CAS 1698878-14-6

Nampt-IN-1

CAS: 1698878-14-6

Fórmula: C₂₀H₂₅N₃O₅S

Pureza: 99%

Peso molecular: 419.4946

Ref: IN-DA00ABOK

Nampt-IN-1

CAS: 1698878-14-6

Nampt-IN-1

Pureza: ≥95%

Peso molecular: 419.49g/mol

Ref: 54-BUP09433

Nampt-IN-1

CAS: 1698878-14-6

Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.

Fórmula: C₂₀H₂₅N₃O₅S

Pureza: 99.28% - 99.4%

Cor e Forma: Solid

Peso molecular: 419.49

Ref: TM-T4376

LSN 3154567 (Nampt-IN-1)

CAS: 1698878-14-6

Fórmula: C₂₀H₂₅N₃O₅S

Peso molecular: 419.50

Ref: 4Z-L-182001

LSN 3154567

CAS: 1698878-14-6

Nicotinamide phosphoribosyl transferase (NAMPT) competitive inhibitor with IC50 = 3.1 nM. A major consequence of NAMPT inhibition is the attenuation of glycolysis at the GADPH step because this enzyme requires NAD+ for activity. The compound exhibits broad spectrum anti-cancer activity and significant tumor regression was observed in vitro. Although retinal and haematological toxicity has been associated with NAMPT inhibitors, LSN 3154567 does not lead to retinopathy in rats and can be mitigated with co-administration of nicotinic acid.

Fórmula: C₂₀H₂₅N₃O₅S

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 419.5 g/mol

Ref: 3D-BL165041

Nampt-IN-1

Produto Controlado

CAS: 1698878-14-6

Fórmula: C₂₀H₂₅N₃O₅S

Cor e Forma: Neat

Peso molecular: 398.361

Ref: TR-N285780