 95%
• Cor e Forma: Powder
• Peso molecular: 491.06 g/mol

Verapamil HCl - Bio-X ™

CAS: 152-11-4

Verapamil is drug that belongs to the class of drugs known as calcium channel blockers. …

• Fórmula: C₂₇H₃₈N₂O₄•HCl
• Pureza: Min. 95%
• Cor e Forma: Powder
• Peso molecular: 491.06 g/mol