CAS 171500-79-1

5,31-Dicloro-38-de(metoxicarbonil)-7-desmetil-19-desoxi-56-O-[2-desoxi-2-(10-metilundecanamido)-β-Dglucopiranosil]-38-[N-[3-(dimetilamino)-propil]carbamoil]-42-O-α-D-manopiranosil-N15-metilristomicina A aglicona

Descrição:

5,31-Dicloro-38-de(metoxicarbonila)-7-desmetil-19-desoxi-56-O-[2-desoxi-2-(10-metilundecanamido)-β-D-glucopiranosídeo]-38-[N-[3-(dimetilamino)-propil]carbamoilo]-42-O-α-D-mannopiranosídeo-N15-metilristomicina A aglicona, com número CAS 171500-79-1, é um composto orgânico complexo caracterizado por sua estrutura intrincada, que inclui múltiplos grupos funcionais e substituintes. Esta substância apresenta grupos dicloro e carbamoilo, indicando potencial reatividade e atividade biológica. A presença de unidades de açúcar sugere que pode ter propriedades glicosídicas, o que poderia influenciar sua solubilidade e interação com sistemas biológicos. O composto provavelmente exibirá propriedades antimicrobianas, pois está relacionado à ristomicina, um antibiótico conhecido. Sua complexidade estrutural também pode contribuir para seu perfil farmacológico, incluindo potenciais efeitos nas membranas celulares ou na atividade enzimática. No geral, este composto representa uma área significativa de interesse em química medicinal, particularmente no desenvolvimento de novos agentes terapêuticos.

Fórmula: Unspecified

InChI: InChI=1S/C88H100Cl2N10O28/c1-38(2)13-10-8-6-7-9-11-14-61(106)94-70-73(109)75(111)78(86(120)121)128-87(70)127-77-58-31-43-32-59(77)124-55-24-19-42(29-50(55)89)71(107)69-85(119)98-67(80(114)92-25-12-26-100(4)5)48-33-44(102)34-57(125-88-76(112)74(110)72(108)60(37-101)126-88)62(48)47-28-40(17-22-52(47)103)65(82(116)99-69)95-83(117)66(43)96-84(118)68-49-35-46(36-54(105)63(49)90)123-56-30-41(18-23-53(56)104)64(91-3)81(115)93-51(79(113)97-68)27-39-15-20-45(122-58)21-16-39/h15-24,28-36,38,51,60,64-76,78,87-88,91,101-105,107-112H,6-14,25-27,37H2,1-5H3,(H,92,114)(H,93,115)(H,94,106)(H,95,117)(H,96,118)(H,97,113)(H,98,119)(H,99,116)(H,120,121)/t51-,60-,64-,65-,66-,67+,68+,69+,70-,71-,72-,73-,74+,75+,76+,78+,87-,88+/m1/s1

Chave InChI: InChIKey=KGPGQDLTDHGEGT-SZUNQUCBSA-N

SMILES: O(C1=C2C([C@@H](C(NCCCN(C)C)=O)NC(=O)[C@@]3([C@H](O)C=4C=C(Cl)C(=CC4)OC=5C=C6[C@](C(=O)N[C@](C=7C=C2C(O)=CC7)(C(=O)N3)[H])(NC(=O)[C@@]8(C=9C=C(OC=%10C=C([C@@H](NC)C(=O)N[C@@](C(=O)N8)(CC=%11C=CC(OC(=C6)C5O[C@H]%12[C@H](NC(CCCCCCCCC(C)C)=O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O%12)=CC%11)[H])C=CC%10O)C=C(O)C9Cl)[H])[H])[H])=CC(O)=C1)[C@H]%13O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]%13O

Sinónimos:

• 5,31-Dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-β-<span class="text-smallcaps">D</smallcap>-glucopyranuronosyl]-38-[[[3-(dimethylamino)propyl]amino]carbonyl]-42-O-α-<smallcap>D</span>-mannopyranosyl-N¹⁵-methylristomycin A aglycone
• A-A 1
• B 7011
• Bi-397
• Dalbavancin
• Dalbavancin B₀
• Dalvance
• Mdl 63397
• Ristomycin A aglycone, 5,31-dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-β-<span class="text-smallcaps">D</smallcap>-glucopyranuronosyl]-38-[[[3-(dimethylamino)propyl]amino]carbonyl]-42-O-α-<smallcap>D</span>-mannopyranosyl-N¹⁵-methyl-
• V-Glycopeptide
• Ver 001
• 5,31-Dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-β-D-glucopyranuronosyl]-38-[[[3-(dimethylamino)propyl]amino]carbonyl]-42-O-α-D-mannopyranosyl-N15-methylristomycin A aglycone
• Dalbavancin(BI 397, MDL 63397)

Ristomycin A aglycone,5,31-dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-b-D-glucopyranuronosyl]-38-[[[3-(dimethylamino)propyl]amino]carbonyl]-42-O-a-D-mannopyranosyl-N15-methyl-

CAS: 171500-79-1

Fórmula: C₈₈H₁₀₀Cl₂N₁₀O₂₈

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1816.6918

Ref: IN-DA00ABNL

Dalbavancin

CAS: 171500-79-1

Fórmula: C₈₈H₁₀₀Cl₂N₁₀O₂₈

Peso molecular: 1816.71

Ref: 4Z-D-176013

Dalbavancin

CAS: 171500-79-1

Dalbavancin (BI-397) is a lipoglycopeptide antibiotic effective against Gram-positive pathogens, MRSA, MRSE, with MIC90s of 0.06-0.25 μg/mL.

Fórmula: C₈₈H₁₀₀Cl₂N₁₀O₂₈

Pureza: 99.09%

Cor e Forma: Solid

Peso molecular: 1816.71

Ref: TM-T21358

Dalbavancin Hydrochloride

Produto Controlado

CAS: 171500-79-1

Applications Dalbavancin is a second-generation lipoglycopeptide antibiotic. It is a semisynthetic lipoglycopeptide that was designed to improve upon the natural glycopeptides currently available, vancomycin and teicoplanin.
References Scheinfeld, N.: Derm. Online J., 12 (2006); Chen, A., et al.: Int. J. Clin. Prac., 61, 853 (2007)

Fórmula: C₈₈H₁₀₀Cl₂N₁₀O₂₈·HCl

Cor e Forma: Neat

Peso molecular: 1816.69

Ref: TR-D110000

Dalbavancin

CAS: 171500-79-1

Dalbavancin is a lipoglycopeptide antibiotic with action against gram-positive bacteria, including MRSA and is used for treating acute bacterial skin and skin structure infections.

Fórmula: C₈₈H₁₀₀Cl₂N₁₀O₂₈

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 1,816.69 g/mol

Ref: 3D-AD30090

Dalbavancin

CAS: 171500-79-1

Fórmula: C₈₈H₁₀₀Cl₂N₁₀O₂₈

Peso molecular: 1816.7

Ref: ST-EA-CP-D132000