CAS 1784-03-8

L-Arginina, N2-[(4-metilfenil)sulfonil]-, éster metílico, cloridrato (1:1)

Descrição:

L-Arginina, N2-[(4-metilfenil)sulfonil]-, éster metílico, cloridrato (1:1) é um composto químico que apresenta uma combinação de um aminoácido, L-arginina, e um grupo sulfonila ligado a um moiety de metilfenila. Este composto é caracterizado por sua estrutura de aminoácido básico, que inclui um grupo guanidínio, contribuindo para seu papel em vários processos biológicos, como a síntese de proteínas e a produção de óxido nítrico. A presença do éster metílico indica que é um derivado da L-arginina, que pode melhorar sua solubilidade e biodisponibilidade. A forma de cloridrato sugere que é um sal, que tipicamente melhora a estabilidade e as propriedades de manuseio. Este composto pode exibir várias atividades farmacológicas, incluindo papéis potenciais na saúde cardiovascular e na função imunológica. Seu grupo sulfonila também pode influenciar sua reatividade e interação com alvos biológicos. No geral, L-Arginina, N2-[(4-metilfenil)sulfonila]-, éster metílico, cloridrato é de interesse tanto na pesquisa bioquímica quanto em aplicações terapêuticas potenciais.

Fórmula: C₁₄H₂₂N₄O₄S·ClH

InChI: InChI=1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1

Chave InChI: InChIKey=JIQFFACVQXXHMY-YDALLXLXSA-N

SMILES: S(N[C@@H](CCCNC(=N)N)C(OC)=O)(=O)(=O)C1=CC=C(C)C=C1.Cl

Sinónimos:

• <span class="text-smallcaps">L</span>-Arginine, N²-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)
• <span class="text-smallcaps">L</span>-Arginine, N²-[(4-methylphenyl)sulfonyl]-, methyl ester, monohydrochloride
• Arginine, N²-(p-tolylsulfonyl)-, methyl ester, monohydrochloride, <span class="text-smallcaps">L</span>-
• N-alpha-Toluenesulfonylarginine methyl ester hydrochloride
• N-alpha-Tosyl-L-arginine methyl ester hydrochloride
• N-p-Tosyl-L-arginine methyl ester hydrochloride
• N-α-p-Tosyl-L-arginine methyl ester hydrochloride
• N^α-Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• Nalpha-(4-Toluenesulfonyl)-L-Arginine Methyl Ester Hydrochloride
• Tame
• Tos-Arg-OMe . HCl
• Tos-Arg-OMe・HCl
• Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• Tosylarginine methyl ester hydrochloride
• methyl N5-(diaminomethylidene)-N2-[(4-methylphenyl)sulfonyl]-L-ornithinate hydrochloride
• methyl N5-(diaminomethylidene)-N2-[(4-methylphenyl)sulfonyl]ornithinate hydrochloride
• na-P-tosyl-L-arginine methyl*ester hydrochloride
• α-N-Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)
• α-N-Tosyl-L-arginine methyl ester hydrochloride
• Nα-Tosyl-L-arginine methyl ester hydrochloride
• L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, monohydrochloride

Nα-Tosyl-L-arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

Fórmula: C₁₄H₂₂N₄O₄S·HCl

Pureza: >98.0%(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 378.87

Ref: 3B-T0330

Tos-Arg-OMe · HCl

CAS: 1784-03-8

A good substrate for trypsin, thrombin, and urokinase as well as for plasma and glandular kallikreins. By competing for the arginine-binding site in the reactive center of proteases, L-TAME is also able to act as a reversible inhibitor. It suppresses, e.g., the TNF secretion of human leukocytes which is evidently dependent upon the action of serine proteases.

Fórmula: C₁₄H₂₂N₄O₄S·HCl

Pureza: > 99%

Cor e Forma: White Powder

Peso molecular: 378.88

Ref: 01-4002251

L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)

CAS: 1784-03-8

Fórmula: C₁₄H₂₃ClN₄O₄S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 378.8748

Ref: IN-DA0025ZQ

TAME hydrochloride

CAS: 1784-03-8

TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.

Fórmula: C₁₄H₂₃ClN₄O₄S

Pureza: 99.11% - 99.21%

Cor e Forma: White Fine Crystalline Powder

Peso molecular: 378.87

Ref: TM-T1731

TAME hydrochloride

CAS: 1784-03-8

TAME hydrochloride

Pureza: ≥95%

Peso molecular: 378.87g/mol

Ref: 54-BUP17017

N-α-p-Tosyl-L-Arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

N-α-p-Tosyl-L-Arginine Methyl Ester Hydrochloride

Pureza: 98%

Peso molecular: 378.87g/mol

Ref: 54-OR1014507

TAME Hydrochloride

CAS: 1784-03-8

Fórmula: C₁₄H₂₂N₄O₄S·HCl

Pureza: ≥ 98.0%

Cor e Forma: White to almost white powder

Peso molecular: 378.87

Ref: 7W-GM4942

N-α-Tosyl-L-arginine methyl ester hydrochloride

CAS: 1784-03-8

N-alpha-Tosyl-L-arginine methyl ester hydrochloride is a potent inhibitor of the serine protease leishmania. It inhibits the enzyme by binding to its active site and interfering with the enzymatic reaction. This drug has been shown to be effective in treating bladder infections caused by leishmania, although it can cause a decrease in responsiveness in an animal model. N-alpha-Tosyl-L-arginine methyl ester hydrochloride also has anti-HIV activities, which may be due to its ability to inhibit HIV replication. The drug is most likely absorbed through the apical surface of the bladder epithelium and then diffuses into the extracellular space, where it inhibits key enzymes involved in viral replication.

Fórmula: C₁₄H₂₂N₄O₄S·HCl

Pureza: Min. 95%

Cor e Forma: White Off-White Powder

Peso molecular: 378.88 g/mol

Ref: 3D-FT55915

TAME hydrochloride

CAS: 1784-03-8

Pureza: 98%

Peso molecular: 378.87

Ref: 10-M03112

N-4-Tosyl-L-arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

Applications N-4-Tosyl-L-arginine Methyl Ester Hydrochloride acts as a synthetic substrate of serine proteases and thus is used to determine serine proteases from diverse organic sources.
References Hummel, B. et al.: Can. J. Biochem. Physiol., 37, 1393 (1959); Matsuda, Y. et al.: J. Biochem. 80, 671 (1976);

Fórmula: C₁₄H₂₃ClN₄O₄S

Cor e Forma: Neat

Peso molecular: 378.87

Ref: TR-T570000

TAME hydrochloride

CAS: 1784-03-8

Tos-Arg-OMe • HCl is a peptide that has been shown to modulate the responsiveness of cells to sodium channels. Tos-Arg-OMe • HCl may also be useful as an anti-cancer drug, as it inhibits cancer cell growth and induces apoptosis. This peptide has been shown to be an effective treatment for HIV infection by inhibiting viral replication. It also reduces inflammation and prevents the development of other opportunistic infections in animal models.

Fórmula: C₁₄H₂₂N₄O₄S·ClH

Pureza: Min. 95%

Peso molecular: 378.87 g/mol

Ref: 3D-STR-3003