CAS 161796-78-7

Esomeprazol sódico

Descrição:

Esomeprazol sódico é um inibidor da bomba de prótons (IBP) utilizado principalmente para tratar a doença do refluxo gastroesofágico (DRGE) e outras condições associadas à produção excessiva de ácido estomacal. É o S-enantiômero do omeprazol, que melhora sua eficácia e biodisponibilidade. Este composto é tipicamente apresentado como um sal de sódio, o que melhora sua solubilidade em soluções aquosas. Esomeprazol sódico atua inibindo irreversivelmente a enzima H+/K+ ATPase nas células parietais gástricas, levando a uma redução significativa na secreção de ácido gástrico. É caracterizado por sua forma de pó cristalino branco a off-white, com uma fórmula molecular que inclui carbono, hidrogênio, nitrogênio, oxigênio e sódio. A substância é geralmente estável em condições normais, mas deve ser armazenada longe da umidade e da luz para manter sua potência. Comumente administrado por via oral, Esomeprazol sódico é bem absorvido no trato gastrointestinal, com concentrações plasmáticas máximas ocorrendo dentro de algumas horas após a administração. Sua farmacocinética pode ser influenciada por fatores como a ingestão de alimentos e variações metabólicas individuais.

Fórmula: C₁₇H₁₉N₃O₃S·Na

InChI: InChI=1S/C17H19N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8H,9H2,1-4H3,(H,19,20);/t24-;/m0./s1

Chave InChI: InChIKey=HVAJOLFRLWQQQL-JIDHJSLPSA-N

SMILES: S(CC1=C(C)C(OC)=C(C)C=N1)(=O)C=2NC=3C(N2)=CC=C(OC)C3.[Na]

Sinónimos:

• (S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt
• (S)-Omeprazole sodium
• 1H-Benzimidazole, 5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt
• 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt, (S)-
• 1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)
• 1H-benzimidazole, 5-Methoxy-2-[[(4-Methoxy-3,5-dimethyl-2-PYRIDINYL)methyl]sulfinyl]-, sodium salt
• 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt
• Bis[5-Methoxy-2-[(4-Methoxy-3,5-Dimethyl-2-Pyridyl)Methylsulfinyl]Benzimidazol-1-Yl]Magnesium
• Esomeprazole Na
• Esomeprazole sodium salt
• Esomeprazoleandsalts
• H 199/18 sodium
• Sodium 5-Methoxy-2-{[(4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl]Sulfinyl}Benzimidazol-1-Ide
• sodium 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-2,3-dihydrobenzimidazol-1-ide

Esomeprazole Sodium

CAS: 161796-78-7

Cor e Forma: Neat

Ref: 61-FOR3373.00

ESOMEPRAZOLE SODIUM CRS

CAS: 161796-78-7

ESOMEPRAZOLE SODIUM CRS

Cor e Forma: Added Added

Ref: 41-Y0002075

Esomeprazole Sodium

CAS: 161796-78-7

Compounds containing an unfused pyridine ring in the structure, nesoi

Fórmula: C₁₇H₁₈N₃NaO₃S

Cor e Forma: White Off-White Powder

Peso molecular: 367.09666

Ref: 45-1249790

1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)

CAS: 161796-78-7

Fórmula: C₁₇H₁₈N₃NaO₃S

Pureza: %

Cor e Forma: Solid

Peso molecular: 367.3979

Ref: IN-DA001VVZ

Esomeprazole Sodium

CAS: 161796-78-7

Esomeprazole Sodium

Pureza: ≥98%

Peso molecular: 367.4g/mol

Ref: 54-BUP10558

Esomeprazole sodium salt hydrate

CAS: 161796-78-7

Fórmula: C₁₇H₁₈N₃NaO₃S

Pureza: (Titration) ≥ 98.0%

Cor e Forma: White to off-white or pale yellow crystalline powder

Peso molecular: 367.40

Ref: 7W-GP5980

Esomeprazole Sodium Salt

CAS: 161796-78-7

Fórmula: C₁₇H₁₈N₃O₃S·Na

Cor e Forma: White To Off-White Solid

Peso molecular: 344.42 22.99

Ref: 4Z-O-029

Esomeprazole Sodium

CAS: 161796-78-7

Fórmula: C₁₇H₁₈N₃O₃S·Na

Cor e Forma: Neat

Peso molecular: 367.40

Ref: 86-MM3373.00

(S)-Omeprazole Sodium Salt

CAS: 161796-78-7

Fórmula: C₁₇H₁₈N₃NaO₃S

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 367.40

Ref: 3B-O0560

Esomeprazole Sodium

CAS: 161796-78-7

Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.

Fórmula: C₁₇H₁₈N₃O₃S·Na

Pureza: 98.17% - >99.99%

Cor e Forma: Solid

Peso molecular: 367.4

Ref: TM-T2686L

Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide

CAS: 161796-78-7

Pureza: 95.0%

Peso molecular: 367.3999938964844

Ref: 10-F219014

Esomeprazole sodium

CAS: 161796-78-7

Esomeprazole is a proton pump inhibitor used to treat gastroesophageal reflux disease and other conditions where there is too much stomach acid. It is available as a capsule or tablet in doses of 20, 40, and 60 mg. Esomeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium adenosine triphosphate (H+/K+ ATPase) enzyme system at the secretory surface of the gastric parietal cells. Omeprazole is an acidic drug that blocks the H+/K+ ATPase enzyme system. The two drugs have been compared in two-way crossover studies using healthy volunteers who were given omeprazole magnesium for one week followed by esomeprazole sodium for another week. There was no difference in their effect on acid secretion or on heartburn relief. The plasma concentrations of both drugs increased with increasing dose, but there was no significant difference between them in terms of either

Fórmula: C₁₇H₁₈N₃NaO₃S

Pureza: (%) Min. 95%

Cor e Forma: Powder

Peso molecular: 367.4 g/mol

Ref: 3D-IM58097

Esomeprazole sodium - EP

CAS: 161796-78-7

Esomeprazole sodium is a proton pump inhibitor that decreases the production of stomach acid. It is used in the treatment of symptoms such as heartburn, regurgitation, and ulcers caused by gastroesophageal reflux disease (GERD). Esomeprazole sodium has been shown to reduce the amount of acid produced in the stomach and to increase the pH level in the stomach. This drug also has significant interactions with other drugs, which can lead to an increased risk of adverse events. Esomeprazole sodium is excreted from the body through urine and feces. The active form of esomeprazole is also found in wastewater treatment plants and can contribute to antimicrobial resistance.

Fórmula: C₁₇H₁₈N₃NaO₃S

Pureza: Min. 95%

Cor e Forma: White/Off-White Solid

Peso molecular: 367.4 g/mol

Ref: 3D-IE177087

Esomeprazole Sodium

CAS: 161796-78-7

Fórmula: C₁₇H₁₉N₃O₃SNa

Peso molecular: 345.4 : 23.0

Ref: ST-EA-CP-E14021