CAS 15761-39-4

BOC-L-Prolina

Descrição:

BOC-L-Prolina, com o número CAS 15761-39-4, é um derivado do aminoácido prolina, caracterizado pela presença de um grupo protetor de tert-butiloxicarbonila (BOC). Este composto é comumente utilizado na síntese de peptídeos como um grupo protetor para o grupo amino da prolina, facilitando a formação de ligações peptídicas sem reações secundárias indesejadas. BOC-L-Prolina é tipicamente um sólido cristalino branco a off-white, e é solúvel em solventes orgânicos como diclorometano e dimetilformamida, mas menos solúvel em água. O grupo BOC é facilmente removido em condições ácidas, permitindo a regeneração do grupo amino livre para reações posteriores. Este composto desempenha um papel significativo na síntese de vários peptídeos e produtos farmacêuticos, tornando-o valioso na química medicinal e bioquímica. Sua estabilidade, facilidade de manuseio e compatibilidade com várias condições de reação contribuem para seu uso generalizado na química orgânica sintética.

Fórmula: C₁₀H₁₇NO₄

InChI: InChI=1/C10H17NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)/p-1/t7-/m0/s1

Chave InChI: InChIKey=ZQEBQGAAWMOMAI-ZETCQYMHSA-N

SMILES: C(OC(C)(C)C)(=O)N1[C@H](C(O)=O)CCC1

Sinónimos:

• (2S)-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester
• (2S)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylate
• (2S)-1-Boc-pyrrolidine-2-carboxylic acid
• (2S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
• (2S)-1-tert-Butoxycarbonylpyrrolidine-2-carboxylic acid
• (S)-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester
• (S)-1-(tert-Butoxycarbonyl)-2-pyrrolidinecarboxylic acid
• (S)-1-Boc-β-proline
• (S)-N-tert-Butoxycarbonylproline
• (S)-Pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
• 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)-
• 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (S)-
• 1,2-Pyrrolidinedicarboxylic acid, 1-tert-butyl ester, <span class="text-smallcaps">L</span>-
• 1,2-Pyrrolidinedicarboxylic acid, 1-tert-butyl ester, L-
• 1-(Tert-Butoxycarbonyl)Proline
• 1-(tert-Butoxycarbonyl)-(2S)-pyrrolidine-2-carboxylic acid
• 1-(tert-Butoxycarbonyl)-(S)-proline
• 1-(tert-Butyl)hydrogen-(S)-pyrrolidin-1,2-dicarboxylat
• 1-(tert-butoxycarbonyl)-L-proline
• 1-(tert-butyl) hydrogen (S)-pyrrolidine-1,2-dicarboxylate
• 1-Boc-L-Proline
• 1-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-proline
• 1-tert-Butyl (S)-pyrrolidine-1,2-dicarboxylate
• 1-tert-Butyloxycarbonyl-<span class="text-smallcaps">L</span>-proline
• 1-tert-Butyloxycarbonyl-L-proline
• <span class="text-smallcaps">L</span>-N-Boc-proline
• BOC-<span class="text-smallcaps">L</span>-Proline
• Boc-<span class="text-smallcaps">L</span>-Pro
• Boc-L-Pro-OH
• Boc-Pro-OH
• Hydrogeno-(S)-pyrrolidine-1,2-dicarboxylate de 1-(tert-butyle)
• L-N-Boc-proline
• N-(t-Butoxycarbonyl)proline
• N-(tert-Butoxycarbonyl)-(S)-proline
• N-(tert-Butoxycarbonyl)-<span class="text-smallcaps">L</span>-proline
• N-(tert-Butoxycarbonyl)-L-proline
• N-(tert-Butoxycarbonyl)proline
• N-(tert-Butyloxycarbonyl)-<span class="text-smallcaps">L</span>-proline
• N-(tert-Butyloxycarbonyl)-L-proline
• N-Boc-(S)-proline
• N-Boc-<span class="text-smallcaps">L</span>-proline
• N-Boc-L-proline
• N-[(1,1-Dimethylethoxy)carbonyl]-(S)-proline
• N-alpha-tert-BOC-L-proline
• Nsc 164660
• hidrogeno-(S)-pirrolidina-1,2-dicarboxilato de 1-(terc-butilo)
• tert-Butoxycarbonyl-L-proline
• tert-Butyloxycarbonyl-L-proline
• trans-N-(tert-Butoxycarbonyl)-4-hydroxy-<span class="text-smallcaps">L</span>-proline
• BOC-L-PROLINE-OH
• N-ALPHA-T-BUTOXYCARBONYL-L-PROLINE
• BOC-L-PRO
• N-ALPHA-TERT-BUTYLOXYCARBONYL-L-PROLINE
• N-T-BOC-L-PROLINE
• BOC-L-PROLINE
• N-ALPHA-T-BOC-L-PROLINE
• BOC-PRO
• N-T-BUTOXYCARBONYL-L-PROLINE
• BOC-PYRD(2)-OH
• N-(TERT-BUTOXYCARBONYL)-L-PROILNE
• N-ALPHA-T-BUTOXYCARBONYL-L-PYRROLIDINE-2-CARBOXYLIC ACID

N-(tert-Butoxycarbonyl)-L-proline

CAS: 15761-39-4

Fórmula: C₁₀H₁₇NO₄

Pureza: >99.0%(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 215.25

Ref: 3B-B1188

N-Boc-L-proline, 99%

CAS: 15761-39-4

N-Boc-L-proline is used as an intermediate in organic synthesis. It is also used to prepare daclatasvir, which inhibits the hepatitis C virus (HCV) non-structural 5A (NS5A) protein. Further, it is used as a drug in the treatment of hepatitis C virus (HCV). This Thermo Scientific Chemicals brand prod

Fórmula: C₁₀H₁₇NO₄

Pureza: 99%

Cor e Forma: Crystals or powder or crystalline powder, White

Peso molecular: 215.25

Ref: 02-A13744

Boc-Pro-OH

CAS: 15761-39-4

Bachem ID: 4000220.

Fórmula: C₁₀H₁₇NO₄

Pureza: > 99%

Cor e Forma: White

Peso molecular: 215.25

Ref: 01-4000220

N-(tert-Butoxycarbonyl)-L-proline

CAS: 15761-39-4

Fórmula: C₁₀H₁₇NO₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 215.2463

Ref: IN-DA003OI7

Boc-Pro-OH

CAS: 15761-39-4

Fórmula: C₁₀H₁₇NO₄

Peso molecular: 215.25

Ref: 7W-GM0659

(2S)-Pyrrolidine-2-carboxylic acid, N-BOC protected

CAS: 15761-39-4

(2S)-Pyrrolidine-2-carboxylic acid, N-BOC protected

Fórmula: C₁₀H₁₇NO₄

Pureza: 99%

Cor e Forma: white solid

Peso molecular: 215.25g/mol

Ref: 54-OR61282

Boc-Pro-OH

CAS: 15761-39-4

M03314 - Boc-Pro-OH

Fórmula: C₁₀H₁₇NO₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 215.249

Ref: 10-M03314

N-Boc-L-proline

CAS: 15761-39-4

Fórmula: C₁₀H₁₇NO₄

Peso molecular: 215.25

Ref: 4Z-P-166059

N-Boc-L-proline

Produto Controlado

CAS: 15761-39-4

Applications N-Boc-L-proline is a useful synthetic intermediate. It is used to synthesize Daclatasvir (D101500) which nhibits the HCV protein NS5A. Daclatasvir (D101500) can be used as a drug candidate for the treatment of hepatitis C (HCV).
References Gao, M., et al.: Nature, 465(7294), 96 (2010); Bell, T. W., Chem. Med. Chem., 5(10), 1663 (2010);

Fórmula: C₁₀H₁₇NO₄

Cor e Forma: Neat

Peso molecular: 215.25

Ref: TR-B664200

BOC-L-Proline extrapure, 99%

CAS: 15761-39-4

Fórmula: C₁₀H₁₇NO₄

Pureza: min. 99%

Cor e Forma: White, Crystalline powder

Peso molecular: 215.30

Ref: SR-91894

N-(tert-Butoxycarbonyl)-L-proline

CAS: 15761-39-4

Fórmula: C₁₀H₁₇NO₄

Peso molecular: 215.2

Ref: ST-EA-CP-D71018

N-Boc-L-proline

CAS: 15761-39-4

N-Boc-L-proline is a proline derivative that has been synthesized as a drug candidate for cancer treatment. It has been shown to inhibit the activity of the enzyme, buserelin, which is involved in the synthesis of histamine and other substances. N-Boc-L-proline has also been shown to cause neuronal death by hydrogen bond formation with nitrogen nucleophiles in the brain, leading to apoptosis. The chromatographic method was used to analyze reaction products from N-Boc-L-proline with sodium carbonate. This compound has solubility data and an intramolecular hydrogen bond that can be detected by nmr spectroscopy. Trifluoroacetic acid was used as a solvent for this experiment.

Fórmula: C₁₀H₁₇NO₄

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 215.25 g/mol

Ref: 3D-FB11370

Boc-Pro-OH

CAS: 15761-39-4

Boc-Pro-OH is a synthetic amino acid that is used in the preparation of samples for gas chromatography. Boc-Pro-OH has antiinflammatory activity, and can be used to treat cancer. It is also used as an intermediate in the synthesis of amides, which are important in pharmaceuticals. Boc-Pro-OH is soluble in water and carbonate buffer solutions, but insoluble in ethanol. The chemical structure of this molecule is unusual because it contains a Boc group.

Fórmula: C₁₀H₁₇NO₄

Pureza: Min. 95%

Peso molecular: 215.25 g/mol

Ref: 3D-BLP-2056