CAS 168828-82-8

(5R)-3-(3-Flúor-4-(4-morfolinil)fenil)-5-hidroximetil-2-oxazolidinona

Descrição:

A substância química conhecida como (5R)-3-(3-flúor-4-(4-morfolinil)fenil)-5-hidroximetil-2-oxazolidinona, com o número CAS 168828-82-8, é caracterizada por sua estrutura central de oxazolidinona, que é um composto heterocíclico de cinco membros contendo oxigênio e nitrogênio. Este composto apresenta um grupo hidroximetil e um grupo fenílico fluorinado, que contribuem para sua potencial atividade biológica. A presença do anel de morfolina sugere que pode exibir interações específicas com alvos biológicos, possivelmente melhorando suas propriedades farmacológicas. A estereoquímica indicada pela designação (5R) implica que o composto tem uma disposição tridimensional específica, que pode influenciar significativamente sua reatividade e interação com sistemas biológicos. No geral, este composto é de interesse na química medicinal, particularmente no desenvolvimento de antibióticos e outros agentes terapêuticos, devido às suas características estruturais únicas e potencial eficácia contra vários patógenos. Estudos adicionais seriam necessários para elucidar seu perfil biológico completo e aplicações.

Fórmula: C₁₄H₁₇FN₂O₄

InChI: InChI=1/C14H17FN2O4/c15-12-7-10(17-8-11(9-18)21-14(17)19)1-2-13(12)16-3-5-20-6-4-16/h1-2,7,11,18H,3-6,8-9H2/t11-/m1/s1

SMILES: c1cc(c(cc1N1C[C@H](CO)OC1=O)F)N1CCOCC1

Sinónimos:

• Linezolid Intermediate
• (R)-3-(3-Fluoro-4-Morpholinophenyl)-5-(Hydroxymethyl)Oxazolidin-2-One
• R-N-(3-Fluoro-4-Morpholinylphenyl)-2-Oxo-5-Oxazolidinylmethanol
• (5R)-3-[3-Fluoro-4-(4-Morpholinyl)Phenyl]-5-(Hydroxymethyl)-2-Oxazolidinone
• 2-Oxazolidinone, 3-[3-Fluoro-4-(4-Morpholinyl)Phenyl]-5-(Hydroxymethyl)-, (5R)-
• 3-(3-Fluoro-4-(4-Morpholinyl)Phenyl)-5-Hydroxymethyl-(5R)-2-Oxazolidione
• 2-Oxazolidinone,3-[3-Fluoro-4-(4-Morpholinyl)Phen
• R)-5-(Hydroxymethyl)-3-(3-Fluoro-4-Morpholinopheny
• (5R)-3-[3-Fluoro-4-(4-Morpholinyl)Phenyl]-5-(Hydroxymethyl)-2-Oxazolindinone
• (R)-[N-3-(3-Fluoro-4-Morpholinylphenyl)-2-Oxo-5-Oxazolidinyl]Methanol
• (5R)-3-[3-Fluoro-4-(Morpholin-4-Yl)Phenyl]-5-(Hydroxymethyl)-1,3-Oxazolidin-2-One
• (R)-(3-(3-Flouro-4-Morpholinophenyl)-2-Oxo-5-Oxazolidinyl)Methyl
• (R)-N-[[3-(3-Fluoro-4-Morpholinyl)Phenyl]-2-Oxo-5-Oxazolidinyl]Methanol

(5R)-3-(3-Fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one

CAS: 168828-82-8

Fórmula: C₁₄H₁₇FN₂O₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 296.2942

Ref: IN-DA0032F0

Linezolid Impurity 46

CAS: 168828-82-8

Fórmula: C₁₄H₁₇FN₂O₄

Cor e Forma: Off-White Solid

Peso molecular: 296.30

Ref: 4Z-L-077

PNU-100440, 10mM (in DMSO)

CAS: 168828-82-8

PNU-100440, 10mM (in DMSO)

Pureza: ≥98%

Peso molecular: 296.29g/mol

Ref: 54-BUP19965

(5R)-3-(3-Fluoro-4-(4-Morpholinyl)Phenyl)-5-Hydroxymethyl-2-Oxazolidione

CAS: 168828-82-8

(5R)-3-(3-Fluoro-4-(4-Morpholinyl)Phenyl)-5-Hydroxymethyl-2-Oxazolidione

Pureza: 98%

Peso molecular: 296.29g/mol

Ref: 54-PC109255

PNU-100440

CAS: 168828-82-8

PNU-100440

Pureza: ≥98%

Peso molecular: 296.29g/mol

Ref: 54-BUP10634

(5R)-3-(3-Fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one

Produto Controlado

CAS: 168828-82-8

Fórmula: C₁₄H₁₇FN₂O₄

Cor e Forma: Neat

Peso molecular: 296.30

Ref: 86-MM3300.05

PNU-100440

CAS: 168828-82-8

PNU-100440 is a biologically active compound. It is an intermediate in the synthesis of linezolid dimers, an impurity of the antibacterial agent Linezolid.

Fórmula: C₁₄H₁₇FN₂O₄

Pureza: 99.09%

Cor e Forma: Solid

Peso molecular: 296.29

Ref: TM-T19645

[(R)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methanol

Produto Controlado

CAS: 168828-82-8

Applications [(R)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methanol is an intermediate in the synthesis of Linezolid Dimer (L466520), an impurity of the antibacterial agent Linezolid (L466500).
References Xu, Heteroatom, Chem., 19, 316 (2008); Wang, J.W., et al.: Lett. Org. Chem., 5, 336 (2008);

Fórmula: C₁₄H₁₇FN₂O₄

Cor e Forma: Light Red

Peso molecular: 296.30

Ref: TR-F594975

(R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one

CAS: 168828-82-8

(R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one (FPH) is a synthetic drug product that is used as an impurity standard in the synthesis of pharmaceuticals. It is also used in metabolism studies and research and development. FPH has been shown to be a metabolite of the drug product, 3-(3-fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one, which is classified as an API impurity for pharmacopoeia purposes. FPH has a molecular formula of C11H14FO2N2O and a molecular weight of 222.26 g/mol. The CAS number for FPH is 168828-82-8.

Fórmula: C₁₄H₁₇FN₂O₄

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 296.29 g/mol

Ref: 3D-IF58045

(R)-3-(3-Fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one

CAS: 168828-82-8

Fórmula: C₁₄H₁₇FN₂O₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 296.298

Ref: 10-F091470

Linezolid Hydroxymethyl Impurity

CAS: 168828-82-8

Fórmula: C₁₄H₁₇FN₂O₄

Peso molecular: 296.29

Ref: ST-EA-CP-L40006