CAS 17090-79-8

Monensina

Descrição:

Monensina é um antibiótico ionóforo de polietileno produzido principalmente pela fermentação da bactéria *Streptomyces cinnamonensis*. É caracterizado por sua capacidade de transportar íons de sódio através de membranas lipídicas, o que interrompe o equilíbrio iônico celular e afeta vários processos biológicos. Monensina é um pó cristalino branco a off-white que é solúvel em solventes orgânicos como metanol e etanol, mas tem solubilidade limitada em água. Sua fórmula molecular é C36H61NaO11, e possui uma estrutura complexa com múltiplos anéis de éter cíclicos. Monensina é amplamente utilizado na medicina veterinária, particularmente em gado, para melhorar a eficiência alimentar e prevenir a coccidiose, uma doença parasitária. Além disso, tem sido estudado por suas potenciais aplicações na medicina humana, incluindo tratamento de câncer e como agente antiviral. No entanto, seu uso deve ser cuidadosamente gerenciado devido à potencial toxicidade e ao desenvolvimento de resistência em organismos-alvo. No geral, Monensina é um composto significativo tanto em contextos agrícolas quanto farmacêuticos.

Fórmula: C₃₆H₆₁NaO₁₁

InChI: InChI=1/C37H64O10.Na/c1-11-35(32-21(4)18-27(43-32)29-20(3)17-22(5)37(41,12-2)46-29)14-13-28(44-35)34(9)15-16-36(47-34)19-26(38)23(6)31(45-36)24(7)30(42-10)25(8)33(39)40;/h20-32,38,41H,11-19H2,1-10H3,(H,39,40);/q;+1/p-1/t20-,21-,22+,23+,24+,25-,26-,27+,28+,29?,30+,31-,32?,34-,35-,36?,37-;/m0./s1

Chave InChI: InChIKey=GAOZTHIDHYLHMS-KEOBGNEYSA-N

SMILES: C[C@@]1(O[C@]2(O[C@]([C@H]([C@H]([C@@H](C(O)=O)C)OC)C)([C@H](C)[C@@H](O)C2)[H])CC1)[C@@]3(O[C@@](CC)(CC3)[C@@]4(O[C@](C[C@@H]4C)([C@]5(O[C@](CO)(O)[C@H](C)C[C@@H]5C)[H])[H])[H])[H]

Sinónimos:

• 1,6-Dioxaspiro[4.5]decane, monensin deriv.
• 1,6-Dioxaspiro[4.5]decane-7-butyric acid, 2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-
• A 3823A
• Elancoban
• Monelan
• Monensic acid
• Monensin A
• Rumensin 90
• Rumensin CRC
• Stereoisomer of 2-[2-ethyloctahydro-3'-methyl-5'-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butanoic acid
• Monensin
• (2R,3S,4R)-4-[(2R,5R,7S,8R,9S)-2-{(2S,2'S,3'R,5R,5'S)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid
• (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-{(2S,2'R,3'S,5R,5'R)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid
• sodium (2S,3R,4R)-4-[(2S,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(3S,5R)-5-[(3S,5R,6S)-6-ethyl-6-hydroxy-3,5-dimethyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]tetrahydrofuran-2-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-methoxy-2-methyl-pentanoate
• 4-(2-{2-Ethyl-5'-[6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl)-3-methoxy-2-methylpentanoate
• 2-(5-ethyltetrahydro-5-(tetrahydro-3-6-dioxaspiro(4.5)decane-7-butyricacid
• 1,6-dioxaspiro[4.5]decane-7-butanoato, 2-[2-ethyloctahydro-3'-methyl-5'-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl-, ion(1-)
• 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid
• MONENSIN(PURE)
• monensicacid
• Monensine sodium
• MONENSIN SODIUM
• MONENSIN SODIUM SALT
• gamma,2,8-tetramethyl--furyl)-2-furyl)-9-hydroxy-beta-methoxy-alph
• 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy--methoxy-a,,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric Acid
• a3823a
• 4-[3-[5-ETHYL-5-[5-[6-HYDROXY-6-(HYDROXYMETHYL)-3,5-DIMETHYL-TETRAHYDROPYRAN-2-YL]-3-METHYL-TETRAHYDROFURAN-2-YL]-TETRAHYDROFURAN-2-YL]-9-HYDROXY-3,8-DIMETHYL-4,6-DIOXASPIRO[4.5]DEC-7-YL]-3-METHOXY-2-METHYL-PENTANOATE
• MONENSINSODIUMSALT(30%)
• MONENSIN A SODIUM SALT
• MONENSIN NA
• Romensin

Monensin

CAS: 17090-79-8

Fórmula: C₃₆H₆₂O₁₁

Peso molecular: 670.87

Ref: 7W-GP7543

Monensin

CAS: 17090-79-8

Monensin, from Streptomyces cinnamonensis, inhibits Wnt/β-catenin. Potential anticancer agent.

Fórmula: C₃₆H₆₂O₁₁

Pureza: 98%

Cor e Forma: Crystals White Or Off-White Crystals

Peso molecular: 670.87

Ref: TM-T1033L

Monensin

CAS: 17090-79-8

Monensin is a polyether ionophore antibiotic, which is derived from the fermentation of the bacterium *Streptomyces cinnamonensis*. It operates by disrupting ion transport across biological membranes, primarily by facilitating the exchange of sodium and potassium ions. This ionophore action alters the osmotic balance in target cells, leading to their destabilization and death, particularly in Gram-positive bacteria and certain protozoa.

Fórmula: C₃₆H₆₂O₁₁

Pureza: Min. 95%

Peso molecular: 670.87 g/mol

Ref: 3D-FM31903