
CAS 1620494-31-6
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3 produtos.
Desmethyl-O-Benzyl Apixaban
CAS:Produto Controlado<p>Applications Desmethyl-O-Benzyl Apixaban is a useful intermediate in the preparation of Apixaban (A726700). Apixaben is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. Apixaban Impurity.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011); Bhirud, S. B., et al.:From U.S. Pat. Appl. Publ. (2015), US 20150353543 A1 20151210<br></p>Fórmula:C31H29N5O4Cor e Forma:NeatPeso molecular:535.593


