CAS 155148-31-5

1,1'-[1,4-Fenilenobis(metileno)]bis[1,4,8,11-tetraazaciclotetradecano]

Descrição:

1,1'-[1,4-Fenilenobis(metileno)]bis[1,4,8,11-tetraazaciclotetradecano], com número CAS 155148-31-5, é um composto orgânico complexo caracterizado por sua estrutura única que incorpora um grupo fenileno ligado por pontes de metileno a uma estrutura de tetraazaciclotetradecano. Este composto apresenta múltiplos átomos de nitrogênio dentro de sua estrutura cíclica, o que contribui para suas potenciais propriedades quelantes, permitindo-lhe formar complexos estáveis com íons metálicos. A presença do grupo fenileno melhora sua estabilidade e pode influenciar sua solubilidade e reatividade. Tipicamente, tais compostos são de interesse na química de coordenação e na ciência dos materiais, particularmente para aplicações em catálise, entrega de medicamentos ou como ligantes em estruturas metal-orgânicas. O componente tetraazaciclotetradecano sugere uma atividade biológica potencial, tornando-o um candidato para investigação adicional em química medicinal. No geral, as características estruturais do composto indicam uma natureza versátil, adequada para várias aplicações tanto em pesquisa acadêmica quanto em ambientes industriais.

Fórmula: C₂₈H₅₄N₈

InChI: InChI=1/C28H54N8.8ClH.2H2O/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36;;;;;;;;;;/h5-8,29-34H,1-4,9-26H2;8*1H;2*1H2

Chave InChI: InChIKey=UEUPDYPUTTUXLJ-UHFFFAOYSA-N

SMILES: C(C1=CC=C(CN2CCCNCCNCCCNCC2)C=C1)N3CCCNCCNCCCNCC3.Cl

Sinónimos:

• 1,1'-(Benzene-1,4-Diyldimethanediyl)Bis-1,4,8,11-Tetraazacyclotetradecane Octahydrochloride Dihydrate
• 1,1′-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] hydrochloride (1:8)
• 1,4,8,11-Tetraazacyclotetradecane, 1,1′-[1,4-phenylenebis(methylene)]bis-, hydrochloride (1:8)
• 1,4,8,11-Tetraazacyclotetradecane, 1,1′-[1,4-phenylenebis(methylene)]bis-, octahydrochloride
• AMD 3100 octahydrochloride
• Amd 3100
• Jm 3100
• Plerixafore 8HCl
• Sid 791
• Bicyclam
• JM3100, SID791, 1,1μ-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane octahydrochloride
• Plerixafor hcl
• amd3100 octahydrochloride hydrate
• Plerixafor 8HCl (AMD3100 8HCl)
• 1,1'-[1,4-PHENYLENEBIS(METHYLENE)]BIS-1,4,8,11-TETRAAZACYCLOTETRADECANE OCTAHYDROCHLORIDE
• Plerixafor 8HCl
• Plerixafor HCL(JM 3100)
• 1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane]
• JM3100
• AMD 3100 octahydrochloride, >=98%
• InSolution? CXCR4 Antagonist I, AMD3100
• Plerixafor (octahydrochloride)
• AMD 3100 octahydrochloride(8HCl)
• AMD3100 8HCl
• Plerixafor 8HCl (AMD3100)
• Plerixafor hydrochloride
• SID791 octahydrochloride
• AMD 3100 octahydroch
• Plerixafor hydrochloride salt
• Plerixafor Hydrochloride (1:8)
• Plerixafor 8HCl (AMD3100 8HCl) USP/EP/BP
• AMD3100 OCTAHYDROCHLORIDE
• Plerixafor(SynonyM: AMD3100 octahydrochloride hydrate)
• 1,4-Bis[(1,4,8,11-tetraazacyclotetradecan-1-yl)methyl]benzene Octahydrochloride
• AMD3100 HCl
• AMD3100 OCTAHYDROCHLORIDE;AMD-3100; AMD 3100
• CS-907
• BISCYCLAM
• CXCR4 Antagonist I, AMD3100
• AMD3100 hydrate octahydrochloride
• Plerixafor-d8 8HCl
• 1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride, min. 95 % (NMR)
• InSolution CXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem
• SID791
• AMD3100
• JM 3100 8HCl
• 1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride hydrate
• JM3100 octahydrochloride
• Plerixafor 8HCl (DB06809)
• AMD3100 OCTAHYDROCHLORIDE HYDRATE ANHYDROUS
• CXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem

AMD-3100 Octahydrochloride

CAS: 155148-31-5

Fórmula: C₂₈H₅₄N₈·8HCl

Pureza: >98.0%(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 794.46

Ref: 3B-P2620

1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-, hydrochloride (1:8)

CAS: 155148-31-5

Fórmula: C₂₈H₆₂Cl₈N₈

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 794.4695

Ref: IN-DA001NNI

AMD3100 octahydrochloride hydrate

CAS: 155148-31-5

Fórmula: C₂₈H₅₄N₈·8HCl·xH₂O

Pureza: ≥ 97.0% (anhydrous basis)

Cor e Forma: White or off-white powder

Peso molecular: 794.47 (anhydrous)

Ref: 7W-GK7176

Plerixafor octahydrochloride

CAS: 155148-31-5

Plerixafor octahydrochloride

Pureza: ≥95%

Peso molecular: 794.46g/mol

Ref: 54-BUP13171

Plerixafor-d8 8HCl

CAS: 155148-31-5

Fórmula: C₂₈H₄₆D₈N₈·8HCl

Cor e Forma: White To Off-White Solid

Peso molecular: 510.84 8 36.46

Ref: 4Z-P-557

Plerixafor 8HCl

CAS: 155148-31-5

Fórmula: C₂₈H₅₄N₈·8HCl

Cor e Forma: White To Off-White Solid

Peso molecular: 502.80 8 36.46

Ref: 4Z-P-551

1,4-Bis((1,4,8,11-Tetraazacyclotetradecan-1-Yl)Methyl)Benzene Octahydrochloride

CAS: 155148-31-5

1,4-Bis((1,4,8,11-Tetraazacyclotetradecan-1-Yl)Methyl)Benzene Octahydrochloride

Pureza: 99%

Peso molecular: 794.47g/mol

Ref: 54-OR1009221

Plerixafor octahydrochloride

CAS: 155148-31-5

Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.

Fórmula: C₂₈H₆₂Cl₈N₈

Pureza: 98.01% - 99.79%

Cor e Forma: Solid

Peso molecular: 794.46

Ref: TM-T1776L

AMD 3100 octahydrochloride

CAS: 155148-31-5

Antagonises CXCR4 selectively by blocking Ca2+ release (IC50 from 0.02 to 0.13 µM). Studied in SDF-1/CFXCR4-dependent functions in HIV, rheumatoid arthritis and breast cancer metastasis. Enhances mobilization of hematopoietic stem cells (HSCs) and Hematopoietic progenitor cells (HPCs) for re-populating hematopoietic progenitors for transplants in vivo and attenuates cocaine-induced locomotor activation.

Fórmula: C₂₈H₆₂Cl₈N₈

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 794.47 g/mol

Ref: 3D-FA148913

Plerixafor octahydrochloride

CAS: 155148-31-5

Pureza: 99%

Peso molecular: 794.46

Ref: 10-F979582

Plerixafor Hydrochloride (1:8)

Produto Controlado

CAS: 155148-31-5

Stability Hygroscopic
Applications Plerixafor Hydrochloride (1:8), is an immunostimulant used to mobilize hematopoietic stem cells in cancer patients. It is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α).
References Xie, T., et al.: Science, 290, 328 (2000), Leone, D., et al.: J. Pharmacol. Exp. Ther., 305, 1150 (2003), Chigaev, A., et al.: J. Immunol. 178, 6828 (2007), Kiel, M., et al.: Cell Stem Cell, 1, 204 (2007),

Fórmula: C₂₈H₅₄N₈·8ClH

Cor e Forma: Neat

Peso molecular: 794.47

Ref: TR-P580505