CAS 1620107-33-6

LU 005i

CAS: 1620107-33-6

Potent inhibitor of β5i subunit of immunoproteasomes (IC50 = 6.6 nM), selective over β5c subunit (IC50 = 287 nM). The β5i subunit of immunoproteasomes (iCPs) is the chymotrypsin-like active sites that have implications on anti-cancer affects. On the other hand, β5c subunits are found in constitutive proteasomes (cCPs).

Fórmula: C₃₁H₄₆N₄O₇

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 586.72 g/mol

Ref: 3D-BL165195

LU 005i

Produto Controlado

CAS: 1620107-33-6

Fórmula: C₃₁H₄₆N₄O₇

Cor e Forma: Neat

Peso molecular: 586.72

Ref: TR-L215970

LU-005i

CAS: 1620107-33-6

LU-005i is a powerful inhibitor targeting the β5i subunit of immunoproteasomes, displaying a high potency with an IC 50 value of 6.6 nM, and exhibits selectivity by preferring β5i over the β5c subunit, which has an IC 50 value of 287 nM [1].

Fórmula: C₃₁H₄₆N₄O₇

Cor e Forma: Solid

Peso molecular: 586.72

Ref: TM-T84755