CAS 175735-93-0

α-Conotoxin MII

CAS: 175735-93-0

α-Conotoxin MII is a highly potent and selective competitive antagonist for α3β2 subunit-containing nicotinic receptors (IC50 = 0.5 - 3.5 nM at α3β2 expressed

Fórmula: C₆₇H₁₀₃N₂₃O₂₂S₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1710.94

Ref: TM-TP2063

α-Conotoxin MII

CAS: 175735-93-0

α-Conotoxin MII is a peptide toxin that binds to nicotinic acetylcholine receptors. α-Conotoxin MII can inhibit the activity of acetylcholine at the neuromuscular junction, leading to muscle paralysis. It has been shown to be a potent antagonist against nicotinic acetylcholine receptors in rat caudate putamen and human carcinoma cell lines. This peptide also inhibits nicotine-induced locomotor activity in rats and nicotine binding in rat liver cells. α-Conotoxin MII also blocks the ryanodine receptor, which is involved in calcium release from intracellular stores, leading to inhibition of cell proliferation and decreased cancer cell growth.

Fórmula: C₆₇H₁₀₃N₂₃O₂₂S₄

Pureza: Min. 95%

Peso molecular: 1,710.99 g/mol

Ref: 3D-AHA73593