CAS 161973-10-0

esomeprazol magnésico

Descrição:

esomeprazol magnésico é um inibidor da bomba de prótons (IBP) utilizado principalmente para tratar a doença do refluxo gastroesofágico (DRGE) e outras condições associadas à produção excessiva de ácido estomacal. É o sal de magnésio do esomeprazol, que é o S-enantiômero do omeprazol. Este composto atua inibindo irreversivelmente a enzima H+/K+ ATPase nas células parietais gástricas, levando a uma diminuição na secreção de ácido gástrico. esomeprazol magnésico é tipicamente administrado por via oral e é conhecido por sua melhor biodisponibilidade em comparação com seu contraparte racêmica. A substância é caracterizada por sua aparência de pó cristalino branco a off-white, e é solúvel em água e metanol, tornando-a adequada para várias formulações farmacêuticas. Sua farmacocinética envolve rápida absorção, com concentrações plasmáticas máximas ocorrendo dentro de algumas horas após a administração. Efeitos colaterais comuns podem incluir dor de cabeça, náuseas e dor abdominal, enquanto o uso a longo prazo tem sido associado a riscos potenciais, como deficiência de vitamina B12 e maior suscetibilidade a infecções gastrointestinais.

Fórmula: (C₁₇H₁₈N₃O₃S)₂·Mg

InChI: InChI=1/2C17H18N3O3S.Mg/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h2*5-8H,9H2,1-4H3;/q2*-1;+2/t2*24-;/m00./s1

Chave InChI: InChIKey=KWORUUGOSLYAGD-UHFFFAOYSA-N

SMILES: C(S1=O[Mg+2]2([N]3=C(S(CC4=C(C)C(OC)=C(C)C=N4)=O2)[N-]C=5C3=CC=C(OC)C5)[N]6=C1[N-]C=7C6=CC=C(OC)C7)C8=C(C)C(OC)=C(C)C=N8

Sinónimos:

• (-)-Omeprazole magnesium
• (S)-Omeprazole magnesium
• (T-4)-Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN³]magnesium
• H 199/18
• Magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
• Magnesium Bis(5-Methoxy-2-{[(4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl]Sulfinyl}Benzimidazol-1-Ide)
• Magnesium, bis[5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]-, [T-4-(S),(S)]-
• Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN³]-, (T-4)-
• Nexium
• Perprazole
• Raciper
• magnesium bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide)
• Esomeprazole magnesium
• (T-4)-Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]magnesium
• Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-, (T-4)-
• Esomeprazole magnesium Q: What is the CAS Number of
• Esomeprazole Magnesium(Random Configuration)
• Esomeprazole magnesium Esomeprazole magnesium(API)
• 5-Methoxy-2-((S)-((4-Methoxy-3,5-diMethyl-2-pyridyl)Methyl)sulfinyl-1H-benziMidazole MagnesiuM salt
• ESOMEPRAZOLE MAGNESIUM/SODIUM
• Esomeprazole magnesiumQ: What is
• (S)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole, magnesium salt (2:1)
• Esomeprazole magnesium Q: What is the storage condition of
• Magnesium Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]benzimidazol-1-ide]
• Esomeprazole magnesium Q: What are the applications of
• Esomeprazole magnesium USP/EP/BP
• Chebi:50309
• Esomeprazole magnesium (S-Omeprazole magnesium)
• NEXIUM(esomeprazolemagnesium)
• Bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide) magnesium
• Esomeprazole magnesium API
• Esomeprazole magnesium 5-Methoxy-2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinylmethyl)sulfinyl]-1H-benzimidazole magnesium salt
• ESOMEPRAZOLE MAGNESIUM SAMPLE
• EsMeprazole Magne-siuM Trihydrate
• S-Form magnesium salt

Esomeprazole Magnesium(Random Configuration)

CAS: 161973-10-0

Fórmula: C₃₄H₃₆MgN₆O₆S₂

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 713.1212

Ref: IN-DA001SKP

Esomeprazole Magnesium Salt

CAS: 161973-10-0

Fórmula: C₁₇H₁₈N₃O₃S·Mg

Cor e Forma: White To Off-White Solid

Peso molecular: 2*344.41 24.30

Ref: 4Z-O-0213

Esomeprazole Magnesium

CAS: 161973-10-0

Esomeprazole Magnesium

Pureza: ≥98%

Peso molecular: 713.12g/mol

Ref: 54-BUP13843

Esomeprazole Magnesium(Random Configuration)

CAS: 161973-10-0

Esomeprazole Magnesium(Random Configuration)

Pureza: 99%

Peso molecular: 713.12g/mol

Ref: 54-IN11944

Esomeprazole Magnesium

CAS: 161973-10-0

Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.

Fórmula: C₃₄H₃₆MgN₆O₆S₂

Pureza: 98.76% - 99.73%

Cor e Forma: Solid

Peso molecular: 713.12

Ref: TM-T2686

Esomeprazole magnesium

CAS: 161973-10-0

Esomeprazole magnesium is a proton-pump inhibitor that is used to treat gastroesophageal reflux disease, Zollinger–Ellison syndrome, and other conditions. Esomeprazole magnesium binds to the H+/K+ ATPase enzyme in the stomach and inhibits acid production. It also decreases the release of histamine from cells in the stomach lining, thereby decreasing gastric acid secretion. This drug has been shown to be effective for treating Helicobacter pylori infections and reducing the risk of ulcers associated with nonsteroidal anti-inflammatory drugs in patients with hepatic impairment or those taking omeprazole. The efficacy of esomeprazole magnesium can be measured by its concentration-time curve, which can be determined through blood sampling.

Fórmula: (C₁₇H₁₈N₃O₃S)₂•Mg

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 713.12 g/mol

Ref: 3D-FE46488

Esomeprazole Magnesium

CAS: 161973-10-0

Fórmula: C₃₄H₃₆MgN₆O₆S₂

Peso molecular: 713.12

Ref: ST-EA-CP-E14022