CAS 1633009-87-6

BI 689648

CAS: 1633009-87-6

BI 689648 is an amide drug that has been shown to be effective in treating hypertension in nonhuman primates. It is structurally similar to angiotensin II and blocks the binding of angiotensin II to its receptor, the mineralocorticoid receptor. This binding prevents the activation of the receptor and therefore reduces blood pressure. BI 689648 has a number of other effects, including inducing vasodilatation and inhibiting salt reabsorption, as well as blocking the production of aldosterone, which can lead to sodium loss. BI 689648 also binds to and inhibits mineralocorticoid receptors in cardiovascular tissue, which may help prevent cardiovascular diseases.

Fórmula: C₁₆H₁₈N₄O₂

Pureza: Min. 95%

Peso molecular: 298.34 g/mol

Ref: 3D-IQC00987

BI 689648

CAS: 1633009-87-6

BI 689648 is a highly selective inhibitor of aldosterone synthase(CYP11B1 and CYP11B2 with IC50s of 310 and 2.1 nM, respectively).

Fórmula: C₁₆H₁₈N₄O₂

Cor e Forma: Solid

Peso molecular: 298.34

Ref: TM-T14664