CAS 16941-32-5

glucagon

Descrição:

glucagon é um hormônio peptídico produzido pelas células alfa do pâncreas, principalmente envolvido no metabolismo da glicose. É composto por 29 aminoácidos e desempenha um papel crucial no aumento dos níveis de glicose no sangue, promovendo a glicogenólise e a gluconeogênese no fígado. glucagon é tipicamente liberado em resposta a baixos níveis de açúcar no sangue, atuando como um hormônio contrarregulador da insulina. Sua estrutura inclui uma cadeia única de aminoácidos com grupos funcionais específicos que facilitam sua atividade biológica. O número CAS 16941-32-5 identifica glucagon em bancos de dados químicos, garantindo uma comunicação precisa sobre essa substância. Em contextos terapêuticos, glucagon é usado como medicamento para tratar hipoglicemia severa e é administrado por injeção. Também é utilizado em procedimentos diagnósticos, como em estudos de imagem do trato gastrointestinal. No geral, glucagon é essencial para manter a homeostase da glicose e é um jogador chave na regulação metabólica.

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

InChI: InChI=1/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1

Sinónimos:

• Glucagon (1-29) (human, bovine, porcine)
• Glucagon, human recombinant
• H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH
• L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine
• Glucagon Hydrochloride(Human)

Glucagon (1-29) (human, rat, porcine)

CAS: 16941-32-5

Glucagon is a 29 amino acid containing peptide hormone processed from proglucagon. As a counterregulatory hormone for insulin, glucagon plays a critical role in maintaining glucose homeostasis in vivo in both animals and humans. Not surprisingly, glucagon and glucagon receptor have been pursued extensively as potential targets for the therapeutic treatment of diabetes. As Aβ peptides and IAPP, glucacon tends to form gel-like fibrillar aggregates. These fibrils were found to be toxic through the activation of apoptotic signaling pathways. Hence the aggregation behavior of glucagon has been studied extensively.

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

Pureza: 100.0%

Cor e Forma: White Powder

Peso molecular: 3482.8

Ref: 01-4033017

Glucagon (1-29) (human, rat, porcine)

CAS: 16941-32-5

Bachem ID: 4088814.

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

Pureza: 96.4%

Cor e Forma: White Lyophilisate

Peso molecular: 3482.8

Ref: 01-4088814

HUMAN GLUCAGON CRS

CAS: 16941-32-5

HUMAN GLUCAGON CRS

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

Peso molecular: 3482.747

Ref: 41-Y0000191

Glucagon

CAS: 16941-32-5

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 3482.7473

Ref: IN-DA0039VM

Glucagon

CAS: 16941-32-5

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

Pureza: (HPLC) ≥ 95.0%

Cor e Forma: White powder

Peso molecular: 3482.75

Ref: 7W-GX2829

Glucagon

CAS: 16941-32-5

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

Peso molecular: 3482.80

Ref: 4Z-PG-194007

Glucagon PentaHCl

CAS: 16941-32-5

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S·5HCl

Peso molecular: 3482.80 5*36.46

Ref: 4Z-PG-194012

Glucagon Hydrochlide

CAS: 16941-32-5

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

Pureza: 95%~99%

Cor e Forma: White to Off-white Powder

Peso molecular: 3482.75

Ref: BP-BPPG036

Glucagon (1-29), bovine, human, porcine

CAS: 16941-32-5

Corynoxine B (Cory B) is a naturally occurring alkaloid isolated from Uncaria rhynchophylla (Miq. ) and is an autophagy inducer.

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

Pureza: 99.56% - 99.56%

Cor e Forma: Solid

Peso molecular: 3482.75

Ref: TM-T15389

Glucagon RS

CAS: 16941-32-5

Cor e Forma: White Solid

Ref: 2K-1048400021

Glucagon tifluoroacetic acid

CAS: 16941-32-5

Please enquire for more information about Glucagon tifluoroacetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S•(CF₃CO₂H)x

Peso molecular: 3,482.75 g/mol

Ref: 3D-G-1000

Glucagon (Human)

CAS: 16941-32-5

Glucagon (Human) is a recombinant peptide hormone, which is synthesized to mimic the natural glucagon produced by alpha cells in the pancreas. This biopharmaceutical is derived from a DNA recombinant technology source, offering a high level of purity and consistency. Its mode of action involves binding to glucagon receptors on liver cells, stimulating glycogenolysis and gluconeogenesis. This results in the rapid conversion of glycogen into glucose, thereby raising blood sugar levels.Glucagon (Human) is primarily utilized in the treatment of severe hypoglycemia, especially in diabetic patients unable to consume oral glucose due to unconsciousness or confusion. Its application is critical in acute settings where rapid intervention is necessary to prevent neurological damage from prolonged hypoglycemia. Additionally, the research and clinical use of glucagon extend to investigating its potential in counteracting beta-blocker and calcium channel blocker overdoses, where it acts to increase cardiac output. This hormone's pharmaceutical development has provided a crucial tool in both emergency response and broader therapeutic research contexts.

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

Pureza: Min. 95%

Peso molecular: 3,482.7 g/mol

Ref: 3D-PGL-4098-S

Glucagon (1-29), bovine, human, porcine

CAS: 16941-32-5

Glucagon (1-29), bovine, human, porcine, is a peptide hormone, which is derived from bovine, human, and porcine sources. It comprises 29 amino acids and functions as a crucial regulator of glucose metabolism by promoting the increase of blood glucose levels. The mode of action involves binding to receptors on liver cells, activating adenylate cyclase, and subsequently increasing intracellular cyclic AMP. This cascade triggers glycogenolysis and gluconeogenesis, leading to elevated blood glucose.In scientific research, Glucagon (1-29), bovine, human, porcine, is utilized to study metabolic pathways and the regulation of glucose homeostasis. Its applications extend to diabetes research, where it serves as a model for understanding glucagon's role in insulin resistance and pancreatic beta-cell dysfunction. Furthermore, this product is employed in the development of therapeutic strategies for hypoglycemic events experienced by diabetic patients. It also serves as a tool in pharmacological studies to elucidate receptor-ligand interactions and signaling mechanisms in different species.

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

Pureza: Min. 95%

Peso molecular: 3,482.78 g/mol

Ref: 3D-PG16975

Glucagon

CAS: 16941-32-5

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

Peso molecular: 3482.8

Ref: ST-EA-CP-G38025

Glucagon (1-29) trifluoroacetate salt, human

CAS: 16941-32-5

A peptide hormone that plays a role in maintaining glucose homeostasis This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Cor e Forma: White, Lyophilized powder

Ref: 02-J60827

Glucagon (HUMAN)

CAS: 16941-32-5

Polypeptide, protein and glycoprotein hormones, their derivatives and structural analogues, nesoi

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

Cor e Forma: White Powder

Peso molecular: 3480.6157

Ref: 45-1294036

Glucagon Hydrochloride

CAS: 16941-32-5

Please enquire for more information about Glucagon Hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Fórmula: C₁₅₃H₂₂₅N₄₃O₄₉S

Peso molecular: 3,482.82 g/mol

Ref: 3D-PP51369