CAS 155206-00-1

Bimatoprosta

Descrição:

Bimatoprosta é um análogo sintético de prostaglandina usado principalmente em oftalmologia para o tratamento do glaucoma e da hipertensão ocular. Funciona aumentando o escoamento do humor aquoso, reduzindo assim a pressão intraocular. A estrutura química de Bimatoprosta apresenta uma longa cadeia hidrocarbônica com um grupo ácido carboxílico, que contribui para sua atividade biológica. É tipicamente administrado como uma solução em gotas para os olhos e é conhecido por sua eficácia em promover o crescimento dos cílios, levando ao seu uso em aplicações cosméticas também. Bimatoprosta tem um peso molecular relativamente baixo e é lipofílico, permitindo que penetre eficazmente nas membranas biológicas. Sua farmacocinética envolve rápida absorção e metabolismo, com uma meia-vida que apoia seu uso terapêutico. Os efeitos colaterais podem incluir hiperemia ocular, irritação ocular e alterações na pigmentação dos cílios. No geral, Bimatoprosta é um composto versátil com aplicações significativas nos campos médico e cosmético.

Fórmula: C₂₅H₃₇NO₄

InChI: InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1

Chave InChI: InChIKey=AQOKCDNYWBIDND-FTOWTWDKSA-N

SMILES: C(=C/[C@H](CCC1=CC=CC=C1)O)\[C@@H]2[C@@H](C/C=C\CCCC(NCC)=O)[C@@H](O)C[C@H]2O

Sinónimos:

• (5E)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide
• (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide
• (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide
• (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
• 17-Phenyl-Tri-Norprostaglandin F2Α-Ethyl Amide
• 17-Phenyltrinor-PGF2α ethylamide
• 17-phenyl TRINOR prostaglandin F2ALPHA ethyl amide
• 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-, (5Z)-
• 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-N-ethyl-, (5Z)-
• 5-Heptenamide, 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl]-N-ethyl-, [1R-[1α(Z),2β(1E,3S*),3α,5α]]-
• Agn 192024
• Bimatoprost(LUMIGAN)
• Bimatoprost(TM)
• Latisse
• Lumigan
• N-Ethyl-9Alpha,11Alpha,15S-Trihydroxy-17-Phenyl-18,19,20-Trinor-Prosta-5Z, 13E-Dien-1-Amide
• Prostamide

Bimatoprost

CAS: 155206-00-1

Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analogues

Fórmula: C₂₅H₃₇NO₄

Cor e Forma: White Off-White Powder

Peso molecular: 415.27226

Ref: 45-1071348

5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-, (5Z)-

CAS: 155206-00-1

Fórmula: C₂₅H₃₇NO₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 415.5656

Ref: IN-DA001NQ8

Bimatoprost

CAS: 155206-00-1

Bimatoprost

Pureza: ≥98%

Peso molecular: 415.57g/mol

Ref: 54-BUP09673

Bimatoprost, min. 98%

CAS: 155206-00-1

Fórmula: C₂₅H₃₇NO₄

Pureza: min. 98%

Cor e Forma: White to Off-white Powder

Peso molecular: 415.57

Ref: 08-06-6008

Bimatoprost

CAS: 155206-00-1

Bimatoprost

Pureza: 99%

Peso molecular: 415.57g/mol

Ref: 54-OR1025538

Bimatoprost

CAS: 155206-00-1

Fórmula: C₂₅H₃₇NO₄

Cor e Forma: White To Off-White Solid

Peso molecular: 415.57

Ref: 4Z-B-241

Bimatoprost

CAS: 155206-00-1

Fórmula: C₂₅H₃₇NO₄

Pureza: ≥ 97.0%

Cor e Forma: White or off-white crystalline powder or crystals

Peso molecular: 415.57

Ref: 7W-GX7154

Bimatoprost-d5

CAS: 155206-00-1

Fórmula: C₂₅H₃₂D₅NO₄

Peso molecular: 420.60

Ref: 4Z-B-242

Bimatoprost

CAS: 155206-00-1

Fórmula: C₂₅H₃₇NO₄

Cor e Forma: Neat

Peso molecular: 415.57

Ref: 86-MM3603.00

Bimatoprost Impurity 14

CAS: 155206-00-1

Fórmula: C₃₅H₅₃NO₆

Peso molecular: 583.81

Ref: 4Z-B-2422

Bimatoprost

CAS: 155206-00-1

Bimatoprost (AGN 192024) is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular

Fórmula: C₂₅H₃₇NO₄

Pureza: 98% - >99.99%

Cor e Forma: Crystalline Solid

Peso molecular: 415.57

Ref: TM-T2538

Bimatoprost

CAS: 155206-00-1

Stability Light Sensitive
Applications Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α.
References Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001), Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003), Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004),

Fórmula: C₂₅H₃₇NO₄

Cor e Forma: White

Peso molecular: 415.57

Ref: TR-B386800

Bimatoprost-d5

Produto Controlado

CAS: 155206-00-1

Applications Labelled Bimatoprost (B386800). Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α.
References Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001), Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003), Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004),

Fórmula: C₂₅H₃₂D₅NO₄

Cor e Forma: Neat

Peso molecular: 420.6

Ref: TR-B386802

Bimatoprost

CAS: 155206-00-1

A potent prostanoid receptor (FP) agonist and PGF2α analog. Its biological activity is mediated by action on prostamide receptors. Has therapeutic potential for glaucoma and ocular hypertension.

Fórmula: C₂₅H₃₇NO₄

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 415.57 g/mol

Ref: 3D-FB18599

Bimatoprost

CAS: 155206-00-1

Fórmula: C₂₅H₃₇NO₄

Pureza: >98.0%(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 415.57

Ref: 3B-B6165

BIMATOPROST

CAS: 155206-00-1

Pureza: 99%

Peso molecular: 415.5740051

Ref: 10-F794030

Bimatoprost Acid Ethyl Ester

Produto Controlado

CAS: 155206-00-1

Applications Bimatoprost Acid Ethyl Ester is an impurity of Bimatoprost (B386800). Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α.
References Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001), Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003), Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004),

Fórmula: C₂₅H₃₆O₅

Cor e Forma: Neat

Peso molecular: 416.55

Ref: TR-B386875