CAS 16808-86-9

6,14-Etenomorfinano-7-metanol, 17-(ciclopropilmetil)-4,5-epoxi-18,19-diidro-3-hidroxi-6-metoxi-α,α-dimetil-, cloridrato (1:1), (5α,7α)-

Descrição:

6,14-Etenomorfinano-7-metanol, 17-(ciclopropilmetil)-4,5-epoxi-18,19-diidro-3-hidroxi-6-metoxi-α,α-dimetil-, cloridrato (1:1), (5α,7α)-, identificado pelo número CAS 16808-86-9, é um composto sintético pertencente à classe dos alcaloides morfinanos. Esta substância exibe uma estrutura molecular complexa caracterizada por múltiplos grupos funcionais, incluindo grupos metanol, epóxido e hidroxilo, que contribuem para suas propriedades farmacológicas. É tipicamente encontrada no contexto de pesquisas relacionadas a analgésicos e potenciais agentes terapêuticos devido à sua interação com os receptores opioides. A presença do grupo ciclopropilmetilo pode influenciar sua afinidade de ligação e seletividade, impactando sua eficácia e perfil de segurança. Como sal de cloridrato, é provável que seja mais solúvel em água, facilitando seu uso em várias formulações. As precauções de segurança e manuseio são essenciais, assim como com muitos compostos desta classe, devido a potenciais efeitos psicoativos e considerações regulatórias.

Fórmula: C₂₆H₃₅NO₄·ClH

InChI: InChI=1S/C26H35NO4.ClH/c1-23(2,29)18-13-24-8-9-26(18,30-3)22-25(24)10-11-27(14-15-4-5-15)19(24)12-16-6-7-17(28)21(31-22)20(16)25;/h6-7,15,18-19,22,28-29H,4-5,8-14H2,1-3H3;1H/t18-,19-,22-,24-,25+,26-;/m1./s1

Chave InChI: InChIKey=UNPUINKKJUSSDZ-UVGWPQHUSA-N

SMILES: O(C)[C@@]12[C@]3([C@]45[C@@]([C@](N(CC6CC6)CC4)(CC7=C5C(O3)=C(O)C=C7)[H])(C[C@@H]1[C@@](C)(C)O)CC2)[H].Cl

Sinónimos:

• (5alpha,7alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha,alpha-dimethyl-6,14-ethenomorphinan-7-methanol hydrochloride
• 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-, hydrochloride (1:1), (5α,7α)-
• 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-, hydrochloride, (5α,7α)-
• 6,14-Ethenomorphinan-7-methanol, 18,19-dihydro-17-(cyclopropylmethyl)-alpha,alpha-dimethyl-4,5-epoxy-3-hydroxy-6-methoxy-, hydrochloride, (5-alpha,7-alpha)-
• 6,14-endo-Ethanetetrahydrooripavine, 21-cyclopropyl-7-alpha-(1-hydroxy-1-methylethyl)-, HCl
• 6,14-endo-Ethanotetrahydrooripavine, 21-cyclopropyl-7α-(1-hydroxy-1-methylethyl)-, hydrochloride
• Diprenorphine hydrochloride
• Revivon

Diprenorphine Hydrochloride (1 mg/ml in Methanol)

Produto Controlado

CAS: 16808-86-9

Fórmula: C₂₆H₃₅NO₄·ClH

Cor e Forma: Single Solution

Peso molecular: 462.02

Ref: TR-KIT4458

Diprenorphine-d3 Hydrochloride

Produto Controlado

CAS: 16808-86-9

Applications Labelled Diprenorphine (D492100). Diprenorphine is a narcotic antagonist. Diprenorphine is closely related to Cyprenorphine.
References Blane, G.F., et al.: J. Pharm. Pharmacol., 19, 367 (1967), Grange, M., et al.: Rev. Med. Vet., 124, 899 (1973), Pert, C.B., et al.: Life Sci., 16, 1849 (1975), Duggett, N.S., et al.: Toxicol. Appl. Pharmacol., 31, 141 (1977),

Fórmula: C₂₆H₃₃D₃ClNO₄

Cor e Forma: Neat

Peso molecular: 465.04

Ref: TR-D492102

Diprenorphine Hydrochloride

Produto Controlado

CAS: 16808-86-9

Applications Diprenorphine is a narcotic antagonist. Diprenorphine is closely related to Cyprenorphine.
References Blane, G.F., et al.: J. Pharm. Pharmacol., 19, 367 (1967), Grange, M., et al.: Rev. Med. Vet., 124, 899 (1973), Pert, C.B., et al.: Life Sci., 16, 1849 (1975), Duggett, N.S., et al.: Toxicol. Appl. Pharmacol., 31, 141 (1977),

Fórmula: C₂₆H₃₅NO₄·ClH

Cor e Forma: Neat

Peso molecular: 462.02

Ref: TR-D492100

Diprenorphine hydrochloride

Produto Controlado

CAS: 16808-86-9

Diprenorphine hydrochloride is a drug that belongs to the class of opioids. It is used as an antidote for opioid overdose and has been shown to be effective in reducing the severity of withdrawal symptoms. Diprenorphine hydrochloride has been shown to inhibit P-glycoprotein (P-gp), which is a membrane protein that transports certain substances from the brain back into the blood. This inhibition leads to increased concentrations of dopamine in the brain, which may contribute to its clinical relevance as an anti-psychotic agent. Diprenorphine hydrochloride also has binding affinity for μ-, κ-, δ-, and ν-opioid receptors, which can lead to decreased locomotor activity, antinociceptive effects, and sedation.

Fórmula: C₂₆H₃₆ClNO₄

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 462.02 g/mol

Ref: 3D-FD22520