CAS 177325-13-2

Cloridrato de Levofloxacina

Descrição:

Cloridrato de Levofloxacina é um antibiótico sintético pertencente à classe das fluoroquinolonas, utilizado principalmente para tratar uma variedade de infecções bacterianas. É caracterizado por sua atividade de amplo espectro contra bactérias Gram-positivas e Gram-negativas, tornando-o eficaz para infecções do trato respiratório, infecções do trato urinário e infecções de pele. O composto é uma molécula quiral, com sua forma levorotatória sendo o isômero ativo, o que aumenta sua eficácia antibacteriana em comparação com sua contraparte racêmica. Cloridrato de Levofloxacina é tipicamente administrado por via oral ou intravenosa e é conhecido por sua boa biodisponibilidade. Seu mecanismo de ação envolve a inibição da girase do DNA bacteriano e da topoisomerase IV, enzimas cruciais para a replicação e transcrição do DNA. A substância é geralmente bem tolerada, embora possa causar efeitos colaterais como distúrbios gastrointestinais, efeitos no sistema nervoso central e, em casos raros, danos nos tendões. Devido ao seu potencial para desenvolver resistência, é importante usar levofloxacino de maneira judiciosa e de acordo com os padrões de suscetibilidade.

Fórmula: C₁₈H₂₀FN₃O₄·HCl

InChI: InChI=1/C18H20FN3O4.ClH/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21;/h7-8,10H,3-6,9H2,1-2H3,(H,24,25);1H/t10-;/m0./s1

Chave InChI: InChIKey=CAOOISJXWZMLBN-PPHPATTJSA-N

SMILES: O=C1C=2C3=C(C(=C(F)C2)N4CCN(C)CC4)OC[C@H](C)N3C=C1C(O)=O.Cl

Sinónimos:

• (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride
• (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride
• (S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride (1:1), (3S)-
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, monohydrochloride, (3S)-
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, monohydrochloride, (S)-
• Carboxylic Acid Monohydrochloride
• Levofloxacin Hcl
• LevofloxacinHydrochloride
• Weilisu
• Levofloxacin hydrochloride
• -7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride
• -9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)
• usp27 99% Levofloxacin white powder Antibacterial
• Levofloxacin white powder Antibacterial
• 3S)-9-Fluoro-2,3-dihydro-3-Methyl-10-(4-Methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid Monohydrochlori
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid, 9-fluoro-2,3-dihydro-3-Methyl-10-(4-Methyl-1-piperazinyl)-7-oxo-,hydrochloride (1:1), (3S)-

7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride (1:1), (3S)-

CAS: 177325-13-2

Fórmula: C₁₈H₂₁ClFN₃O₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 397.8284

Ref: IN-DA00258K

Levofloxacin hydrochloride

CAS: 177325-13-2

Fórmula: C₁₈H₂₀FN₃O₄·HCl

Pureza: ≥ 89.0% (C18H20FN3O4, dried basis)

Cor e Forma: Off-white to pale beige or light-yellow powder

Peso molecular: 397.9

Ref: 7W-GA2496

Levofloxacin Hydrochloride

CAS: 177325-13-2

Levofloxacin Hydrochloride

Pureza: 99%

Peso molecular: 397.83g/mol

Ref: 54-PC109232

Levofloxacin hydrochloride

CAS: 177325-13-2

Levofloxacin hydrochloride

Pureza: ≥98%

Peso molecular: 397.8g/mol

Ref: 54-BUP19621

Levofloxacin Hydrochloride

CAS: 177325-13-2

Fórmula: C₁₈H₂₀FN₃O₄·HCl

Pureza: >95.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 397.83

Ref: 3B-L0460

Levofloxacin hydrochloride

CAS: 177325-13-2

Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.

Fórmula: C₁₈H₂₁ClFN₃O₄

Pureza: 99.78% - 99.98%

Cor e Forma: Solid

Peso molecular: 397.8

Ref: TM-T8747

Levofloxacin hydrochloride

CAS: 177325-13-2

Levofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Levofloxacin has been shown to be effective against many infectious diseases, including urinary tract infections and some types of pneumonia. Levofloxacin also has inhibitory properties against gram-positive bacteria such as Streptococcus pyogenes and Staphylococcus aureus. The mechanism of action is not fully understood, but it is believed that levofloxacin interferes with protein synthesis by binding to the 30S subunit of the bacterial ribosome. The drug also binds to benzalkonium chloride (BAK) in wastewater treatment systems, which may contribute to its effectiveness in these

Fórmula: C₁₈H₂₀FN₃O₄•HCl

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 397.83 g/mol

Ref: 3D-FL104256

(S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride

CAS: 177325-13-2

Fórmula: C₁₈H₂₁ClFN₃O₄

Pureza: 98%

Cor e Forma: Solid, No data available.

Peso molecular: 397.83

Ref: 10-F054449

Levofloxacin Hydrochloride

CAS: 177325-13-2

Fórmula: C₁₈H₂₀FN₃O₄·(HCl)

Cor e Forma: White To Light Beige

Peso molecular: 361.37 + (36.46)

Ref: TR-L360258