CAS 177931-17-8

sauchinona

Descrição:

sauchinona é um composto químico que ocorre naturalmente e é classificado como um sesquiterpeno, derivado principalmente da espécie vegetal *Saururus cernuus*, comumente conhecida como cauda de lagarto. É caracterizado por sua complexa estrutura bicíclica, que contribui para suas propriedades químicas únicas. sauchinona exibe uma variedade de atividades biológicas, incluindo efeitos anti-inflamatórios, antioxidantes e potenciais efeitos anticancerígenos, tornando-se um assunto de interesse na pesquisa farmacológica. O composto é tipicamente encontrado na forma de um líquido incolor a amarelo pálido e tem um odor distinto. Sua solubilidade varia, sendo mais solúvel em solventes orgânicos do que em água. A fórmula molecular de sauchinona reflete sua composição de átomos de carbono, hidrogênio e oxigênio, que é típica dos sesquiterpenos. Devido às suas propriedades bioativas, sauchinona está sendo explorado para várias aplicações terapêuticas, embora mais estudos sejam necessários para entender completamente seus mecanismos de ação e possíveis usos na medicina.

Fórmula: C₂₀H₂₀O₆

InChI: InChI=1/C20H20O6/c1-9-3-11-13(21)5-17-20(25-8-24-17)19(11)18(10(9)2)12-4-15-16(23-7-22-15)6-14(12)26-20/h4-6,9-11,18-19H,3,7-8H2,1-2H3/t9-,10+,11+,18+,19+,20+/m1/s1

Chave InChI: InChIKey=GMTJIWUFFXGFHH-WPAOEJHSSA-N

SMILES: C[C@@H]1[C@@]2([C@]3([C@]4(C(=CC(=O)[C@@]3(C[C@H]1C)[H])OCO4)OC=5C2=CC6=C(C5)OCO6)[H])[H]

Sinónimos:

• (5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one
• (5aR,7R,8S,8aR,14aS,14bR)-7,8-dimethyl-5a,6,7,8,8a,14b-hexahydro-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one
• 5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-
• 5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aα,7α,8β,8aβ,14aS*,14bβ)-
• 5H-benzo[kl][1,3]dioxolo[4,5-b]-1,3-dioxolo[4,5-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-
• Sauchinone
• (5aα,7α,8β,8aβ,14aS*,14bβ)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one
• 5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-
• Sauchinone, 98%, from Saururus chinensis (Lour. ) Baill
• Sauchinone >=98% (HPLC)

Sauchinone

CAS: 177931-17-8

Fórmula: C₂₀H₂₀O₆

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 356.3692

Ref: IN-DA00AP2Q

Sauchinone

CAS: 177931-17-8

Sauchinone

Pureza: ≥98%

Peso molecular: 356.37g/mol

Ref: 54-BUP00983

Sauchinone

CAS: 177931-17-8

Sauchinone possesses diverse pharmacological properties, such as hepatoprotective, neuroprotective, anti-inflammatory and anti-tumor effects. Sauchinone protects skin keratinocytes through inhibition of extracellular signal-regulated kinase, c-Jun N-terminal kinase, and p38 MAPK signaling via upregulation of oxidative defense enzymes. Sauchinone can be used for the prevention of functional β-cell damage, it prevents cytokine-induced NO production, iNOS expression,JAK/STAT activation,and NF-κB activation and inhibition of glucose-stimulated insulin secretion (GSIS).

Fórmula: C₂₀H₂₀O₆

Pureza: 95%~99%

Peso molecular: 356.374

Ref: BP-BP1258

Sauchinone

CAS: 177931-17-8

Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.

Fórmula: C₂₀H₂₀O₆

Pureza: 99.12% - >99.99%

Cor e Forma: Solid

Peso molecular: 356.37

Ref: TM-T6S1572

Sauchinone

CAS: 177931-17-8

Fórmula: C₂₀H₂₀O₆

Peso molecular: 356.4

Ref: 7W-GL5788

Sauchinone

CAS: 177931-17-8

Oxygen-heterocyclic compound

Fórmula: C₂₀H₂₀O₆

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 356.37

Ref: 5G-83906

Sauchinone

CAS: 177931-17-8

Sauchinone is a natural compound that has shown to be effective in the treatment of bowel disease. This compound is an inhibitor of the toll-like receptor (TLR) and has shown to reduce inflammation and oxidative injury. Sauchinone has been found to increase the production of growth factor-β1, which may be useful for treating injuries such as burns or wounds. The matrix effect of sauchinone on cell culture was investigated using dextran sulfate, which is known to induce apoptosis in cells. Chromatographic analysis showed that sauchinone inhibited DNA binding activity and had an effect on dna binding activity. Molecular docking analysis showed that sauchinone binds with TLR4 and inhibits its signaling pathway, preventing aberrant reactions from occurring. Sauchinone also inhibits NF-κB activation by inhibiting nuclear translocation, thus suppressing inflammatory response.

Fórmula: C₂₀H₂₀O₆

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 356.37 g/mol

Ref: 3D-FS73944