CAS 15318-45-3

tiamfenicol

Descrição:

tiamfenicol é um antibiótico de amplo espectro pertencente à classe dos antibióticos fenicol, utilizado principalmente por suas propriedades antibacterianas. É eficaz contra uma variedade de bactérias Gram-positivas e Gram-negativas, tornando-se útil no tratamento de infecções causadas por esses microrganismos. tiamfenicol atua inibindo a síntese de proteínas bacterianas, direcionando-se especificamente à subunidade ribossomal 50S, o que interrompe o crescimento e a reprodução das bactérias. Este composto é frequentemente utilizado na medicina veterinária e tem aplicações na medicina humana, particularmente em casos onde outros antibióticos podem ser ineficazes ou contraindicados. tiamfenicol é conhecido por sua capacidade de penetrar nos tecidos e alcançar concentrações terapêuticas, o que é vantajoso no tratamento de infecções sistêmicas. No entanto, seu uso está associado a potenciais efeitos colaterais, incluindo supressão da medula óssea e o risco de anemia aplástica, levando a restrições em algumas regiões. A substância é tipicamente administrada por via oral ou por injeção, e sua farmacocinética pode variar com base na via de administração. No geral, tiamfenicol é um antibiótico valioso com aplicações e considerações específicas na prática clínica.

Fórmula: C₁₂H₁₅Cl₂NO₅S

InChI: InChI=1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1

Chave InChI: InChIKey=OTVAEFIXJLOWRX-NXEZZACHSA-N

SMILES: [C@@H]([C@H](NC(C(Cl)Cl)=O)CO)(O)C1=CC=C(S(C)(=O)=O)C=C1

Sinónimos:

• (2′R,3′R)-Thiamphenicol
• 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
• 2,2-dichloro-N-{1,3-dihydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide
• 8065Cb
• <span class="text-smallcaps">D</span>-Thiocymetin
• <span class="text-smallcaps">D</span>-Thiophenicol
• <span class="text-smallcaps">D</span>-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol
• <span class="text-smallcaps">D</span>-threo-(1R,2R)-1-(p-Methylsulfonylphenyl)-2-dichloroacetamido-1,3-propanediol
• Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-
• Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R*,R*)]-
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]-, <span class="text-smallcaps">D</span>-threo-(+)-
• Dextrosulphenidol
• Methylsulfonyl chloramphenicol
• NSC 522822
• Thiocymetin
• Thiophenicol
• Tirsan
• Win 5063-2
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]-, D-threo-(+)-
• D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-P-(METHYL-SULFONYL)PHENETHYL]ACETAMIDE
• 98.0-100.5% (Assay)
• ThiocyMetin, Thiophenicol, Win 5062-2, NSC 522822
• D-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol
• Acetamide, 2,2-dichloro-N-[b-hydroxy-a-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]-, D-threo-(+)- (8CI)
• Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]- (9CI)
• D-Thiophenicol
• D-THREO-2,2-DICHLORO-N-(BETA-HYDROXY-ALPHA-[HYDROXYMETHYL]-4-[METHYLSULFONYL]PHENETHYL)ACETAMIDE
• 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
• Acetamide, 2,2-dichloro-N-(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-4-(methylsulfonyl)phenylethyl-
• 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-hydroxymethyl-2-(4-methylsulfonylphenyl)ethyl]acetamide
• D-threo-(1R,2R)-1-(p-Methylsulfonylphenyl)-2-dichloroacetamido-1,3-propanediol
• acetamide,2,2-dichloro-n-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl
• D-threo-2,2-Dichloro-N-(b-hydroxy-a-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide
• D-Thiocymetin
• 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-[4-(methylsulfonyl)phenyl]-2-propyl]acetamide
• Thiamphenicol,D-threo-2,2-Dichloro-N-(β-hydroxy-α-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide
• d-threo-2,2-dichloro-n-(β-hydroxy-α-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide
• THIAMPHENICOL
• 8065c.b.
• 2,2-Dichloro-N[(1R,2R)-2-hydroxy-1-hydroxymethyl-2-(4-methylsulphonylphenyl)-acetamide
• ThiaMphenicol API
• ThiaMphenicol / Methylsulfonyl chloraMphenicol
• ThiamphenicolBP,
• Neomyson
• (+)-2,2-Dichloro-N-[(αR,βR)-β-hydroxy-α-(hydroxymethyl)-4-(methylsulfonyl)phenethyl]acetamide
• THIAMPHENICHOL

Thiamphenicol (THP), 98%

CAS: 15318-45-3

Fórmula: C₁₂H₁₅Cl₂NO₅S

Pureza: min. 98%

Cor e Forma: White to off white, Crystalline powder

Peso molecular: 356.22

Ref: SR-79903

Thiamphenicol

CAS: 15318-45-3

Fórmula: C₁₂H₁₅Cl₂NO₅S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 356.21

Ref: 10-F510285

Thiamphenicol

CAS: 15318-45-3

Thiamphenicol is a semisynthetic derivative of chloramphenicol with action on bacterial protein synthesis inhibition and is used for treating bacterial infections, particularly in veterinary medicine.

Fórmula: C₁₂H₁₅Cl₂NO₅S

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 356.22 g/mol

Ref: 3D-AT38721

Thiamphenicol

CAS: 15318-45-3

Fórmula: C₁₂H₁₅Cl₂NO₅S

Peso molecular: 356.21

Ref: ST-EA-CP-T147000