CAS 153-91-3

A-metil-dl-triptofano

Descrição:

A-metil-dl-triptofano, com o número CAS 153-91-3, é um derivado de aminoácido que está estruturalmente relacionado com o aminoácido essencial triptofano. Apresenta um grupo metila ligado ao carbono alfa, o que altera suas propriedades bioquímicas em comparação com seu composto original. Este composto é frequentemente utilizado em pesquisas bioquímicas, particularmente em estudos envolvendo síntese de proteínas e metabolismo, pois pode atuar como um análogo do triptofano. Sabe-se que A-metil-dl-triptofano inibe a atividade de certas enzimas envolvidas no metabolismo do triptofano, tornando-se uma ferramenta valiosa no estudo das vias metabólicas. Normalmente é um sólido cristalino branco a off-white e é solúvel em solventes polares. A estrutura única do composto permite que ele interaja com vários sistemas biológicos, influenciando processos como a síntese de neurotransmissores e o dobramento de proteínas. Assim como muitos derivados de aminoácidos, é importante manusear A-metil-dl-triptofano com cuidado em ambientes de laboratório, aderindo aos protocolos de segurança para mitigar quaisquer perigos potenciais.

Fórmula: C₁₂H₁₄N₂O₂

Sinónimos:

• Alpha-Methyl-DL-Tryptophan
• H-.alpha.-Me-DL-Trp-OH
• A-Methyl-L-Tryptophan

H-α-Me-DL-Trp-OH

CAS: 153-91-3

Bachem ID: 4008387.

Fórmula: C₁₂H₁₄N₂O₂

Pureza: > 99%

Cor e Forma: White Powder

Peso molecular: 218.26

Ref: 01-4008387

α-methyl-DL-tryptophan

CAS: 153-91-3

Fórmula: C₁₂H₁₄N₂O₂

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 218.2518

Ref: IN-DA00382A

α-Methyl-DL-tryptophan

CAS: 153-91-3

α-Methyl-DL-tryptophan

Pureza: ≥95%

Peso molecular: 218.26g/mol

Ref: 54-OR1005118

DL-α-Methyltryptophan

CAS: 153-91-3

DL-alpha-Methyltryptophan is a metabolite of the amino acid tryptophan. It is a monoamine neurotransmitter that has been implicated in brain function and inflammatory lesions. DL-alpha-Methyltryptophan can be used as a potential drug target for the treatment of Parkinson's disease, depression, and anxiety disorders. The hydroxyl group on the indole ring of DL-alpha-Methyltryptophan gives it an increased reactivity with oxygen, which allows it to be oxidized by monoamine oxidase B (MAO B) to 3-hydroxyanthranilic acid. This reaction can be inhibited by MAO A inhibitors such as clorgyline or selegiline. The oxidation of DL-alpha-Methyltryptophan leads to increased concentrations of serotonin in the brain and increased activity of aminotransferases.

Fórmula: C₁₂H₁₄N₂O₂

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 218.25 g/mol

Ref: 3D-FM48617

2-Amino-3-(1H-indol-3-yl)-2-methylpropanoic acid

CAS: 153-91-3

Fórmula: C₁₂H₁₄N₂O₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 218.256

Ref: 10-F463127

α-Methyl-DL-tryptophan

CAS: 153-91-3

Applications α-methyl-DL-tryptophan is used as a blocker of ATBo, an amino acid transporter whose expression is upregulated in cancer. It is also a substrate or non-transported inhibitor of the amino acid transporter PAT2 (slc36a2).
References Karunakaran, J., et al.: J. Biochem., 414, 343 (2008); Edwards, N., et al.: Biochimica et Biophysica Acta, Biomembranes, 1808, 260 (2011)

Fórmula: C₁₂H₁₄N₂O₂

Cor e Forma: Off White Solid

Peso molecular: 218.25

Ref: TR-M327120

α-Methyl-DL-tryptophan

CAS: 153-91-3

Alpha-methyl-DL-tryptophan is a useful building block that is used as a reaction component in the synthesis of other compounds. It is a versatile building block that can be used to synthesize complex compounds and as a necessary intermediate in the synthesis of other compounds. Alpha-methyl-DL-tryptophan is an important reagent for research purposes, and is also a speciality chemical. This compound has been shown to have beneficial effects on the central nervous system and may have potential therapeutic uses for neurological disorders (e.g., Parkinson's disease). Alpha-methyl-DL-tryptophan has been shown to be safe with minimal side effects when given at appropriate doses, but it should not be used by pregnant women or patients with epilepsy or depression.

Fórmula: C₁₂H₁₄N₂O₂

Pureza: Min. 97.0 Area-%

Peso molecular: 218.26 g/mol

Ref: 3D-M-5098