CAS 168626-94-6
:Cloridrato de conivaptano
Descrição:
Cloridrato de conivaptano é um composto sintético classificado como um antagonista dual dos receptores de vasopressina, direcionando-se especificamente aos receptores V1A e V2. É utilizado principalmente no tratamento de condições associadas à hiponatremia, particularmente em pacientes com insuficiência cardíaca ou síndrome da secreção inapropriada de hormônio antidiurético (SIADH). A substância é tipicamente administrada por via intravenosa e é conhecida por sua capacidade de promover a aquaresis, que é a excreção de água livre sem a perda de eletrólitos. Cloridrato de conivaptano é caracterizado por sua relativamente baixa solubilidade em água, o que pode influenciar sua formulação e métodos de entrega. O composto possui uma estrutura molecular específica que contribui para sua atividade farmacológica, e é metabolizado principalmente no fígado, com uma meia-vida que permite esquemas de dosagem eficazes. Assim como qualquer medicamento, os efeitos colaterais potenciais podem incluir hipotensão, desequilíbrios eletrolíticos e reações no local da infusão, exigindo monitoramento cuidadoso durante o tratamento.
Fórmula:C32H26N4O2·HCl
InChI:InChI=1/C32H26N4O2.ClH/c1-21-33-28-19-20-36(29-14-8-7-13-27(29)30(28)34-21)32(38)23-15-17-24(18-16-23)35-31(37)26-12-6-5-11-25(26)22-9-3-2-4-10-22;/h2-18H,19-20H2,1H3,(H,33,34)(H,35,37);1H
Chave InChI:InChIKey=BTYHAFSDANBVMJ-UHFFFAOYSA-N
SMILES:C(=O)(N1C=2C(C3=C(CC1)N=C(C)N3)=CC=CC2)C4=CC=C(NC(=O)C5=C(C=CC=C5)C6=CC=CC=C6)C=C4.Cl
Sinónimos:- Conivaptan Monohydrochloride
- N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, monohydrochloride
- N-{4-[(2-Methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamidhydrochlorid
- N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide hydrochloride
- N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(3H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide hydrochloride (1:1)
- N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazépin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide chlorhydrate
- Vaprisol
- Ym 087
- [1,1'-biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, monohydrochloride
- [1,1′-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, hydrochloride (1:1)
- Conivaptan hydrochloride
- N-[4-[(4,5-Dihydro-2-MethyliMidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-Biphenyl]-2-carboxaMide Hydrochloride
- N-(4-(2-methyl-3,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide hydrochloride
- Conivaptan hydrochkoride
- Conivaptan Hydrochloride Q: What is the CAS Number of
- Conivaptan HCl
- Conivaptan HydrochlorideQ: What is
- Conivaptan HCI
- N-[4-(2-Methyl-4,5-dihydro-3H-imidazo[4,5-d][1]benzazepine-6-carbonyl)phenyl]-2-phenylbenzamide hydrochloride
- Conivaptan hydrochloride [usan]
- Conivaptan Hydrochloride Q: What is the storage condition of
- Conivaptan Hydrochloride Q: What are the applications of
- N-[4-(2-Methyl-4,5-dihydro-3H-imidazo[4,5-d][1]benzazepine-6-carbonyl)phenyl]-2-phenylbenzamid
- Unii-75L57R6X36
- Conivaptan hydrochloride USP/EP/BP
- N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][benzazepin-6(1H)-yl)carbonyl]phenyl-[1,1'-biphenyl]-2-carboxamide hydrochloride
- Conivaptan hydrochloride, >=99%
- [1,1'-Biphenyl]-2-carboxamide,N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-,hydrochloride
- N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-biphenyl]-2-carboxamide, hydrochloride (1:1)
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9 produtos.
[1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, hydrochloride (1:1)
CAS:Fórmula:C32H27ClN4O2Pureza:98%Cor e Forma:SolidPeso molecular:535.0354Conivaptan HCl
CAS:Fórmula:C32H26N4O2·HClCor e Forma:White To Off-White SolidPeso molecular:498.59 36.46Conivaptan Hydrochloride
CAS:Produto ControladoFórmula:C32H26N4O2·ClHCor e Forma:NeatPeso molecular:535.04Conivaptan hydrochloride
CAS:<p>Conivaptan hydrochloride (Vaprisol) is an orally active vasopressin V2 and V1A receptor antagonist, used in the therapy of hypervolemic hyponatremia and</p>Fórmula:C32H26N4O2·HClPureza:98.33% - 99.86%Cor e Forma:SolidPeso molecular:535.04Conivaptan Hydrochloride
CAS:Produto Controlado<p>Applications Used in treatment of congestive heart failure.<br>References Mao, Z., et al.: Clin. Ther., 31, 1542 (2009), Arai, Y., et al.: J. Pharm. Sci., 109, 53 (2009),<br></p>Fórmula:C32H26N4O2·ClHCor e Forma:NeatPeso molecular:535.04Conivaptan hydrochloride
CAS:Produto Controlado<p>Conivaptan hydrochloride is a selective, orally active vasopressin receptor antagonist that has been shown to be effective in the treatment of congestive heart failure. Conivaptan hydrochloride is used in experimental models to study its efficacy and safety. The long-term efficacy of conivaptan hydrochloride was demonstrated in a chronic oral study with rats. Optimum concentrations for conivaptan hydrochloride are between 0.5 and 2 mg/kg body weight, which should be administered three times daily. In patients with hepatic impairment, the concentration–time curve of conivaptan hydrochloride may be affected so that higher doses are required to achieve the desired effect. This drug also interacts with drugs such as warfarin, beta blockers, or calcium channel blockers. Patients with high body mass index or systolic pressure should not use this medication because it can lead to serious side effects.</p>Fórmula:C32H27ClN4O2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:535.04 g/mol
![[1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)car…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA001Y6H.jpg&w=3840&q=75)
