CAS 175481-36-4

Lacosamida

Descrição:

Lacosamida é um composto farmacêutico utilizado principalmente como anticonvulsivante no tratamento da epilepsia. É classificado como um aminoácido funcionalizado e é conhecido por sua capacidade de estabilizar as membranas neuronais e inibir a descarga neuronal repetitiva. A fórmula química de Lacosamida é C15H18N2O2, e apresenta uma estrutura única que inclui um anel fenila e um grupo funcional amida. Lacosamida atua melhorando a inativação dos canais de sódio dependentes de voltagem, o que ajuda a reduzir a excitabilidade dos neurônios. É tipicamente administrado por via oral ou intravenosa e é bem absorvido no trato gastrointestinal. A substância tem um perfil farmacocinético favorável, com uma meia-vida relativamente longa, permitindo a dosagem uma ou duas vezes ao dia. Efeitos colaterais comuns podem incluir tontura, náusea e dor de cabeça, mas geralmente é bem tolerado. Lacosamida também está sendo investigado para uso potencial em outros distúrbios neurológicos, refletindo seu amplo potencial terapêutico além da epilepsia.

Fórmula: C₁₃H₁₈N₂O₃

InChI: InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1

Chave InChI: InChIKey=VPPJLAIAVCUEMN-GFCCVEGCSA-N

SMILES: C(NC([C@H](NC(C)=O)COC)=O)C1=CC=CC=C1

Sinónimos:

• (2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide
• (2R)-2-Acetamido-N-benzyl-3-methoxypropanamide
• (2R)-2-acetamido-N-benzyl-3-methoxy-propanamide
• (R)-2-Acetamido-N-benzyl-3-methoxypropionamide
• (R)-2-acetamido-N-benzyl-3-methoxypropanamide
• Add 243037
• Erlosamide
• Harkoseride
• Lacosamide UCB
• Lacoset
• Lacoset 50
• N~2~-acetyl-N-benzyl-O-methyl-D-serinamide
• Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)-
• Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (R)-
• Spm 927

Lacosamide

CAS: 175481-36-4

Cor e Forma: Neat

Ref: 61-FOR3640.00

Lacosamide 1.0 mg/ml in Acetonitrile

Produto Controlado

CAS: 175481-36-4

Cor e Forma: Single Solution

Ref: 61-AMP3640.00-11

LACOSAMIDE FOR SYSTEM SUITABILITY CRS

CAS: 175481-36-4

LACOSAMIDE FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0001973

LACOSAMIDE CRS

CAS: 175481-36-4

LACOSAMIDE CRS

Ref: 41-Y0001982

Lacosamide

CAS: 175481-36-4

Fórmula: C₁₃H₁₈N₂O₃

Pureza: (HPLC) ≥ 98.0%

Cor e Forma: White to off-white powder

Peso molecular: 250.29

Ref: 7W-GP3690

Lacosamide

CAS: 175481-36-4

Fórmula: C₁₃H₁₈N₂O₃

Cor e Forma: White To Off-White Solid

Peso molecular: 250.30

Ref: 4Z-L-281

Lacosamide-d3 (Acetyl-d3)

CAS: 175481-36-4

Fórmula: C₁₃H₁₅D₃N₂O₃

Cor e Forma: White To Off-White Solid

Peso molecular: 253.32

Ref: 4Z-L-283

Lacosamide

Produto Controlado

CAS: 175481-36-4

Cor e Forma: Neat

Ref: 86-MM3640.00

Lacosamide

Produto Controlado

CAS: 175481-36-4

Applications Lacosamide is a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997), Barton, M., et al.: Epilepsy Res., 47, 217 (2001), Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006), Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007),

Fórmula: C₁₃H₁₈N₂O₃

Cor e Forma: Off-White

Peso molecular: 250.29

Ref: TR-L098500

Lacosamide - Bio-X ™

Produto Controlado

CAS: 175481-36-4

Lacosamide is a drug that is used for the treatment of epilepsy. It has been shown to inhibit neuronal death in vitro and in animal models, and has been extensively studied for its potential benefits in the treatment of bowel disease. The mechanism of action for lacosamide involves inhibition of the transport of neurotransmitters from the synaptic cleft by binding to the neuronal sodium channels and increasing their recovery rate. Lacosamide has also been found to affect energy metabolism by inhibiting the activity of mitochondrial enzymes such as matrix effect and complex I/III.

Fórmula: C₁₃H₁₈N₂O₃

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 250.29 g/mol

Ref: 3D-BL164605

Lacosamide

Produto Controlado

CAS: 175481-36-4

Lacosamide is a drug that is used for the treatment of epilepsy. It has been shown to inhibit neuronal death in vitro and in animal models, and has been extensively studied for its potential benefits in the treatment of bowel disease. The mechanism of action for lacosamide involves inhibition of the transport of neurotransmitters from the synaptic cleft by binding to the neuronal sodium channels and increasing their recovery rate. Lacosamide has also been found to affect energy metabolism by inhibiting the activity of mitochondrial enzymes such as matrix effect and complex I/III.

Fórmula: C₁₃H₁₈N₂O₃

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 250.29 g/mol

Ref: 3D-FL24825

Lacosamide-d6

Produto Controlado

CAS: 175481-36-4

Applications Labelled Lacosamide (L098500). Lacosamide is a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.
References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997), Barton, M., et al.: Epilepsy Res., 47, 217 (2001), Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006), Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007),

Fórmula: C₁₃D₆H₁₂N₂O₃

Cor e Forma: Neat

Peso molecular: 256.331

Ref: TR-L098503

Lacosamide CV ((+)-(R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide)

Produto Controlado

CAS: 175481-36-4

Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof

Fórmula: C₁₃H₁₈N₂O₃

Cor e Forma: White Light Yellow Powder

Peso molecular: 250.13174

Ref: 45-1357103