CAS 15690-38-7

ácido (6R,7R)-7-amino-3-(hidroximetil)-8-oxo-5-tia-1-azabiciclo[4.2.0]oct-2-eno-2-carboxílico

Descrição:

A substância química conhecida como ácido (6R,7R)-7-amino-3-(hidroximetil)-8-oxo-5-tia-1-azabiciclo[4.2.0]oct-2-eno-2-carboxílico, com o número CAS 15690-38-7, é um composto bicíclico que apresenta uma estrutura de anel de tiazolidina. Este composto é caracterizado pela presença de um grupo amino, um grupo hidroximetílico e um grupo funcional ácido carboxílico, contribuindo para sua potencial atividade biológica. A estereoquímica indicada pela configuração (6R,7R) sugere arranjos espaciais específicos de átomos que podem influenciar as interações do composto com alvos biológicos. Seu grupo oxo e o componente tiazolidina sugerem reatividade potencial e interações com vários sistemas biológicos. Este composto é de interesse na química medicinal, particularmente no desenvolvimento de antibióticos, devido às suas semelhanças estruturais com agentes antibióticos conhecidos. A estrutura bicíclica única também pode conferir propriedades farmacológicas específicas, tornando-o um assunto de pesquisa em design e desenvolvimento de medicamentos.

Fórmula: C₈H₁₀N₂O₄S

InChI: InChI=1S/C8H10N2O4S/c9-4-6(12)10-5(8(13)14)3(1-11)2-15-7(4)10/h4,7,11H,1-2,9H2,(H,13,14)/t4-,7-/m1/s1

Chave InChI: InChIKey=BQIMPGFMMOZASS-CLZZGJSISA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](N)C2=O)(SCC1CO)[H]

Sinónimos:

• (6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-Amino-3-hydroxymethylceph-3-em-4-carboxylic acid
• 3-Hydroxymethyl-7-aminoceph-3-em-4-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, (6R-trans)-
• 7-Amino-3-(Hydroxymethyl)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
• 7-Amino-3-hydoxymethyl-3-cephem-carboxylic acid
• 7-Amino-3-hydroxymethyl-3-cephem-4-carboxylic acid
• 7-Amino-deacetylcephalosporanic acid
• 7β-Amino-3-(hydroxymethyl)-3-cephem-4-carboxylic acid
• Deacetyl-7-aminocephalosporanic acid

(6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CAS: 15690-38-7

Fórmula: C₈H₁₀N₂O₄S

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 230.2410

Ref: IN-DA007HQ7

(6R,7R)-7-Amino-3-Hydroxymethyl-8-Oxo-5-Thia-1-Aza-Bicyclo[4.2.0.]Oct-2-Ene-2-Carboxylic Acid

CAS: 15690-38-7

(6R,7R)-7-Amino-3-Hydroxymethyl-8-Oxo-5-Thia-1-Aza-Bicyclo[4.2.0.]Oct-2-Ene-2-Carboxylic Acid

Pureza: 98%

Peso molecular: 230.24g/mol

Ref: 54-OR1029784

Cefazedone Impurity 11

CAS: 15690-38-7

Fórmula: C₈H₁₀N₂O₄S

Cor e Forma: Off-White Solid

Peso molecular: 230.24

Ref: 4Z-C-108012

Deacetyl-7-aminocephalosporanic acid

CAS: 15690-38-7

Deacetyl-7-aminocephalosporanic acid serves as a crucial intermediate in the production of β-lactam broad-spectrum cephalosporin antibiotics.

Fórmula: C₈H₁₀N₂O₄S

Pureza: 99.97%

Cor e Forma: Solid

Peso molecular: 230.24

Ref: TM-T21006

7-Aminodeacetylcephalosporanic Acid

CAS: 15690-38-7

Fórmula: C₈H₁₀N₂O₄S

Pureza: >97.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 230.24

Ref: 3B-A2878

7-Amino-deacetylcephalosporanic Acid

Produto Controlado

CAS: 15690-38-7

Applications Intermediate in the semi-synthetic cephalosporins synthesis. Found in Acremonium chrysogenum.
References Fukagawa, M. et al.; Agr. Biol. Chem. 55, 2163 (1991)

Fórmula: C₈H₁₀N₂O₄S

Cor e Forma: Neat

Peso molecular: 230.24

Ref: TR-A603420

(6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CAS: 15690-38-7

Pureza: 95.0%

Cor e Forma: Solid

Peso molecular: 230.24000549316406

Ref: 10-F243053

Cefazedone Impurity 1

CAS: 15690-38-7

Fórmula: C₈H₁₀N₂O₄S

Peso molecular: 230.24

Ref: ST-EA-CP-C209001

7-Amino-3-(hydroxymethyl)-cephem-4-carboxylic acid

CAS: 15690-38-7

Cefepime is a broad-spectrum antibiotic that belongs to the group of β-lactam antibiotics. It inhibits the growth of bacteria by binding to the 50S ribosomal subunit, which prevents bacterial protein synthesis. Cefepime hydrochloride is a prodrug that is hydrolyzed in vivo to cefepime, its active form. Cefepime hydrochloride has been shown to inhibit the production of subtilisin and acylase, enzymes involved in the digestion of proteins and fats. The hydrolysis reaction also increases the solubility of cefepime. The crystallization process for cefepime hydrochloride involves heating with organic solvents such as methanol and ethanol. This process can be used for purification and isolation from impurities.

Fórmula: C₈H₁₀N₂O₄S

Pureza: Min. 95%

Peso molecular: 230.24 g/mol

Ref: 3D-FA36388