CAS 15671-27-9

Sulfito de cobalamina

Descrição:

Sulfito de cobalamina, com o número CAS 15671-27-9, é um derivado da vitamina B12, especificamente uma forma de cobalamina que contém um grupo sulfonato. É caracterizado por sua complexa estrutura centrada em cobalto, que é essencial para sua atividade biológica. Este composto é tipicamente um sólido cristalino de cor vermelho-púrpura, refletindo a cor característica dos derivados de cobalamina. Sulfito de cobalamina é solúvel em água, o que facilita seu uso em várias aplicações bioquímicas, particularmente no tratamento da deficiência de vitamina B12. Sua estabilidade pode ser influenciada por fatores como pH e exposição à luz, tornando as condições de armazenamento adequadas cruciais. Em sistemas biológicos, Sulfito de cobalamina pode participar de reações enzimáticas, contribuindo para processos como a síntese de DNA e a formação de glóbulos vermelhos. Além disso, pode servir como uma fonte de cobalto biodisponível, que é vital para numerosas funções enzimáticas. No geral, Sulfito de cobalamina desempenha um papel significativo na nutrição e bioquímica, particularmente em relação ao metabolismo celular e à produção de energia.

Fórmula: C₆₂H₈₉CoN₁₃O₁₇PS

InChI: InChI=1S/C62H90N13O14P.Co.H2O3S/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;1-4(2)3/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;(H2,1,2,3)/q;+3;/p-3

Chave InChI: InChIKey=IUJJHFFFUXMHFY-UHFFFAOYSA-K

SMILES: [O-](S(=O)O)[Co+3]1234[N]=5C6(C)C7[N-]1C(C(C)(C7CC(N)=O)CCC(=O)NCC(C)OP(=O)([O-])OC8C(O)C(N9C=[N]2C=%10C9=CC(C)=C(C)C%10)OC8CO)=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5C(CCC(N)=O)C6(CC(N)=O)C)C(CC(N)=O)(C)C%12CCC(N)=O)C(C)(C)C%11CCC(N)=O

Sinónimos:

• Cobalamin, sulfito-
• Cobalaminsulfonic acid
• Cobinamide, Co-(sulfito-κO)-, dihydrogen phosphate (ester), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³)
• Cobinamide, hydroxide sulfite (1:1) (salt), dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
• Cobinamide, sulfite (1:1) (salt), dihydrogen phosphate (ester), 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
• Cobinamide, sulfite (1:1) (salt), dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
• Cobinamide, sulfite phosphate, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
• Sulfiotcobalamine
• Sulfitocobalamin
• Vitamin B₁₂-sulfonic acid
• Cobinamide, Co-(sulfito-κO)-, dihydrogen phosphate (ester), inner salt, 3′-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3)
• Cobinamide, sulfite phosphate, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole
• Cobinamide, hydroxide sulfite (1:1) (salt), dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
• Cobinamide, sulfite (1:1) (salt), dihydrogen phosphate (ester), 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole

Sulphitocobalamin

CAS: 15671-27-9

Fórmula: C₆₂H₈₈CoN₁₃O₁₄P·HO₃S

Peso molecular: 1329.38 81.07

Ref: 4Z-V-035003

Sulfitocobalamin Sodium Salt

CAS: 15671-27-9

Applications Sulfitocobalamin Sodium Salt is a useful synthetic intermediate in the synthesis of Hydroxocobalamin Acetate (H826800); a physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic).
References Kaczka, E.A., et al.: Science, 112, 354 (1950); Friedrich, W., et al.: Vitamins, 837 (1988); Forsyth, J.C., et al.: Clin. Toxicol., 31, 277 (1993)

Fórmula: C₆₂H₈₈CoN₁₃NaO₁₇PS

Cor e Forma: Neat

Peso molecular: 1432.4

Ref: TR-S699360

Sulfitocobalamin sodium salt

CAS: 15671-27-9

Sulfitocobalamin sodium salt is a bacterial strain that is used as a probiotic. It has been shown to be biocompatible and can be used with human liver cells in laboratory studies. Sulfitocobalamin sodium salt is also effective in treating bowel disease, because it reduces the inflammatory response by inhibiting pro-inflammatory cytokine production and preventing the damage of mucosal cells. Sulfitocobalamin sodium salt has been shown to inhibit growth of infectious bacteria, such as Salmonella enterica serovar Typhimurium and Helicobacter pylori, which cause diseases like hepatitis and corrinosis. The molecule also has biological properties that are used for the treatment of inflammation, ulcerative colitis, and other diseases caused by infectious agents.

Fórmula: C₆₂H₈₈CoN₁₃NaO₁₇PS

Pureza: Min. 95%

Peso molecular: 1,432.4 g/mol

Ref: 3D-FS173315

Sulphitocobalamin

CAS: 15671-27-9

Fórmula: C₆₂H₈₈CoN₁₃O₁₄PHO₃S

Peso molecular: 1329.38 : 81.07

Ref: ST-EA-CP-H13003