CAS 17321-77-6
:cloridrato de clomipramina
Descrição:
cloridrato de clomipramina é um antidepressivo tricíclico usado principalmente no tratamento do transtorno obsessivo-compulsivo (TOC) e outros transtornos de humor. Funciona inibindo a recaptação de neurotransmissores, particularmente serotonina e norepinefrina, aumentando assim sua disponibilidade na fenda sináptica. Este composto aparece como um pó cristalino branco a off-white e é solúvel em água, tornando-o adequado para administração oral. cloridrato de clomipramina tem uma meia-vida relativamente longa, o que permite a dosagem uma vez ao dia em muitos casos. Seu perfil farmacológico inclui uma variedade de efeitos colaterais, como sedação, boca seca e potenciais efeitos cardiovasculares, exigindo monitoramento cuidadoso em pacientes. A substância é classificada como um medicamento sob prescrição e está sujeita a controles regulatórios devido ao seu potencial para efeitos colaterais e interações com outros medicamentos. No geral, cloridrato de clomipramina é um agente terapêutico importante na psiquiatria, particularmente para pacientes com TOC resistente ao tratamento.
Fórmula:C19H24Cl2N2
InChI:InChI=1/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H
Chave InChI:InChIKey=WIMWMKZEIBHDTH-UHFFFAOYSA-N
SMILES:C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=C(Cl)C2.Cl
Sinónimos:- 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
- 3-Chloro-5-(3-dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
- 3-Chloroimipramine hydrochloride
- 5H-Dibenz[b,f]azepine, 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
- 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
- 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
- Anafranil
- Anaphranil
- Anatranil
- Chlorimipramine hydrochloride
- Chloroimipram-ine HCl
- Chloroimipramine monohydrochloride
- Clomipramine HCl
- ANAFRANIL HYDROCHLORIDE
- 5H-Dibenzb,fazepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
- CLOMIPRAMINE HYDROCHLORIDE
- Clomipraminhydrochlorid
- 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride
- Chlomipramine
- 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-5h-dibenz[b,f]azepine monohydrochloride
- 3-chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(b,f)azepinemono
- 3-CHLORO-10,11-DIHYDRO-N,N-DIMETHYL-5H-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
- f)azepine,10,11-dihydro-3-chloro-5-(3-(dimethylamino)propyl)-5h-dibenz(mon
- f)azepine-5-propanamine,3-chloro-10,11-dihydro-n,n-dimethyl-5h-dibenz(mo
- CLOMIPRAMINE HYDROCHLORIDE \ SEROTONIN U PTAKE INHIBITOR, ANTIDEPRESSANT
- 3-chloroimipraminehydrochloride
- CHLOROIMIPRAMINE HYDROCHLORIDE
- Ver mais sinónimos
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22 produtos.
Clomipramine hydrochloride
CAS:<p>Potent, selective 5-HT uptake blocker</p>Fórmula:C19H24Cl2N2Cor e Forma:White to pale yellow, Crystals or crystalline powderPeso molecular:351.32Clomipramine hydrochloride
CAS:Clomipramine hydrochlorideFórmula:C19H23ClN2HClPureza:99.6%Cor e Forma:White To Off-WhitePeso molecular:350.13165Clomipramine Hydrochloride
CAS:Antidepressants, tranquilizers and other psychotherapeuFórmula:C19H23ClN2·ClHCor e Forma:White Yellow PowderPeso molecular:350.13165(3-{5-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)dimethylamine hydrochloride
CAS:Fórmula:C19H24Cl2N2Pureza:99%Cor e Forma:SolidPeso molecular:351.3133Clomipramine hydrochloride
CAS:Clomipramine HCl (Anafranil) is a serotonin-inhibiting tricyclic antidepressant, well-absorbed and metabolized to desmethylclomipramine in the liver.Fórmula:C19H23ClN2·HClPureza:99.04% - 99.47%Cor e Forma:White To Slightly Yellow Crystalline PowderPeso molecular:351.31Clomipramine-13C-d3 HCl
CAS:Fórmula:C1813CH20D3ClN2·HClCor e Forma:White To Off-White SolidPeso molecular:318.87 36.46Clomipramine Hydrochloride
CAS:Produto ControladoFórmula:C19H23ClN2·ClHCor e Forma:NeatPeso molecular:351.31Clomipramine Hydrochloride (Standard)
CAS:Clomipramine Hydrochloride (Standard) is the standard substance of Clomipramine Hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.Fórmula:C19H23ClN2·HClPeso molecular:351.31Clomipramine Hydrochloride
CAS:Fórmula:C19H23ClN2·HClPureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:351.32Clomipramine hydrochloride
CAS:Fórmula:C19H23ClN2·HClPureza:98.0 - 102.0 % (dried basis)Cor e Forma:White or almost white crystalline powderPeso molecular:351.32Clomipramine Hydrochloride
CAS:Produto Controlado<p>Applications Serotonin reuptake inhibitor. Antidepressant; antiobsessional agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Peters, M.D., et al.: Clin. Pharm., 9, 165 (1990), Adamczyk, M., et al.: Ther. Drug Monit., 17, 371 (1995), Poolsup, N., et al.: J. Clin. Pharm. Ther., 25, 197 (2000), Bose, D., et al.: J. Pharmacol. Toxicol. Methods, 52, 323 (2005),<br></p>Fórmula:C19H23ClN2·ClHCor e Forma:White To Off-WhitePeso molecular:351.31Clomipramine hydrochloride
CAS:Produto Controlado<p>Clomipramine hydrochloride is the hydrochloride salt form of clomipramine, an amphiphilic drug, derivative of dibenzazepine. It is presumed that this tricyclic compound affects serotonin uptake in the brain increasing thus the activity of serotonin. Also, clomipramine reduces the re-uptake of norepinephrine (active metabolite desmethylclomipramine) and binds to alpha-adrenergic, histaminergic, and cholinergic receptors (side effects). Clomipramine is antidepressant, used to treat obsessive compulsive disorder, panic disorders and cataplexy. Clomipramine is shown to modulate immune activation, shows constant anti-inflammatory properties at therapeutic concentrations by consistently decreasing pro- inflammatory cytokines. Clomipramine could be a good candidate to counteract SARS-CoV-2 infection worsening thanks to its high penetration in the brain and its anti-inflammatory effects.</p>Fórmula:C19H24Cl2N2Pureza:Min. 95%Cor e Forma:SolidPeso molecular:351.31 g/molClomipramine hydrochloride - Bio-X ™
CAS:Produto Controlado<p>Clomipramine is a tricyclic antidepressant drug that inhibits the reuptake of serotonin, norepinephrine, and dopamine. It is used to treat obsessive compulsive disorder, panic disorders and cataplexy. Additionally, Clomipramine is shown to modulate immune activation and shows constant anti-inflammatory properties at therapeutic concentrations by consistently decreasing pro-inflammatory cytokines.</p>Fórmula:C19H24Cl2N2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:351.31 g/mol
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