CAS 1627696-51-8

LY-3177833

CAS: 1627696-51-8

Fórmula: C₁₆H₁₂FN₅O

Pureza: 99.70%

Peso molecular: 309.2978

Ref: IN-DA00AMH1

LY3177833

CAS: 1627696-51-8

LY3177833

Pureza: ≥98%

Peso molecular: 309.3g/mol

Ref: 54-BUP09515

LY3177833

CAS: 1627696-51-8

LY3177833 is an Cdc7 kinase inhibitor (IC50 : 3.3 nM)

Fórmula: C₁₆H₁₂FN₅O

Pureza: 99.87%

Cor e Forma: Solid

Peso molecular: 309.3

Ref: TM-T7810

LY3177833

CAS: 1627696-51-8

LY3177833 is a protein kinase inhibitor that binds to the ATP-binding pocket of the enzyme, inhibiting its function. LY3177833 has been shown to be effective against colon cancer cells and has been used in clinical trials. The drug was well-tolerated by patients and had no significant side effects. The efficacy of LY3177833 was demonstrated in vitro, where it inhibited the growth of colon cancer cells with an IC50 of 3 nM at 24 hours. LY3177833 also showed anti-tumor effects in a mouse xenograft model, blocking tumor growth and reducing the number of metastases. In addition, LY3177833 inhibits cellular senescence by inhibiting production of β-galactosidase enzymes and the expression of cancer-related genes.

Fórmula: C₁₆H₁₂FN₅O

Pureza: Min. 95%

Peso molecular: 309.3 g/mol

Ref: 3D-CQC69651