CAS 154445-77-9

N5-[[[(2,3-Diidro-2,2,4,6,7-pentametil-5-benzofurano)sulfonil]amino]iminometil]-N2-[(9H-fluoren-9-ilmetoxi)carbonil]-L-ornitina

Descrição:

A substância química conhecida como N5-[[[(2,3-Diidro-2,2,4,6,7-pentametil-5-benzofurano)sulfonil]amino]iminometil]-N2-[(9H-fluoren-9-ilmetoxi)carbonil]-L-ornitina, com o número CAS 154445-77-9, é um composto orgânico complexo caracterizado por sua intrincada estrutura molecular. Apresenta um grupo sulfonamida, conhecido por sua atividade biológica, particularmente em produtos farmacêuticos. A presença do moiety benzofurano contribui para suas potenciais interações com alvos biológicos, enquanto o grupo fluorenilmetoxicarbonila (Fmoc) é comumente utilizado na síntese de peptídeos como um grupo protetor. O composto provavelmente exibirá características específicas de solubilidade, estabilidade sob certas condições e reatividade potencial devido aos seus grupos funcionais. Sua estrutura sugere aplicações potenciais em química medicinal, particularmente no desenvolvimento de terapias direcionadas a vias biológicas específicas. No entanto, estudos detalhados seriam necessários para elucidar completamente suas propriedades, incluindo sua farmacocinética, toxicidade e eficácia em sistemas biológicos.

Fórmula: C₃₄H₄₀N₄O₇S

InChI: InChI=1S/C34H40N4O7S/c1-19-20(2)30(21(3)26-17-34(4,5)45-29(19)26)46(42,43)38-32(35)36-16-10-15-28(31(39)40)37-33(41)44-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,37,41)(H,39,40)(H3,35,36,38)/t28-/m0/s1

Chave InChI: InChIKey=HNICLNKVURBTKV-NDEPHWFRSA-N

SMILES: C(OC(N[C@@H](CCCNC(NS(=O)(=O)C=1C(C)=C2C(=C(C)C1C)OC(C)(C)C2)=N)C(O)=O)=O)C3C=4C(C=5C3=CC=CC5)=CC=CC4

Sinónimos:

• (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-5-[N′-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido]pentanoic acid
• (E)-N~5~-(amino{[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]amino}methylidene)-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]ornithine
• <span class="text-smallcaps">L</span>-Ornithine, N⁵-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• FMOC-Arg(pbf)-OH
• FMOC-N-omega-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
• Fmoc-<span class="text-smallcaps">L</span>-Arg(Pbf)
• Fmoc-L-Arg(Pbf)-OH
• N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N5-{N-[(2,2,4,5,7-pentamethyl-2,3-dihydro-1-benzofuran-6-yl)sulfonyl]carbamimidoyl}-D-ornithine
• N⁵-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-ornithine
• Na-Fmoc-Nw-Pbf-L-arginine
• L-Ornithine, N5-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine

CAS: 154445-77-9

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 648.78

Ref: 3B-F0729

Nα-Fmoc-N^w-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzo[b]furan-5-ylsulfonyl)-L-arginine, 98%

CAS: 154445-77-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: 98%

Peso molecular: 648.78

Ref: 02-H59039

Fmoc-L-Arg(Pbf)-OH

CAS: 154445-77-9

M03398 - Fmoc-L-Arg(Pbf)-OH

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: 96 %

Cor e Forma: Crystalline Powder

Peso molecular: 648.78

Ref: 10-M03398

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Pbf protection is especially recommended for multiple-Arg- and Trp-containinng peptides. TFA cleavage is best performed in the presence of a silane scavenger.

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: 99.4081%

Cor e Forma: White

Peso molecular: 648.78

Ref: 01-4089151

FMOC-Arg(Pbf)-OH

CAS: 154445-77-9

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 648.7690

Ref: IN-DA0039MD

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Fmoc-Arg(Pbf)-OH

Pureza: 98%

Peso molecular: 648.77g/mol

Ref: 54-BI5913

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: ≥ 99.0%

Cor e Forma: White to almost white powder

Peso molecular: 648.77

Ref: 7W-GM9958

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Fmoc-Arg(Pbf)-OH is an amido-resin that is used in the industrial preparation of polyamides and as a reactive component for the synthesis of various peptide or protein drugs. The polymerisation reaction leads to the formation of a linear chain with a high molecular weight and low viscosity. Fmoc-Arg(Pbf)-OH has been used as an envisaged component for the synthesis of acetylcholine, messenger RNA, and nicotinic acetylcholine receptor. Trifluoroacetic acid is commonly used as a solvent in this process.

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: Min. 98.0 Area-%

Peso molecular: 648.77 g/mol

Ref: 3D-FLR-1746-PI

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

The Fmoc-Arg(Pbf)-OH is a cyclic peptide that has been shown to have significant cytotoxicity against human tumor cells. It binds to integrin receptors, which are involved in transcriptional regulation and cellular proliferation. The Fmoc-Arg(Pbf)-OH has been shown to be hypoglycemic and it also possesses redox potential. The chemical biology of this compound is not yet known, but toxicity studies have shown that it is nontoxic in mice.

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: Min. 98 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 648.77 g/mol

Ref: 3D-FF15787

Fmoc-Arg(Pbf)-OH

Produto Controlado

CAS: 154445-77-9

Applications Fmoc-Arg(Pbf)-OH, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

Fórmula: C₃₄H₄₀N₄O₇S

Cor e Forma: Neat

Peso molecular: 648.77

Ref: TR-F604100