CAS 15876-67-2

brometo de distigmina

Descrição:

brometo de distigmina é um composto de amônio quaternário sintético usado principalmente como medicamento para tratar a miastenia gravis, um distúrbio neuromuscular caracterizado por fraqueza nos músculos esqueléticos. Funciona como um inibidor da acetilcolinesterase, melhorando a ação da acetilcolina nas junções neuromusculares, melhorando assim a contração e a força muscular. A substância aparece como um pó cristalino branco a off-white e é solúvel em água, o que facilita sua administração. Sua estrutura química inclui dois grupos de amônio quaternário, contribuindo para sua atividade farmacológica. brometo de distigmina é tipicamente administrado por via oral ou por injeção, e seus efeitos podem ser observados relativamente rápido, tornando-o eficaz para o manejo dos sintomas de fraqueza muscular. No entanto, também pode causar efeitos colaterais, como distúrbios gastrointestinais, aumento da salivação e cãibras musculares. Assim como qualquer medicamento, a dosagem cuidadosa e o monitoramento são essenciais para minimizar os efeitos adversos e garantir a eficácia terapêutica.

Fórmula: C₂₂H₃₂N₄O₄·2Br

InChI: InChI=1/C22H32N4O4.2BrH/c1-23-13-9-11-19(17-23)29-21(27)25(3)15-7-5-6-8-16-26(4)22(28)30-20-12-10-14-24(2)18-20;;/h9-14,17-18H,5-8,15-16H2,1-4H3;2*1H/q+2;;/p-2

Chave InChI: InChIKey=GJHSNEVFXQVOHR-UHFFFAOYSA-L

SMILES: O(C(N(CCCCCCN(C(OC1=C[N+](C)=CC=C1)=O)C)C)=O)C2=C[N+](C)=CC=C2.[Br-]

Sinónimos:

• 3,3'-{Hexane-1,6-Diylbis[(Methylcarbamoyl)Oxy]}Bis(1-Methylpyridinium) Dibromide
• 3-Hydroxy-1-methylpyridinium bromide, hexamethylenebis[methylcarbamate]
• Bc 51
• Distigmine Br
• Distigmine dibromide
• Hexamarium
• Hexamarium bromide
• N,N′-Hexamethylenebis(3-N-methylcarbamoxy-1-methylpyridine)dibromide
• Pyridinium, 3,3′-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-, bromide (1:2)
• Pyridinium, 3,3′-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-, dibromide
• Pyridinium, 3-hydroxy-1-methyl-, bromide, hexamethylenebis[methylcarbamate] (2:1)
• Ubretid
• Ubritil
• BC51
• (1-methylpyridin-1-ium-3-yl) N-methyl-N-[6-[methyl-(1-methylpyridin-1-ium-3-yl)oxycarbonylamino]hexyl]carbamate dibromide
• 3-Hydroxy-1-methylpyridinium
• (1-methylpyridin-1-ium-3-yl) N-methyl-N-[6-[methyl-(1-methylpyridin-1-ium-3-yl)oxycarbonyl-amino]hexyl]carbamate dibromide
• distigmine bromide
• N-methyl-N-[6-[methyl-(1-methylpyridin-1-ium-3-yl)oxycarbonyl-amino]hexyl]carbamic acid (1-methylpyridin-1-ium-3-yl) ester dibromide
• 3,3'-(((Hexane-1,6-diylbis(methylazanediyl))bis(carbonyl))bis(oxy))bis(1-methylpyridin-1-ium) bromide
• Denispan
• Ubtec
• Distigmine

Distigmine Bromide

CAS: 15876-67-2

Cor e Forma: Neat

Ref: 61-FOR1167.00

Pyridinium, 3,3'-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-, bromide (1:2)

CAS: 15876-67-2

Fórmula: C₂₂H₃₂Br₂N₄O₄

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 576.3219

Ref: IN-DA001QU9

Distigmine Bromide

CAS: 15876-67-2

Fórmula: C₂₂H₃₂N₄O₄·2Br

Cor e Forma: White To Off-White Solid

Peso molecular: 416.52 2x79.90

Ref: 4Z-D-137001

Distigmine Bromide-d6

Produto Controlado

CAS: 15876-67-2

Applications Distigmine Bromide-d6 is the isotope labelled analog of Distigmine Bromide (D493530); a cholinesterase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sugaya, K.,e t. al.: Int. J. Urology, 19, 480 (2012)

Fórmula: C₂₂H₂₆D₆N₄O₄•2(Br)

Cor e Forma: Neat

Peso molecular: 582.36

Ref: TR-D493532

Distigmine Bromide

Produto Controlado

CAS: 15876-67-2

Stability Hygroscopic, Temperature Sensitive
Applications Distigmine Bromide is a cholinesterase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sugaya, K.,e t. al.: Int. J. Urology, 19, 480 (2012)

Fórmula: C₂₂H₃₂N₄O₄·2Br

Cor e Forma: Neat

Peso molecular: 576.32

Ref: TR-D493530

Distigmine bromide

CAS: 15876-67-2

Distigmine bromide is a cholinergic agent that can be used to treat the symptoms of urinary incontinence. It is also used to treat underactive bladders and the symptoms associated with it. Distigmine bromide belongs to pharmacological agents and is an acetylcholinesterase inhibitor. This drug is administered by mouth, and its effects are long-lasting. It can be used for the treatment of psychotic disorders as well as for diagnosis of bladder disease.

Fórmula: C₂₂H₃₂N₄O₄•(Br)₂

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 576.32 g/mol

Ref: 3D-FD42999

Distigmine Bromide

CAS: 15876-67-2

Distigmine Bromide is an acetylcholinesterase inhibitor. It is used for the treatment of underactive neurogenic bladder and myasthenia gravis.

Fórmula: C₂₂H₃₂BrN₄O₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 496.42

Ref: TM-T7825