CAS 158442-41-2

N-cbz-ile-glu(O-T-butil)-ala-leucinal

Descrição:

N-cbz-ile-glu(O-T-butil)-ala-leucinal, com o número CAS 158442-41-2, é um composto sintético que pertence à classe de peptídeos e derivados de peptídeos. Apresenta um grupo protetor Cbz (benzyloxycarbonyl), que é comumente usado na síntese de peptídeos para proteger o grupo amino do aminoácido. O composto contém isoleucina (ile), ácido glutâmico (glu) com uma modificação de éster tert-butilo, alanina (ala) e leucina (leucinal), indicando uma estrutura complexa que pode exibir atividades biológicas específicas. A presença do grupo tert-butilo aumenta a lipofilicidade do resíduo de ácido glutâmico, potencialmente influenciando a solubilidade e permeabilidade do composto. Este composto pode ser de interesse em química medicinal e desenvolvimento de medicamentos, particularmente no design de terapias baseadas em peptídeos. Suas características, incluindo estabilidade, reatividade e atividade biológica, dependeriam do contexto específico de seu uso e das condições sob as quais é estudado. Mais pesquisas seriam necessárias para elucidar seu potencial completo e aplicações em várias áreas.

Fórmula: C₃₂H₅₀N₄O₈

Sinónimos:

• Proteasome Inhibitor I
• N-[(Phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-tert-butylester-N-[(1S)-1-formyl-3-methylbutyl]-L-alaninamide
• PROTEASOME INHIBITOR I USP/EP/BP
• N-CBZ-ILE-GLU(O-T-BUTYL)-ALA-LEUCINAL
• Z-IE(OTBU)AL-CHO
• arbobenzoxy-l-isoleucyl-gamma-t-butyl-l-glutamyl-l-alanyl-l-leucinal
• M.W. 618.77 C32H50N4O8
• Z-ILE-GLU(OBUT)-ALA-LEU-H
• PSI PROTEASOME INHIBITOR I
• CBZ-Ile-Glu(OtBu)-Ala-Leu-aldehyde
• ProteasoMe Inhibitor 1
• Z-ILE-GLU(OTBU)-ALA-LEU-ALDEHYDE
• Z-ILE-GLU(OTBU)-ALA-LEU-CHO
• PROTEASOME INHIBITOR I (ALDEHYDE)
• CS-1340
• Cbz-Ile-Glu(OtBu)-Ala-Leu-al
• z-ile-glu(o-t-butyl)-ala-leucinal
• PROTEASOME INHIBITOR PSI
• Z-ILE-GLU(OBUT)-ALA-LEU-H (ALDEHYDE)
• PROTEASOME INHIBITOR I ;Z-ILE-GLU(OTBU)-ALA-LEU-CHO
• BENZYLOXYCARBONYL-L-ISOLEUCYL-[(2S)-2-AMINO-4-(T-BUTYLOXYCARBONYL)BUTANOYL]-L-ALANYL-L-LEUCINAL
• L-AlaninaMide, N-[(phenylMethoxy)carbonyl]-L-isoleucyl-L-a-glutaMyl-N-[(1S)-1-forMyl-3 -Methylbutyl]-, 1,1-diMethylethyl ester
• PSI
• CARBOBENZOXY-L-ISOLEUCYL-GAMMA-T-BUTYL-L-GLUTAMYL-L-ALANYL-L-LEUCINAL
• L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-N-[(1S)-1-formyl-3-methylbutyl]-, 1,1-dimethylethyl ester
• N-Cb
• N-carbobenzyloxy-Ile-Glu(O-tert-butyl)-Ala-leucinal

Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde

CAS: 158442-41-2

Z-IE(OtBu)AL-CHO is an inhibitor of chymotrypsin-like activity of the multicatalytic proteinase complex (MPC; 20S proteasome) in HT4 cells. It is the first inhibitor reported so far which can cause accumulation of ubiquitinylated proteins in neuronal cells. Furthermore, this compound induced massive apoptosis in murine leukaemia L1210 cells. Therefore, proteasome inhibitors may be considered as potential anti-neoplastic agents.

Fórmula: C₃₂H₅₀N₄O₈

Pureza: ≥ 95%

Cor e Forma: White

Peso molecular: 618.77

Ref: 01-4026408

L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-N-[(1S)-1-formyl-3-methylbutyl]-, 1,1-dimethylethyl ester

CAS: 158442-41-2

Fórmula: C₃₂H₅₀N₄O₈

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 618.7614

Ref: IN-DA001Q6O

Z-Ile-Glu(O-t-butyl)-Ala-Leucinal

CAS: 158442-41-2

Fórmula: C₃₂H₅₀N₄O₈

Pureza: ≥ 90.0%

Cor e Forma: White solid

Peso molecular: 618.76

Ref: 7W-GK8272

Abz-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Dap(Dnp)-NH2

CAS: 158442-41-2

Abz-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Dap(Dnp)-NH2 is a synthetic peptide that binds to the toll receptor. The binding of this peptide leads to the signal pathways, which are responsible for the body formation. Abz-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser Arg Dap (Dnp) -NH2 has been shown to have an antiinflammatory effect in rats. This peptide also has a dna binding activity and can be used as a marker for granule neurons in the brain.

Fórmula: C₅₉H₉₃N₂₃O₂₀

Pureza: Min. 95%

Peso molecular: 1,444.54 g/mol

Ref: 3D-SDP-3818-PI

Z-Ile-Glu(OtBu)-Ala-Leu-H (aldehyde)

CAS: 158442-41-2

inhibitor of chymotrypsin-like activity of the multicatalytic proteinase complex in HT4 cells.  Causes accumulation of ubiquitinylated proteins in neuronal cells.

Fórmula: C₃₂H₅₀N₄O₈

Pureza: Min. 95%

Peso molecular: 618.76 g/mol

Ref: 3D-IAT-3169-V

Z-Ile-Glu(OtBu)-Ala-Leu-H (aldehyde)

CAS: 158442-41-2

Please enquire for more information about Z-Ile-Glu(OtBu)-Ala-Leu-H (aldehyde) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Fórmula: C₃₂H₅₀N₄O₈

Peso molecular: 618.76 g/mol

Ref: 3D-IAT-3169

PSI

CAS: 158442-41-2

PSI is a proteasome inhibitor.

Fórmula: C₃₂H₅₀N₄O₈

Pureza: 97% - 98.33%

Cor e Forma: Solid

Peso molecular: 618.76

Ref: TM-T21510

Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde

CAS: 158442-41-2

Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde, also known as ZILEAL, is a potent immunosuppressant that binds to the Toll-like receptor (TLR) and inhibits NF-κB binding activity. It has been shown to reduce the activation of macrophages by inhibiting the production of proinflammatory cytokines such as tumor necrosis factor alpha (TNFα), IL-1β, and IL-6. This drug has been shown to inhibit HIV replication in vitro and was also found to have an antiviral effect against herpes simplex virus type 1 in vivo. ZILEAL also inhibits dsDNA binding activity, which may have potential applications in cancer treatment.

Fórmula: C₃₂H₅₀N₄O₈

Pureza: Min. 95%

Peso molecular: 618.76 g/mol

Ref: 3D-FI111570