CAS 16564-43-5

Glicocenodeoxicolato de sódio

Descrição:

Glicocenodeoxicolato de sódio é um sal biliar derivado da conjugação de glicina e ácido chenodeoxicólico, que é um ácido biliar primário. É caracterizado por sua natureza anfipática, possuindo propriedades tanto hidrofílicas quanto hidrofóbicas, o que lhe permite emulsionar eficazmente as gorduras e facilitar sua digestão e absorção no intestino. Este composto é tipicamente encontrado na bile e desempenha um papel crucial no metabolismo lipídico. Como sal de sódio, é solúvel em água, tornando-o útil em várias aplicações bioquímicas, incluindo como surfactante e em protocolos de lise celular. A substância também é conhecida por seu uso potencial em sistemas de entrega de medicamentos e como componente em formulações para produtos farmacêuticos e cosméticos. Sua estrutura molecular inclui um núcleo esteroide, um grupo carboxila e um moiety de glicina, contribuindo para sua atividade biológica. Os dados de segurança indicam que, embora seja geralmente considerado seguro em concentrações apropriadas, deve-se ter cautela devido às suas potenciais propriedades irritantes.

Fórmula: C₂₆H₄₃NO₅·Na

InChI: InChI=1S/C26H43NO5.Na/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29;/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-;/m1./s1

Chave InChI: InChIKey=JIHVOAVQLCYLKZ-YRJJIGPTSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(NCC(O)=O)=O)C)[H])[H].[Na]

Sinónimos:

• Dshs 00533
• Glycine, N-(3α,7α-dihydroxy-5β-cholan-24-oyl)-, monosodium salt
• Glycine, N-[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl]-, monosodium salt
• Glycine, N-[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl]-, sodium salt (1:1)
• Glycochenodeoxycholic Acid Sodium
• NSC 681056
• Sodium [(3,7-Dihydroxy-24-Oxocholan-24-Yl)Amino]Acetate
• Sodium chenodeoxycholylglycine
• Sodium glycochenodeoxycholate
• Sodium glycochenodesoxycholate
• Sodium glycylchenodeoxycholate
• glycine, N-[(3alpha,5beta,7alpha)-3,7-dihydroxy-24-oxocholan-24-yl]-, monosodium salt

Glycine, N-[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl]-, sodium salt (1:1)

CAS: 16564-43-5

Fórmula: C₂₆H₄₂NNaO₅

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 471.6051

Ref: IN-DA001WA1

Glycochenodeoxycholic Acid Sodium Salt (Sodium Glycochenodeoxycholate)

CAS: 16564-43-5

Fórmula: C₂₆H₄₂NO₅·Na

Cor e Forma: White To Off-White Solid

Peso molecular: 448.63 22.99

Ref: 4Z-C-5721

Glycochenodeoxycholic acid sodium salt

CAS: 16564-43-5

Glycochenodeoxycholic acid sodium salt

Fórmula: C₂₆H₄₂NO₅·Na

Pureza: 95%

Cor e Forma: white solid

Peso molecular: 471.60514g/mol

Ref: 54-OR933168

Glycochenodeoxycholic acid sodium salt

CAS: 16564-43-5

Glycochenodeoxycholic acid sodium salt

Pureza: ≥95%

Peso molecular: 471.61g/mol

Ref: 54-BUP16579

Glycochenodeoxycholic acid sodium salt

CAS: 16564-43-5

Fórmula: C₂₆H₄₂NNaO₅

Pureza: (dried basis) ≥ 97.0%

Cor e Forma: White to off-white powder

Peso molecular: 471.61

Ref: 7W-GK7114

Glycochenodeoxycholic acid sodium salt

CAS: 16564-43-5

GCDCA, a bile acid-glycine salt, is a secondary bile acid from colonic microbes.

Fórmula: C₂₆H₄₂NNaO₅

Pureza: 95.48% - 99.82%

Cor e Forma: Solid

Peso molecular: 471.61

Ref: TM-T5259

Glycochenodeoxycholic Acid Sodium, 95%

Produto Controlado

CAS: 16564-43-5

Stability Hygroscopic
Applications Glycochenodeoxycholic Acid Sodium Salt is a bile salt formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.
References Ollila, F., et al.: Langmuir, 17, 7107 (2001), Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004), Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005),

Fórmula: C₂₆H₄₂NO₅·Na

Pureza: 95%

Cor e Forma: White To Light Brown

Peso molecular: 471.61

Ref: TR-G641255

Glycochenodeoxycholic Acid-d7 Sodium Salt (Major)

Produto Controlado

CAS: 16564-43-5

Stability Very Hygroscopic
Applications Labelled Glycochenodeoxycholic Acid (G641255). A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.
References Ollila, F., et al.: Langmuir, 17, 7107 (2001), Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004), Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005),

Fórmula: C₂₆H₃₅D₇NNaO₅

Cor e Forma: Off-White

Peso molecular: 478.65

Ref: TR-G641257

Glycochenodeoxycholic Acid Sodium Salt (Ultra pure, >97%)

Produto Controlado

CAS: 16564-43-5

Applications Glycochenodeoxycholic Acid Sodium Salt is a bile salt formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.
References Ollila, F., et al.: Langmuir, 17, 7107 (2001); Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004); Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005)

Fórmula: C₂₆H₄₂NO₅·Na

Pureza: >97%

Cor e Forma: White To Light Brown

Peso molecular: 471.61

Ref: TR-G641260

Glycochenodeoxycholic acid, sodium salt

CAS: 16564-43-5

Glycochenodeoxycholic acid is a bile salt used in bacteriological culture media as selective inhibitory agent. Enteric bacteria are resistant to the bactericidal effects of bile salts.

Fórmula: C₂₆H₄₂NNaO₅

Pureza: Min. 90.0 Area-%

Peso molecular: 471.61 g/mol

Ref: 3D-G-5222

Glycochenodeoxycholic acid sodium salt

CAS: 16564-43-5

Glycochenodeoxycholic acid sodium salt is a bile acid derivative, which is an important component of the bile produced in the liver. It originates from the metabolism and conjugation of chenodeoxycholic acid with glycine, a process that occurs in the liver. This compound plays a significant role in the emulsification and solubilization of dietary fats, which facilitates their absorption in the intestines.

Fórmula: C₂₆H₄₂NNaO₅

Pureza: Min. 96 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 471.61 g/mol

Ref: 3D-FG15494

Sodium Glycochenodeoxycholate

CAS: 16564-43-5

Fórmula: C₂₆H₄₂NNaO₅

Pureza: >95.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 471.61

Ref: 3B-O0530

Sodium Glycochenodeoxycholate (SGCDC) extrapure, 97%

CAS: 16564-43-5

Fórmula: C₂₆H₄₂NNaO₅

Pureza: min. 97%

Cor e Forma: White to off-white, Crystalline powder

Peso molecular: 471.61

Ref: SR-97971

epi-Glycochenodeoxycholic Acid Sodium Salt-d7

Produto Controlado

CAS: 16564-43-5

Applications epi-Glycochenodeoxycholic Acid Sodium Salt-d7 is a labelled epimer analogue of Glycochenodeoxycholic Acid Sodium Salt (G641255), which is a bile salt formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.
References Ollila, F., et al.: Langmuir, 17, 7107 (2001); Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004); Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005);

Fórmula: C₂₆D₇H₃₅NNaO₅

Cor e Forma: Neat

Peso molecular: 478.648

Ref: TR-G641267