CAS 1638250-96-0

7H-PURINE-7-ACETAMIDE, 1,2,3,6-TETRAHYDRO-1,3-DIMETHYL-2,6-DIOXO-N-(6-PHENYL-3-PYRIDAZINYL)-

CAS: 1638250-96-0

Fórmula: C₁₉H₁₇N₇O₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 391.3834

Ref: IN-DA001UF2

ETC-159

CAS: 1638250-96-0

ETC-159

Pureza: ≥95%

Peso molecular: 391.38g/mol

Ref: 54-BUP06111

2-(1,3-Dimethyl-2,6-Dioxo-1,2,3,6-Tetrahydro-7H-Purin-7-Yl)-N-(6-Phenylpyridazin-3-Yl)Acetamide

CAS: 1638250-96-0

2-(1,3-Dimethyl-2,6-Dioxo-1,2,3,6-Tetrahydro-7H-Purin-7-Yl)-N-(6-Phenylpyridazin-3-Yl)Acetamide

Pureza: 98%

Peso molecular: 391.38g/mol

Ref: 54-OR1023188

ETC-159

CAS: 1638250-96-0

ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM.

Fórmula: C₁₉H₁₇N₇O₃

Pureza: 96.87% - 99.30%

Cor e Forma: Solid

Peso molecular: 391.38

Ref: TM-T4043

7H-PURINE-7-ACETAMIDE, 1,2,3,6-TETRAHYDRO-1,3-DIMETHYL-2,6-DIOXO-N-(6-PHENYL-3-PYRIDAZINYL)-

CAS: 1638250-96-0

Pureza: 98%

Peso molecular: 391.3909912

Ref: 10-F801801

1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxo-N-(6-phenyl-3-pyridazinyl)-7H-purine-7-acetamide

Produto Controlado

CAS: 1638250-96-0

Applications 1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxo-N-(6-phenyl-3-pyridazinyl)-7H-purine-7-acetamide is a novel potent PORCN inhibitor that blocks the secretion and activity of all Wnts.
References Madan, B., et al.: Oncogene, 35, 2197-2207 (2016);

Fórmula: C₁₉H₁₇N₇O₃

Cor e Forma: Neat

Peso molecular: 391.383

Ref: TR-T293433

ETC-159

Produto Controlado

CAS: 1638250-96-0

ETC-159 is a monoclonal antibody that binds to and inhibits the function of β-catenin. It is an orally administered drug that has been shown to be effective for the treatment of solid tumours, such as colorectal cancer. ETC-159 blocks the cell signaling pathways mediated by β-catenin, which may lead to tumor suppression. This drug also has the ability to inhibit TNF-α and suppressor genes in cancer cells, which are involved in tumor growth. The chemical structure of this molecule includes a pan-PI3K inhibitor with a potential application in inhibiting cancers that are not responsive to conventional therapy.

Fórmula: C₁₉H₁₇N₇O₃

Pureza: Min. 95%

Peso molecular: 391.38 g/mol

Ref: 3D-NQC25096