CAS 155-41-9

(-)-Escopolamina metobrometo

Descrição:

(-)-Escopolamina metobrometo é um composto de amônio quaternário derivado da escopolamina, que é um alcaloide obtido de plantas como a estramônio e a beladona. Esta substância é caracterizada por sua capacidade de agir como um agente anticolinérgico, bloqueando principalmente a ação da acetilcolina nos receptores muscarínicos. É frequentemente utilizada em ambientes clínicos para prevenir o enjoo de movimento e para gerenciar os sintomas de salivação excessiva e secreções brônquicas. A forma de metobrometo melhora sua solubilidade e biodisponibilidade, tornando-a mais eficaz para uso terapêutico. Quimicamente, é conhecida por sua estrutura relativamente estável, que contribui para suas propriedades farmacológicas. O composto é tipicamente administrado por injeção ou por via oral, dependendo da indicação clínica. Seus efeitos colaterais podem incluir boca seca, visão turva e sonolência, que são comuns em medicamentos anticolinérgicos. No geral, (-)-Escopolamina metobrometo é um composto significativo na farmacologia, particularmente no manejo de condições relacionadas à atividade colinérgica hiperativa.

Fórmula: C₁₈H₂₄NO₄·Br

InChI: InChI=1S/C18H24NO4.BrH/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11;/h3-7,12-17,20H,8-10H2,1-2H3;1H/q+1;/p-1/t12-,13-,14-,15+,16-,17+;/m1./s1

Chave InChI: InChIKey=CXYRUNPLKGGUJF-RAFJPFSSSA-M

SMILES: C[N+]1(C)[C@@]2([C@]3([C@](O3)([C@]1(C[C@@H](OC([C@H](CO)C4=CC=CC=C4)=O)C2)[H])[H])[H])[H].[Br-]

Sinónimos:

• (-)-Scopolamine methyl bromide
• (1R,2R,4S,5S,7S)-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide
• (1S,5S)-7-[(3-hydroxy-2-phenylpropanoyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropanium, 6β,7β-epoxy-3α-hydroxy-8-methyl-, bromide, (-)-tropate
• 1αH,5αH-Tropanium, 6β,7β-epoxy-3α-hydroxy-8-methyl-, bromide, (-)-tropate
• 3-Oxa-9-azatricyclo[3.3.1.0^2,4]nonane, 3-oxa-9-azoniatricyclo[3.3.1.0^2,4]nonane deriv.
• 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9,9-dimethyl-, bromide, [7(S)-(1α,2β,4β,5α,7.beta]).-
• 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9,9-dimethyl-, bromide, [7(S)-(1α,2β,4β,5α,7β)]-
• 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-, bromide (1:1), (1α,2β,4β,5α,7β)-
• 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-, bromide, (1α,2β,4β,5α,7β)-
• 3-Oxa-9-azoniatricyclo[3.3.1.0^2,4]nonane, 7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9,9-dimethyl-, bromide, [7(S)-(1α,2β,4β,5α,7β)]-
• 3-Oxa-9-azoniatricyclo[3.3.1.0^2,4]nonane, 7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-, bromide (1:1), (1α,2β,4β,5α,7β)-
• 3-Oxa-9-azoniatricyclo[3.3.1.0^2,4]nonane, 7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-, bromide, (1α,2β,4β,5α,7β)-
• 7-{[(2R)-3-hydroxy-2-phenylpropanoyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide
• Ampyrox
• Blocan
• Bromure de N-methylhyoscinium
• Diopal
• Epoxymethamine bromide
• Epoxytropine tropate methylbromide
• Holopon
• Hyoscine methobromide
• Hyoscine methyl bromide
• Lescopine bromide
• Mescopil
• Methscopolamin bromide
• Methscopolamine bromide
• Methylscopolamine bromide
• N-Methylhyosciniumbromid
• N-Methylscopolamine bromide
• N-Methylscopolaminium bromide
• N-Methylscopolammonium bromide
• N-methylhyoscinium bromide
• Neo-Avagal
• Nsc 120606
• Nsc 61809
• Nutrop
• Pamine
• Pamine bromide
• Paraspan
• Proscomide
• Restropin
• Scopolamine methylbromide
• Tropic acid, (-), ester with 6β,7β-epoxy-3α-hydroxy-8-methyl-1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-tropanium bromide
• U 5036

Scopolamine Methyl Bromide

CAS: 13265-10-6, 155-41-9

Fórmula: C₁₈H₂₄BrNO₄

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 398.30

Ref: 3B-S0231

Scopolamine Methyl Bromide

CAS: 155-41-9

Fórmula: C₁₈H₂₄NO₄Br

Peso molecular: 318.40 : 79.90

Ref: ST-EA-CP-S114027

OXITROPIUM BROMIDE IMPURITY B CRS

CAS: 155-41-9

OXITROPIUM BROMIDE IMPURITY B CRS

Fórmula: C₁₈H₂₄BrNO₄

Peso molecular: 398.2915

Ref: 41-Y0000715

Methscopolamine Bromide (6β,7β-Epoxy-3α-hydroxy-8-methyl-1alphaH,5alphaH-tropanium bromide (-)-tropate)

CAS: 155-41-9

Other alkaloids,natural or reproduced by synthesis, and their salts, ethers,esters&other derivatives, nesoi

Fórmula: C₁₈H₂₄BrNO₄

Cor e Forma: White Crystalline Powder

Peso molecular: 397.08887

Ref: 45-1421009

Methscopolamine

CAS: 155-41-9

Methscopolamine (Hyoscine methyl bromide) (Pamine), as a natural plant alkaloid, is a muscarinic acetylcholine receptor blocker.

Fórmula: C₁₈H₂₄BrNO₄

Pureza: 99.12% - ≥98%

Cor e Forma: Solid

Peso molecular: 398.29

Ref: TM-T0253

Methscopolamine bromide

CAS: 155-41-9

Fórmula: C₁₈H₂₄BrNO₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 398.2915

Ref: IN-DA003RIA

Hyoscine Butylbromide EP Impurity C Bromide

CAS: 155-41-9

Fórmula: C₁₈H₂₄NO₄·Br

Cor e Forma: White To Off-White Solid

Peso molecular: 318.40 79.90

Ref: 4Z-S-0112

(-)-Scopolamine methyl bromide

CAS: 155-41-9

Fórmula: C₁₈H₂₄NO₄·Br

Peso molecular: 398.29

Ref: 7W-GK7168

(1R,2R,4S,5S,7s)-7-[[(2S)-3-Hydroxy-2-phenylpropanoyl]oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide (Methylhyoscine Bromide)

CAS: 155-41-9

Cor e Forma: Neat

Ref: 86-MM0792.04

Scopolamine Methyl Bromide

CAS: 155-41-9

Applications Scopolamine Methyl Bromide is the methylated derivative of Scopolamine (S200000), a muscarinic antagonist that is similar to acetylcholine. Scopolamine Methyl Bromide have been used for the treatment of peptic ulcers by reducing acid secretion of the stomach and is used to treat morning sickness.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Van Haaren, F., et al.: Pharmacol. Biochem. Behav., 32, 707 (1989); Marraccini, P., et al.: Abdom. Imaging., 21, 304 (1996);

Fórmula: C₁₈H₂₄NO₄·Br

Cor e Forma: Neat

Peso molecular: 398.29

Ref: TR-S200050

Methscopolamine bromide

CAS: 155-41-9

Methscopolamine bromide is a leukotriene receptor antagonist that is used to treat various conditions including bowel diseases and autoimmune diseases. Methscopolamine bromide binds to muscarinic receptors and blocks the action of acetylcholine, which mediates inflammation. Methscopolamine bromide can also be used to treat congestive heart failure. This drug has significant interactions with other medications, including thermal expansion, fatty acid metabolism, or symptoms of bowel disease. The drug should not be taken by patients who have had a stroke or who have asthma. It is contraindicated in patients who are pregnant or breastfeeding.

Fórmula: C₁₈H₂₄BrNO₄

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 398.29 g/mol

Ref: 3D-FM61567

Hyoscine Butylbromide EP Impurity C

CAS: 155-41-9

Fórmula: C₁₈H₂₄NO₄Br

Peso molecular: 318.39 : 79.9

Ref: ST-EA-CP-H6003