CAS 17685-04-0

Etil β-D-glucuronídeo

Descrição:

Etil β-D-glucuronídeo (EtG) é um metabolito do etanol, formado através da conjugação do etanol com ácido glucurônico. É um composto incolor e solúvel em água que é frequentemente utilizado como um biomarcador para o consumo de álcool devido à sua presença na urina e em outros fluidos biológicos após a ingestão de etanol. EtG é caracterizado por sua estabilidade, que permite que seja detectado por um período mais longo em comparação com o próprio etanol, tornando-o uma ferramenta útil em testes de álcool. O composto é não volátil e tem um peso molecular relativamente baixo. Sua síntese envolve a ação enzimática de UDP-glucuronosiltransferases, que facilitam a transferência de ácido glucurônico para vários substratos, incluindo etanol. Etil β-D-glucuronídeo também é de interesse na farmacologia e toxicologia, pois pode fornecer insights sobre o metabolismo do álcool e seus efeitos no corpo. Devido à sua formação específica a partir do etanol, serve como um indicador confiável do consumo recente de álcool, auxiliando em investigações clínicas e forenses.

Fórmula: C₈H₁₄O₇

InChI: InChI=1S/C8H14O7/c1-2-14-8-5(11)3(9)4(10)6(15-8)7(12)13/h3-6,8-11H,2H2,1H3,(H,12,13)/t3-,4-,5+,6-,8+/m0/s1

Chave InChI: InChIKey=IWJBVMJWSPZNJH-UQGZVRACSA-N

SMILES: C(O)(=O)[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OCC)O1

Sinónimos:

• 6-Ethoxy-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylicAcid
• Ba 2829
• Ethyl -D-glucuronide
• Ethyl Glucuronide
• Ethyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• Ethyl β-<span class="text-smallcaps">D</span>-glucosiduronic acid
• Ethyl β-<span class="text-smallcaps">D</span>-glucuronide
• Glucopyranosiduronic acid, ethyl, β-<span class="text-smallcaps">D</span>-
• ethyl D-glucopyranosiduronic acid
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, ethyl
• Ethyl β-D-Glucuronide
• β-D-Glucopyranosiduronic acid, ethyl
• Ethyl β-D-glucopyranosiduronic acid
• Ethyl β-D-glucosiduronic acid

Ethyl-β-D-glucuronide, 1mg/ml in Methanol

CAS: 17685-04-0

Cor e Forma: Single Solution

Ref: LP-EGL-332-1LM

Ethyl-β-D-glucuronide

CAS: 17685-04-0

Cor e Forma: Neat

Ref: LP-EGL-332-10

β-D-Glucopyranosiduronic acid, ethyl

CAS: 17685-04-0

Fórmula: C₈H₁₄O₇

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 222.1926

Ref: IN-DA0024Z7

Ethyl b-D-glucuronide, 1mg/ml solution in Methanol

CAS: 17685-04-0

Fórmula: C₈H₁₄O₇

Peso molecular: 222.19

Ref: 7W-GW8904

Ethyl glucuronide

CAS: 17685-04-0

Ethyl glucuronide

Pureza: ≥98%

Peso molecular: 222.19g/mol

Ref: 54-BUP01629

Ethyl b-D-glucuronide

CAS: 17685-04-0

Fórmula: C₈H₁₄O₇

Pureza: ≥ 98.0%

Cor e Forma: White to off-white crystalline powder

Peso molecular: 222.19

Ref: 7W-GC5234

Ethyl glucuronide

CAS: 17685-04-0

Ethyl glucuronide (Ethyl-β-D-glucuronide) is a non-oxidized ethanol metabolite that is a biomarker of chronic alcohol consumption.

Fórmula: C₈H₁₄O₇

Pureza: 99.56%

Cor e Forma: Off-White Solid

Peso molecular: 222.19

Ref: TM-T11242

Ethyl D-Glucuronide

CAS: 17685-04-0

Fórmula: C₈H₁₄O₇

Peso molecular: 222.20

Ref: 4Z-A-862

Ethyl b-D-Glucuronide (1 mg/mL in Methanol)

Produto Controlado

CAS: 17685-04-0

Fórmula: C₈H₁₄O₇

Cor e Forma: Colourless

Peso molecular: 222.19

Ref: TR-KIT8320

Ethyl β-D-Glucuronide

CAS: 17685-04-0

Fórmula: C₈H₁₄O₇

Cor e Forma: White To Beige

Peso molecular: 222.19

Ref: TR-E918425

Ethyl β-D-glucuronide

CAS: 17685-04-0

Ethyl β-D-glucuronide (EBG) is a metabolite of ethanol that is formed by the conjugation of glucuronic acid to ethanol in the liver. EBG has been shown to be a potential biomarker for alcohol consumption, as it can be detected in urine and blood. The presence of this molecule has also been associated with an increased risk of developing type 2 diabetes mellitus, cardiovascular disease, and cancer. EBG may also have pharmacological effects as it has been shown to inhibit lipid oxidation and increase insulin sensitivity. This molecule can be extracted from human serum using solid phase microextraction

Fórmula: C₈H₁₄O₇

Pureza: Min. 98 Area-%

Cor e Forma: Slightly Brown Powder

Peso molecular: 222.19 g/mol

Ref: 3D-ME07200

Ethyl glucuronide

CAS: 17685-04-0

Pureza: 98%

Peso molecular: 222.07

Ref: 10-F557140

D3-Ethyl β-D-glucuronide

CAS: 17685-04-0

D3-Ethyl β-D-glucuronide is a metabolite of ethanol. Detection of this compound may be used to diagnose alcohol consumption during pregnancy. The detection time is approximately 5 hours after a single drink. D3-Ethyl β-D-glucuronide can be reliably detected in maternal blood using solid phase microextraction and LC-MS/MS methods. The body mass index (BMI) can be used to determine the risk for alcohol consumption during pregnancy, with higher BMIs indicating an increased risk. Logistic regression models were created to estimate the probability of D3-Ethyl β-D glucuronide being present in maternal blood and the probability of alcohol consumption during pregnancy given a positive result. These models were then used to create diagnostic tools that are sensitive enough for clinical use.

Fórmula: C₈H₁₁D₃O₇

Pureza: Min. 95%

Cor e Forma: White Off-White Powder

Peso molecular: 225.21 g/mol

Ref: 3D-ME29306