![(6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F28043-6r-7r-7-amino-3-hydroxymethyl-8-oxo-5-thia-1-azabicyclo-4-2-0-oct-2-ene-2-carboxylic-acid.webp&w=3840&q=75)
CAS 15690-38-7
:ácido (6R,7R)-7-amino-3-(hidroximetil)-8-oxo-5-tia-1-azabiciclo[4.2.0]oct-2-eno-2-carboxílico
Descrição:
A substância química conhecida como ácido (6R,7R)-7-amino-3-(hidroximetil)-8-oxo-5-tia-1-azabiciclo[4.2.0]oct-2-eno-2-carboxílico, com o número CAS 15690-38-7, é um composto bicíclico que apresenta uma estrutura de anel de tiazolidina. Este composto é caracterizado pela presença de um grupo amino, um grupo hidroximetílico e um grupo funcional ácido carboxílico, contribuindo para sua potencial atividade biológica. A estereoquímica indicada pela configuração (6R,7R) sugere arranjos espaciais específicos de átomos que podem influenciar as interações do composto com alvos biológicos. Seu grupo oxo e o componente tiazolidina sugerem reatividade potencial e interações com vários sistemas biológicos. Este composto é de interesse na química medicinal, particularmente no desenvolvimento de antibióticos, devido às suas semelhanças estruturais com agentes antibióticos conhecidos. A estrutura bicíclica única também pode conferir propriedades farmacológicas específicas, tornando-o um assunto de pesquisa em design e desenvolvimento de medicamentos.
Fórmula:C8H10N2O4S
InChI:InChI=1S/C8H10N2O4S/c9-4-6(12)10-5(8(13)14)3(1-11)2-15-7(4)10/h4,7,11H,1-2,9H2,(H,13,14)/t4-,7-/m1/s1
Chave InChI:InChIKey=BQIMPGFMMOZASS-CLZZGJSISA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@H](N)C2=O)(SCC1CO)[H]
Sinónimos:- (6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- (6R,7R)-7-Amino-3-hydroxymethylceph-3-em-4-carboxylic acid
- 3-Hydroxymethyl-7-aminoceph-3-em-4-carboxylic acid
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, (6R-trans)-
- 7-Amino-3-(Hydroxymethyl)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
- 7-Amino-3-hydoxymethyl-3-cephem-carboxylic acid
- 7-Amino-3-hydroxymethyl-3-cephem-4-carboxylic acid
- 7-Amino-deacetylcephalosporanic acid
- 7β-Amino-3-(hydroxymethyl)-3-cephem-4-carboxylic acid
- Deacetyl-7-aminocephalosporanic acid
- Ver mais sinónimos
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9 produtos.
(6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS:Fórmula:C8H10N2O4SPureza:95%Cor e Forma:SolidPeso molecular:230.2410(6R,7R)-7-Amino-3-Hydroxymethyl-8-Oxo-5-Thia-1-Aza-Bicyclo[4.2.0.]Oct-2-Ene-2-Carboxylic Acid
CAS:(6R,7R)-7-Amino-3-Hydroxymethyl-8-Oxo-5-Thia-1-Aza-Bicyclo[4.2.0.]Oct-2-Ene-2-Carboxylic AcidPureza:98%Peso molecular:230.24g/molDeacetyl-7-aminocephalosporanic acid
CAS:Deacetyl-7-aminocephalosporanic acid serves as a crucial intermediate in the production of β-lactam broad-spectrum cephalosporin antibiotics.Fórmula:C8H10N2O4SPureza:99.97%Cor e Forma:SolidPeso molecular:230.247-Aminodeacetylcephalosporanic Acid
CAS:Fórmula:C8H10N2O4SPureza:>97.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:230.247-Amino-deacetylcephalosporanic Acid
CAS:Produto ControladoApplications Intermediate in the semi-synthetic cephalosporins synthesis. Found in Acremonium chrysogenum.
References Fukagawa, M. et al.; Agr. Biol. Chem. 55, 2163 (1991)Fórmula:C8H10N2O4SCor e Forma:NeatPeso molecular:230.24(6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS:Fórmula:C8H10N2O4SPureza:95%Cor e Forma:SolidPeso molecular:230.247-Amino-3-(hydroxymethyl)-cephem-4-carboxylic acid
CAS:Cefepime is a broad-spectrum antibiotic that belongs to the group of β-lactam antibiotics. It inhibits the growth of bacteria by binding to the 50S ribosomal subunit, which prevents bacterial protein synthesis. Cefepime hydrochloride is a prodrug that is hydrolyzed in vivo to cefepime, its active form. Cefepime hydrochloride has been shown to inhibit the production of subtilisin and acylase, enzymes involved in the digestion of proteins and fats. The hydrolysis reaction also increases the solubility of cefepime. The crystallization process for cefepime hydrochloride involves heating with organic solvents such as methanol and ethanol. This process can be used for purification and isolation from impurities.Fórmula:C8H10N2O4SPureza:Min. 95%Peso molecular:230.24 g/mol
![(6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA007HQ7.jpg&w=3840&q=75)
![(6R,7R)-7-Amino-3-Hydroxymethyl-8-Oxo-5-Thia-1-Aza-Bicyclo[4.2.0.]Oct-2-Ene-2-Carboxylic Acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FOR1029784.jpg&w=3840&q=75)
![(6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF243053.jpg&w=3840&q=75)
