CAS 16391-75-6

29-Nordammara-17(20),24-dieno-21-ácido oico, 16-(acetiloxi)-3,11-diidroxi-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-, comp. com 2,2′-iminobis[etanol] (1:1)

Descrição:

29-Nordammara-17(20),24-dien-21-ácido oico, 16-(acetyloxy)-3,11-dihidroxi-, é um composto orgânico complexo caracterizado por sua estrutura esteroidal única, que inclui múltiplos grupos hidroxila e um grupo funcional acetyloxy. Este composto apresenta uma estereoequilibrio específico, denotado por sua configuração detalhada, que influencia sua atividade biológica e interações. A presença de 2,2′-iminobis[etanol] indica que forma um complexo 1:1 com esta amina, potencialmente afetando sua solubilidade e reatividade. O composto provavelmente exibirá várias propriedades farmacológicas, dadas suas características estruturais, que podem incluir efeitos anti-inflamatórios ou outros efeitos terapêuticos. Seu número CAS, 16391-75-6, permite uma identificação precisa em bancos de dados químicos. No geral, as características desta substância sugerem que pode ter aplicações em química medicinal ou farmacologia, embora atividades biológicas específicas exijam investigação adicional por meio de estudos empíricos.

Fórmula: C₃₁H₄₈O₆·C₄H₁₁NO₂

InChI: InChI=1S/C31H48O6.C4H11NO2/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32;6-3-1-5-2-4-7/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36);5-7H,1-4H2/b26-20-;/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-;/m0./s1

Chave InChI: InChIKey=OQZZCXRLEFBPLZ-JCJNLNMISA-N

SMILES: C[C@@]12[C@]3(C)[C@](/C(=C(\CCC=C(C)C)/C(O)=O)/[C@@H](OC(C)=O)C3)(C[C@@H](O)[C@]1([C@]4(C)[C@@](CC2)([C@H](C)[C@H](O)CC4)[H])[H])[H].N(CCO)CCO

Sinónimos:

• (2Z)-2-[(3alpha,4alpha,5alpha,8alpha,9xi,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid - 2,2'-iminodiethanol (1:1)
• (3alpha,8alpha,9beta,13alpha,14beta,16beta,17(Z))-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid, compd. with 2,2'-iminobis(ethanol) (1:1)
• (4alpha,8alpha,9beta,13alpha,14beta,17Z)-16beta-Acetoxy-3alpha,11alpha-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid, compound with 2,2'-iminodiethanol (1:1)
• 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,11α,16β-trihydroxy-, 16-acetate, compd. with 2,2′-iminodiethanol (1:1), (Z)-
• 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-, compd. with 2,2′-iminobis[ethanol] (1:1)
• Diethanolamine fusidate
• Ethanol, 2,2′-iminobis-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oate (salt)

Diethanolamine fusidate

CAS: 16391-75-6

Diethanolamine fusidate

Fórmula: C₃₁H₄₇NaO₆ / C₃₁H₄₈O₆

Pureza: 81.2% / 77.8%

Cor e Forma: White

Peso molecular: 538.32703 / 516.34509

Ref: 47-118

Diethanolamine Fusidate

CAS: 16391-75-6

Fórmula: C₃₅H₅₉NO₈

Cor e Forma: Solid

Peso molecular: 621.8449

Ref: IN-DA001UJN

Diethanolamine Fusidate

CAS: 16391-75-6

Fórmula: C₃₁H₄₈O₆·C₄H₁₁NO₂

Cor e Forma: White To Off-White Solid

Peso molecular: 516.72 105.14

Ref: 4Z-F-5418

Diethanolamine Fusidate

CAS: 16391-75-6

Cor e Forma: Neat

Ref: 86-MM3832.00

Diethanolamine Fusidate

CAS: 16391-75-6

Stability Hygroscopic
Applications A bacteriostatic antibiotic with similar activity and better absorption after oral administration (in animals) than the sodium salt of Fusidic Acid (F865500). Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
References Findon, G. et al.: Lab. Anim. Sci., 41, 462 (1991); Parsons, R.L. et al.: Curr. Chemother. Proc. Int. Cong. Chemother., 10, 384 (1978);

Fórmula: C₃₁H₄₈O₆·C₄H₁₁NO₂

Cor e Forma: Neat

Peso molecular: 621.84

Ref: TR-D441880

Diethanolamine Fusidate

CAS: 16391-75-6

Diethanolamine Fusidate: orally better-absorbed bacteriostatic antibiotic; inhibits protein synthesis in prokaryotes.

Fórmula: C₃₅H₅₉NO₈

Cor e Forma: Solid

Peso molecular: 621.86

Ref: TM-T70323

Diethanolamine fusidate

CAS: 16391-75-6

Diethanolamine fusidate is an aminoglycoside antibiotic that inhibits protein synthesis in bacteria by binding to the ribosomes. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Diethanolamine fusidate has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. This drug also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

Fórmula: C₃₅H₅₉NO₈

Pureza: 95%Min

Peso molecular: 621.84 g/mol

Ref: 3D-FD173301