CAS 1781834-71-6

Cgp 36216 hydrochloride

CAS: 1781834-71-6

CGP 36216 hydrochloride is a GABA receptor agonist that has been shown to have both mediated and spontaneous activity. It has a high affinity for the gamma-aminobutyric acid (GABA) receptor and its effects on the GABA receptor are antagonistic. CGP 36216 hydrochloride is used in the treatment of seizures and can be used as an adjunct to baclofen preparations in the treatment of spasticity. CGP 36216 hydrochloride has been shown to increase frequency of spontaneous inhibitory postsynaptic currents in neocortical neurons, which may be due to its ability to activate presynaptic GABA receptors.

Fórmula: C₅H₁₅ClNO₂P

Pureza: Min. 95%

Peso molecular: 187.6 g/mol

Ref: 3D-GWC83471

CGP36216 hydrochloride

CAS: 1781834-71-6

CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].

Fórmula: C₅H₁₅ClNO₂P

Cor e Forma: Solid

Peso molecular: 187.6

Ref: TM-T84878